Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Aashreya Ravichandra"'
Publikováno v:
Advances in cancer research. 156
Cancer-associated fibroblasts (CAFs) are one of the most abundant stromal cell type in the tumor microenvironment (TME) of intrahepatic cholangiocarcinoma (iCCA), where they are actively involved in cancer progression through a complex network of int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3260a16b353a04ab39562bee08ce6862
https://pubmed.ncbi.nlm.nih.gov/35961700
https://pubmed.ncbi.nlm.nih.gov/35961700
Autor:
Ingmar Mederacke, Aveline Filliol, Silvia Affo, Ajay Nair, Celine Hernandez, Qiuyan Sun, Florian Hamberger, Francesco Brundu, Yu Chen, Aashreya Ravichandra, Peter Huebener, Helena Anke, Hongxue Shi, Raquel A. Martínez García de la Torre, James R. Smith, Neil C. Henderson, Florian W. R. Vondran, Carla V. Rothlin, Heike Baehre, Ira Tabas, Pau Sancho-Bru, Robert F. Schwabe
Publikováno v:
Sci Transl Med
Fibrosis contributes to ~45% of deaths in western countries. In chronic liver disease, fibrosis is a major factor determining outcomes, but efficient antifibrotic therapies are lacking. Although platelet-derived growth factor and transforming growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bc14a6084b1e42865dd1b435d1e12c
https://doi.org/10.1126/scitranslmed.abe5795
https://doi.org/10.1126/scitranslmed.abe5795
Publikováno v:
Advances in Cancer Research ISBN: 9780323983921
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::121e5907cb0e2713fe7b250cdc37ea86
https://doi.org/10.1016/bs.acr.2022.01.009
https://doi.org/10.1016/bs.acr.2022.01.009
Publikováno v:
Nature
Cellular senescence is characterized by stable cell cycle arrest and a secretory program that modulates the tissue microenvironment1,2. Physiologically, senescence serves as a tumor suppressive mechanism that prevents the expansion of premalignant ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e452facb2dec6dfe8968f8b5a9c1ba7
https://doi.org/10.1002/hep.31596
https://doi.org/10.1002/hep.31596
Autor:
Nicholas Arpaia, Florian Hamberger, Raghu Kalluri, Ekihiro Seki, Thomas Savage, Di Zhu, Likang Chin, Ingmar Mederacke, Ajay Nair, Rebecca G. Wells, Maximilian Miller, Naita Maren Wirsik, Silvia Affò, Robert F. Schwabe, Aveline Filliol, Thomas Schmidt, Ben Z. Stanger, Matthias Mack, Kenneth P. Olive, Aashreya Ravichandra, Sonakshi Bhattacharjee, Peter A. Sims, Adam Mehal, Deqi Yin
Publikováno v:
J Clin Invest
The Journal of clinical investigation, vol 131, iss 11
The Journal of clinical investigation, vol 131, iss 11
Cancer-associated fibroblasts (CAF) may exert tumor-promoting and tumor-suppressive functions, but the mechanisms underlying these opposing effects remain elusive. Here, we sought to understand these potentially opposing functions by interrogating fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac8ee79b76e4d7e3c884e98a4fc194e
https://doi.org/10.1172/jci146987
https://doi.org/10.1172/jci146987
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2299
Liver fibrosis is defined as excessive accumulation of extracellular matrix, and results from maladaptive wound healing processes that occur in response to chronic liver injury and inflammation. The main etiologies of liver fibrosis include nonalcoho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29d9ceacec0f78a96618f080db7ea41d
https://pubmed.ncbi.nlm.nih.gov/34028753
https://pubmed.ncbi.nlm.nih.gov/34028753
Autor:
Aveline Filliol, Yoshinobu Saito, Ajay Nair, Dianne H. Dapito, Le-Xing Yu, Aashreya Ravichandra, Sonakshi Bhattacharjee, Silvia Affo, Naoto Fujiwara, Hua Su, Qiuyan Sun, Thomas M. Savage, John R. Wilson-Kanamori, Jorge M. Caviglia, LiKang Chin, Dongning Chen, Xiaobo Wang, Stefano Caruso, Jin Ku Kang, Amit Dipak Amin, Sebastian Wallace, Ross Dobie, Deqi Yin, Oscar M. Rodriguez-Fiallos, Chuan Yin, Adam Mehal, Benjamin Izar, Richard A. Friedman, Rebecca G. Wells, Utpal B. Pajvani, Yujin Hoshida, Helen E. Remotti, Nicholas Arpaia, Jessica Zucman-Rossi, Michael Karin, Neil C. Henderson, Ira Tabas, Robert F. Schwabe
Publikováno v:
Nature
Hepatocellular carcinoma (HCC), the fourth leading cause of cancer mortality, develops almost exclusively in patients with chronic liver disease (CLD) and advanced fibrosis(1,2). Here we interrogated functions of hepatic stellate cells (HSC), the mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0621acacd23dedf5008c509db3412562
https://pubmed.ncbi.nlm.nih.gov/36198802
https://pubmed.ncbi.nlm.nih.gov/36198802
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613818
Liver fibrosis is defined as excessive accumulation of extracellular matrix, and results from maladaptive wound healing processes that occur in response to chronic liver injury and inflammation. The main etiologies of liver fibrosis include nonalcoho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44e6192c4c61b1c2b5eb61a660c7076
https://doi.org/10.1007/978-1-0716-1382-5_23
https://doi.org/10.1007/978-1-0716-1382-5_23
Autor:
Silvia Affò, Aashreya Ravichandra, Francesco Brundu, Aveline Filliol, LiKang Chin, Wen Wen, Deqi Yin, Sonakshi Bhattacharjee, Raul Rabadan, Raghu Kalluri, Lars Zender, Rebecca Wells, Xin Chen, Robert F. Schwabe
Publikováno v:
Journal of Hepatology. 73:S17-S18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79d017f53f59f40095c28e51e9ccf9a3
https://doi.org/10.1016/s0168-8278(20)30594-8
https://doi.org/10.1016/s0168-8278(20)30594-8