Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aashutosh Vihani"'
Autor:
Aashutosh Vihani, Xiaoyang Serene Hu, Sivaji Gundala, Sachiko Koyama, Eric Block, Hiroaki Matsunami
Publikováno v:
eLife, Vol 9 (2020)
Understanding how genes and experience work in concert to generate phenotypic variability will provide a better understanding of individuality. Here, we considered this in the main olfactory epithelium, a chemosensory structure with over a thousand d
Externí odkaz:
https://doaj.org/article/72239086c38d47c4ae9ceb71183df50a
Autor:
Hitoshi Kida, Yosuke Fukutani, Joel D. Mainland, Claire A. de March, Aashutosh Vihani, Yun Rose Li, Qiuyi Chi, Akemi Toyama, Linda Liu, Masaharu Kameda, Masafumi Yohda, Hiroaki Matsunami
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Biomimetic “noses” have been proposed to replace trained animals for chemical detection. Here the authors select 31 mouse olfactory receptors (ORs), based on a large cell-based screen of >800 ORs against seven chemicals, to build an OR-based sens
Externí odkaz:
https://doaj.org/article/4bb70edca5cc4c01907d20a917e26727
Autor:
Aashutosh Vihani, Maira H. Nagai, Conan Juan, Claire A. de March, Xiaoyang S. Hu, John Pearson, Hiroaki Matsunami
Identified ligands for > 500 mouse ORsORs are specifically tuned towards individual odorants and their molecular propertiesOdor molecular properties are informative of odor responsesPredictive modeling and convergent evolution analyses suggest specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::974b33a51b30c42d0d975c56ac5b150f
https://doi.org/10.1101/2021.12.27.474279
https://doi.org/10.1101/2021.12.27.474279
Autor:
Hiroaki Matsunami, Aashutosh Vihani, Sachiko Koyama, Xiaoyang Serene Hu, Eric Block, Sivaji Gundala
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Understanding how genes and experiences work in concert to generate phenotypic variability will provide a better understanding of individuality. Here, we considered this in the context of the main olfactory epithelium, a chemosensory structure with o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808207092a596f31b9f6e60c7639d532
https://doi.org/10.7554/elife.54501
https://doi.org/10.7554/elife.54501
Publikováno v:
J Vis Exp
Olfactory perception begins with the interaction of odorants with odorant receptors (OR) expressed by olfactory sensory neurons (OSN). Odor recognition follows a combinatorial coding scheme, where one OR can be activated by a set of odorants and one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f6cfe2431f2ff380053928d2aeacf3
https://europepmc.org/articles/PMC7263640/
https://europepmc.org/articles/PMC7263640/
Autor:
Hiroaki Matsunami, Aashutosh Vihani, Natasha Vaidya, Xiaoyang Serene Hu, Marcelo Zapata, Kentaro Ikegami, Gary Kucera, Masafumi Yohda, Cheryl B. Bock, Kevin W. Zhu, Claire A. de March, Yue Jiang, Matthew Do
Publikováno v:
eNeuro
A fundamental challenge in studying principles of organization used by the olfactory system to encode odor concentration information has been identifying comprehensive sets of activated odorant receptors (ORs) across a broad concentration range insid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13023c01f57e401cd0b8b44cea1b18f6
https://doi.org/10.1523/eneuro.0103-19.2019
https://doi.org/10.1523/eneuro.0103-19.2019
Autor:
Joel D. Mainland, Akemi Toyama, Linda Liu, Aashutosh Vihani, Hitoshi Kida, Hiroaki Matsunami, Yosuke Fukutani, Masafumi Yohda, Claire A. de March, Masaharu Kameda, Qiuyi Chi, Yun Li
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Olfactory systems have evolved the extraordinary capability to detect and discriminate volatile odorous molecules (odorants) in the environment. Fundamentally, this process relies on the interaction of odorants and their cognate olfactory receptors (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f39935e971e97c6a9b117701e7db97e
https://pubmed.ncbi.nlm.nih.gov/30385742
https://pubmed.ncbi.nlm.nih.gov/30385742
Publikováno v:
Biophysical Journal. (2):430a
We are examining the M3 transmembrane helix of mouse muscle AChRs with regard to C↔O gating and the effects of positive allosteric modulators (PAMs). The relative ground and transition state gating energies were estimated from single-channel curren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c5cdc48d23ee751596bae94f5532f8