Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Aartjan J W te Velthuis"'
Autor:
Jurre Y Siegers, Lucas Ferreri, Dirk Eggink, Edwin J B Veldhuis Kroeze, Aartjan J W Te Velthuis, Marco van de Bildt, Lonneke Leijten, Peter van Run, Dennis de Meulder, Theo Bestebroer, Mathilde Richard, Thijs Kuiken, Anice C Lowen, Sander Herfst, Debby van Riel
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011214 (2023)
Central nervous system (CNS) disease is the most common extra-respiratory tract complication of influenza A virus infections in humans. Remarkably, zoonotic highly pathogenic avian influenza (HPAI) H5N1 virus infections are more often associated with
Externí odkaz:
https://doaj.org/article/6b06d78f37544d44bd9dcafbc3513635
Autor:
Adeyemi O Adedeji, Bruno Marchand, Aartjan J W Te Velthuis, Eric J Snijder, Susan Weiss, Robert L Eoff, Kamalendra Singh, Stefan G Sarafianos
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36521 (2012)
The non-structural protein 13 (nsp13) of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is a helicase that separates double-stranded RNA (dsRNA) or DNA (dsDNA) with a 5' → 3' polarity, using the energy of nucleotide hydrolysis. We determi
Externí odkaz:
https://doaj.org/article/76581fc99ad048059d5b00d92b33f4f4
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16047 (2011)
Binding selectivity and cross-reactivity within one of the largest and most abundant interaction domain families, the PDZ family, has long been enigmatic. The complete human PDZ domain complement (the PDZome) consists of 267 domains and we applied he
Externí odkaz:
https://doaj.org/article/94cb0839d44940aa8dfeeb6c97fca5d0
Autor:
Aartjan J W te Velthuis, Sjoerd H E van den Worm, Amy C Sims, Ralph S Baric, Eric J Snijder, Martijn J van Hemert
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001176 (2010)
Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed
Externí odkaz:
https://doaj.org/article/7cdd7f65b52d469c877fb5e4218274e6
Publikováno v:
PLoS ONE, Vol 2, Iss 2, p e189 (2007)
The PDZ and LIM domain-containing protein family is encoded by a diverse group of genes whose phylogeny has currently not been analyzed. In mammals, ten genes are found that encode both a PDZ- and one or several LIM-domains. These genes are: ALP, RIL
Externí odkaz:
https://doaj.org/article/2871be505d484d45bbeb77849050b5b0
Publikováno v:
bioRxiv
The influenza A (IAV) RNA polymerase is an essential driver of IAV evolution. Mutations that the polymerase introduces into viral genome segments during replication are the ultimate source of genetic variation, including within the three subunits of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9f2393afe127ddcad9375faeb5c20d
https://doi.org/10.1101/2023.02.16.528850
https://doi.org/10.1101/2023.02.16.528850
Publikováno v:
mBio. 13
RNA viruses include respiratory viruses, such as coronaviruses and influenza viruses, as well as vector-borne viruses, like dengue and West Nile virus. RNA viruses like these encounter various environments when they copy themselves and spread from ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52465f4488b8ee1a0f1fb33e871dca06
https://doi.org/10.1128/mbio.02021-22
https://doi.org/10.1128/mbio.02021-22
Publikováno v:
Journal of Virology. 96
Influenza A viruses are negative-sense RNA viruses that rely on their own viral replication machinery to replicate and transcribe their segmented single-stranded RNA genome. The viral ribonucleoprotein complexes in which viral RNA is replicated consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8360c61cad82b3bee9526c7ea50985e5
https://doi.org/10.1128/jvi.02092-21
https://doi.org/10.1128/jvi.02092-21
Publikováno v:
Cellular and Molecular Life Sciences
Influenza A viruses cause a mild-to-severe respiratory disease that affects millions of people each year. One of the many determinants of disease outcome is the innate immune response to the viral infection. While antiviral responses are essential fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae027898660f8b4a618b621bb7ee9d2c
https://www.repository.cam.ac.uk/handle/1810/331467
https://www.repository.cam.ac.uk/handle/1810/331467
Autor:
William K. Reiser, Christopher B. Brooke, Aartjan J. W. te Velthuis, Fadi G. Alnaji, Joel Rivera-Cardona
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
mBio
mBio
Deletion-containing viral genomes (DelVGs) are commonly produced during influenza A virus infection and have been implicated in influencing clinical infection outcomes. Despite their ubiquity, the specific molecular mechanisms that govern DelVG forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d00f482fd08dba0d34fa171d55ec085
https://journals.asm.org/doi/10.1128/mBio.02959-21
https://journals.asm.org/doi/10.1128/mBio.02959-21