Analysis of VH genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity

Autor: AB Rickinson, M Rowe, Freda K. Stevenson, Caroline J. Chapman, C I Mockridge

Publikováno v: Blood. 85:2176-2181

Tumor cell lines from six typical cases of endemic Epstein-Barr virus (EBV) genome-positive Burkitt's lymphoma (BL) have been investigated for usage and mutational pattern of Ig VH genes. The neoplastic cells all had a t(8;14) (q24;q32) translocation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::66cd85e2ad14d94c242594cdac665b27
https://doi.org/10.1182/blood.v85.8.2176.bloodjournal8582176

Protective T-cell responses against tumours

Autor: Rolf Kiessling, R. Dunbar, AB Rickinson, P. Ricciardi-Castagnoli, G. Forni, Cornelis J. M. Melief, N. Annels, B Van den Eynde

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac71c4478f44c7e3dbef9034ae2f60a
https://doi.org/10.1016/s0923-2494(99)80019-4

Analysis of Epstein-Barr virus gene polymorphisms in normal donors and in virus-associated tumors from different geographic locations

Autor: Khanim F, Qy, Yao, Gerald Niedobitek, Sihota S, Ab, Rickinson, Ls, Young

Publikováno v: Europe PubMed Central

While Epstein-Barr virus (EBV) infection is associated with the development of certain lymphoid and epithelial tumors, the role of the virus in the pathogenesis of these malignancies remains unknown. It has been suggested that EBV strain variation ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f83c20d26a39250e79d69459c499ea42
https://pubmed.ncbi.nlm.nih.gov/8896415

T cell recognition of Epstein-Barr virus associated lymphomas

Autor: Ab, Rickinson, Rj, Murray, Brooks J, Griffin H, Dj, Moss, Maria Masucci

Publikováno v: Europe PubMed Central

Epstein-Barr virus, a lymphotropic herpesvirus of humans, has potent B cell growth transforming activity yet persists in the lymphoid tissues of most individuals as a lifelong asymptomatic infection. Virus induced B cell growth transformation in vitr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::46c59490566a74ae60fe1271fca2c7e2
https://pubmed.ncbi.nlm.nih.gov/1330300

EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins.

Autor: Fitzsimmons L; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. l.fitzsimmons@bham.ac.uk., Cartlidge R; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Chang C; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia., Sejic N; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, VIC, 3052, Australia.; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Galbraith LCA; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK., Suraweera CD; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Croom-Carter D; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Dewson G; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, VIC, 3052, Australia., Tierney RJ; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Bell AI; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Shannon-Lowe C; Institute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Herold MJ; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, VIC, 3052, Australia., Rickinson AB; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Colman PM; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, VIC, 3052, Australia., Huang DCS; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, VIC, 3052, Australia., Strasser A; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, VIC, 3052, Australia., Kvansakul M; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Rowe M; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Kelly GL; The Walter and Eliza Hall Institute for Medical Research, Parkville, Melbourne, VIC, 3052, Australia. gkelly@wehi.edu.au.; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, VIC, 3052, Australia. gkelly@wehi.edu.au.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2020 May; Vol. 27 (5), pp. 1554-1568. Date of Electronic Publication: 2019 Oct 23.