Long-term clinical and radiological effectiveness and safety of ultralow doses of rituximab in rheumatoid arthritis: observational extension of the REDO trial

Autor: Nathan den Broeder, Aatke van der Maas, Alfons A den Broeder, Bart JF van den Bemt, Frank HJ van den Hoogen, Yael A de Man, Marc R Kok, Lise Verhoef, Rogier Thurlings, Wilfred van der Weele

Publikováno v: RMD Open, Vol 10, Iss 2 (2024)

Background The REDO trial (REtreatment with Rituximab in RhEmatoid arthritis: Disease Outcome after Dose Optimisation) showed similar disease activity for retreatment with ultralow doses (200 mg and 500 mg per 6 months) compared with standard low-dos

Externí odkaz: https://doaj.org/article/12646c2bca3040469a48a59a6f5fa167

(Dis)agreement of polymyalgia rheumatica relapse criteria, and prediction of relapse in a retrospective cohort

Autor: Thomas E. Bolhuis, Diane Marsman, Frank H. J. van den Hoogen, Alfons A. den Broeder, Nathan den Broeder, Aatke van der Maas

Publikováno v: BMC Rheumatology, Vol 6, Iss 1, Pp 1-8 (2022)

Abstract Background To develop and assess a prediction model for polymyalgia rheumatica (PMR) relapse within the first year of glucocorticoid (GC) treatment. Methods A retrospective PMR cohort (clinical diagnosis) from a rheumatology department was u

Externí odkaz: https://doaj.org/article/d175a1689d354123a4d926104e990ace

Dose reduction and withdrawal strategy for TNF-inhibitors in psoriatic arthritis and axial spondyloarthritis: design of a pragmatic open-label, randomised, non-inferiority trial

Autor: Celia A. J. Michielsens, Nadine Boers, Nathan den Broeder, Mark H. Wenink, Aatke van der Maas, Elien A. M. Mahler, Michelle L. M. Mulder, Désirée van der Heijde, Frank H. J. van den Hoogen, Lise M. Verhoef, Alfons A. den Broeder

Publikováno v: Trials, Vol 21, Iss 1, Pp 1-12 (2020)

Abstract Background Tumour necrosis factor inhibitors (TNFi) are effective in the treatment of patients with spondyloarthritis (SpA), including psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA). However, these drugs come with some disadva

Externí odkaz: https://doaj.org/article/57219f3f31494167bd5e7678b9c9b2fc

An international survey of current management practices for polymyalgia rheumatica by general practitioners and rheumatologists

Autor: Agnete Overgaard Donskov, Sarah Louise Mackie, Ellen Margrethe Hauge, Carlos Enrique Toro-Gutiérrez, Ib Tønder Hansen, Andrea Katharina Hemmig, Aatke Van der Maas, Tamer Gheita, Berit Dalsgaard Nielsen, Karen M J Douglas, Richard Conway, Elena Rezus, Bhaskar Dasgupta, Sara Monti, Eric L Matteson, Sebastian E Sattui, Mark Matza, Vanessa Ocampo, Margarita Gromova, Rebecca Grainger, Andrea Bran, Simone Appenzeller, Annelise Goecke, Nelly Colman, Helen I Keen, Masataka Kuwana, Latika Gupta, Babur Salim, Ghita Harifi, Mariam Erraoui, Nelly Ziade, Nizar Abdulateef Al-Ani, Adeola Ajibade, Johannes Knitza, Line Frølund, Max Yates, Victor R Pimentel-Quiroz, Andre Marun Lyrio, Maria Sandovici, Kornelis S M Van der Geest, Toby Helliwell, Elisabeth Brouwer, Christian Dejaco, Kresten Krarup Keller

Publikováno v: Donskov, A O, Mackie, S L, Hauge, E M, Toro-Gutiérrez, C E, Hansen, I T, Hemmig, A K, Van der Maas, A, Gheita, T, Nielsen, B D, Douglas, K M J, Conway, R, Rezus, E, Dasgupta, B, Monti, S, Matteson, E L, Sattui, S E, Matza, M, Ocampo, V, Gromova, M, Grainger, R, Bran, A, Appenzeller, S, Goecke, A, Colman, N, Keen, H I, Kuwana, M, Gupta, L, Salim, B, Harifi, G, Erraoui, M, Ziade, N, Al-Ani, N A, Ajibade, A, Knitza, J, Frølund, L, Yates, M, Pimentel-Quiroz, V R, Lyrio, A M, Sandovici, M, Van der Geest, K S M, Helliwell, T, Brouwer, E, Dejaco, C & Keller, K K 2023, ' An international survey of current management practices for polymyalgia rheumatica by general practitioners and rheumatologists ', Rheumatology (Oxford, England) . https://doi.org/10.1093/rheumatology/keac713

Objectives To explore current management practices for PMR by general practitioners (GPs) and rheumatologists including implications for clinical trial recruitment. Methods An English language questionnaire was constructed by a working group of rheum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1aaacc6c78d2aa516cc19eca6cb0121
https://pure.au.dk/portal/da/publications/an-international-survey-of-current-management-practices-for-polymyalgia-rheumatica-by-general-practitioners-and-rheumatologists(f5eef5d5-f759-4c40-b686-82012dbfac1f).html

Efficacy of rituximab in patients with polymyalgia rheumatica: a double-blind, randomised, placebo-controlled, proof-of-concept trial

Autor: Nathan den Broeder, Alfons A den Broeder, Aatke van der Maas, Frank H. J. van den Hoogen, D. Marsman

Publikováno v: The Lancet. Rheumatology, 3, e758-e766
The Lancet. Rheumatology, 3, 11, pp. e758-e766

Summary Background Glucocorticoids remain the cornerstone of polymyalgia rheumatica treatment, but their use has several drawbacks, such as long treatment duration and glucocorticoid-related adverse events. Effective glucocorticoid-sparing agents wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04671f797230842fa7aa5e44c21f1651
https://doi.org/10.1016/s2665-9913(21)00245-9