Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Aartik, Sarma"'
Autor:
Lucile P. A. Neyton, Ravi K. Patel, Aartik Sarma, UCSF COMET Consortium, Andrew Willmore, Sidney C. Haller, Kirsten N. Kangelaris, Walter L. Eckalbar, David J. Erle, Matthew F. Krummel, Carolyn M. Hendrickson, Prescott G. Woodruff, Charles R. Langelier, Carolyn S. Calfee, Gabriela K. Fragiadakis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its immunological effects in this setting are not understood. Here we perform bulk and single-cell RNA se
Externí odkaz:
https://doaj.org/article/a07e6d9546564fe3af6acbe7a47ce91d
Autor:
Jason A. Hackney, Haridha Shivram, Jason Vander Heiden, Chris Overall, Luz Orozco, Xia Gao, Eugene Kim, Nathan West, Aditi Qamra, Diana Chang, Arindam Chakrabarti, David F. Choy, Alexis J. Combes, Tristan Courau, Gabriela K. Fragiadakis, Arjun Arkal Rao, Arja Ray, Jessica Tsui, Kenneth Hu, Nicholas F. Kuhn, Matthew F. Krummel, David J. Erle, Kirsten Kangelaris, Aartik Sarma, Zoe Lyon, Carolyn S. Calfee, Prescott G. Woodruff, Rajani Ghale, Eran Mick, Ashley Byrne, Beth Shoshana Zha, Charles Langelier, Carolyn M. Hendrickson, Monique G.P. van der Wijst, George C. Hartoularos, Tianna Grant, Raymund Bueno, David S. Lee, John R. Greenland, Yang Sun, Richard Perez, Anton Ogorodnikov, Alyssa Ward, Chun Jimmie Ye, Thiru Ramalingam, Jacqueline M. McBride, Fang Cai, Anastasia Teterina, Min Bao, Larry Tsai, Ivan O. Rosas, Aviv Regev, Sharookh B. Kapadia, Rebecca N. Bauer, Carrie M. Rosenberger, Yumiko Abe-Jones, Michael Adkisson, K. Mark Ansel, Saurabh Asthana, Alexander Beagle, Sharvari Bhide, Cathy Cai, Saharai Caldera, Maria Calvo, Sidney A. Carrillo, Suzanna Chak, Stephanie Christenson, Zachary Collins, Spyros Darmanis, Angela Detweiler, Catherine DeVoe, Walter Eckalbar, Jeremy Giberson, Ana Gonzalez, Gracie Gordon, Paula Hayakawa Serpa, Alejandra Jauregui, Chayse Jones, Serena Ke, Divya Kushnoor, Tasha Lea, Deanna Lee, Aleksandra Leligdowicz, Yale Liu, Salman Mahboob, Lenka Maliskova, Michael Matthay, Elizabeth McCarthy, Priscila Muñoz-Sandoval, Norma Neff, Viet Nguyen, Nishita Nigam, Randy Parada, Maira Phelps, Logan Pierce, Priya Prasad, Sadeed Rashid, Gabriella Reeder, Nicklaus Rodriguez, Bushra Samad, Andrew Schroeder, Cole Shaw, Alan Shen, Austin Sigman, Pratik Sinha, Matthew Spitzer, Sara Sunshine, Kevin Tang, Luz Torres Altamirano, Alexandra Tsitsiklis, Erden Tumurbaatar, Vaibhav Upadhyay, Alexander Whatley, Andrew Willmore, Michael Wilson, Juliane Winkler, Kristine Wong, Kimberly Yee, Michelle Yu, Mingyue Zhou, Wandi S. Zhu
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107813- (2023)
Summary: Altered myeloid inflammation and lymphopenia are hallmarks of severe infections. We identified the upregulated EN-RAGE gene program in airway and blood myeloid cells from patients with acute lung injury from SARS-CoV-2 or other causes across
Externí odkaz:
https://doaj.org/article/9fcf76e7c2d9439cbd17b0a0b7fa8d89
Autor:
Mazharul Maishan, Aartik Sarma, Lauren F. Chun, Saharai Caldera, Xiaohui Fang, Jason Abbott, Stephanie A. Christenson, Charles R. Langelier, Carolyn S. Calfee, Jeffrey E. Gotts, Michael A. Matthay
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
E-cigarette use has rapidly increased as an alternative means of nicotine delivery by heated aerosolization. Recent studies demonstrate nicotine-containing e-cigarette aerosols can have immunosuppressive and pro-inflammatory effects, but it remains u
Externí odkaz:
https://doaj.org/article/181a6dc362f34f7c934aed1613185548
Autor:
Daniel R. Calabrese, Tasha Tsao, Mélia Magnen, Colin Valet, Ying Gao, Beñat Mallavia, Jennifer J. Tian, Emily A. Aminian, Kristin M. Wang, Avishai Shemesh, Elman B. Punzalan, Aartik Sarma, Carolyn S. Calfee, Stephanie A. Christenson, Charles R. Langelier, Steven R. Hays, Jeffrey A. Golden, Lorriana E. Leard, Mary Ellen Kleinhenz, Nicholas A. Kolaitis, Rupal Shah, Aida Venado, Lewis L. Lanier, John R. Greenland, David M. Sayah, Abbas Ardehali, Jasleen Kukreja, S. Samuel Weigt, John A. Belperio, Jonathan P. Singer, Mark R. Looney
Publikováno v:
JCI Insight, Vol 7, Iss 24 (2022)
Clinical outcomes after lung transplantation, a life-saving therapy for patients with end-stage lung diseases, are limited by primary graft dysfunction (PGD). PGD is an early form of acute lung injury with no specific pharmacologic therapies. Here, w
Externí odkaz:
https://doaj.org/article/1ce137fa246e4f4d9647ad53ba99ced1
Autor:
Aartik Sarma, Stephanie A. Christenson, Ashley Byrne, Eran Mick, Angela Oliveira Pisco, Catherine DeVoe, Thomas Deiss, Rajani Ghale, Beth Shoshana Zha, Alexandra Tsitsiklis, Alejandra Jauregui, Farzad Moazed, Angela M. Detweiler, Natasha Spottiswoode, Pratik Sinha, Norma Neff, Michelle Tan, Paula Hayakawa Serpa, Andrew Willmore, K. Mark Ansel, Jennifer G. Wilson, Aleksandra Leligdowicz, Emily R. Siegel, Marina Sirota, Joseph L. DeRisi, Michael A. Matthay, COMET Consortium, Carolyn M. Hendrickson, Kirsten N. Kangelaris, Matthew F. Krummel, Prescott G. Woodruff, David J. Erle, Carolyn S. Calfee, Charles R. Langelier
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Here, the authors perform transcriptional profiling on tracheal aspirates of adults requiring mechanical ventilation for SARS-CoV2-induced acute respiratory distress syndrome (ARDS) and identify a dysregulated host response predicted to predicted to
Externí odkaz:
https://doaj.org/article/5e15572a162f473290932a34e9eb1ffa
Autor:
Benedikt Ditz, Aartik Sarma, Huib A.M. Kerstjens, Jeroen J.W. Liesker, Erik Bathoorn, Judith M. Vonk, Victor Bernal, Peter Horvatovich, Victor Guryev, Saharai Caldera, Chaz Langelier, Alen Faiz, Stephanie A. Christenson, Maarten van den Berge
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Introduction Continuing inhaled corticosteroid (ICS) use does not benefit all patients with COPD, yet it is difficult to determine which patients may safely sustain ICS withdrawal. Although eosinophil levels can facilitate this decision, better bioma
Externí odkaz:
https://doaj.org/article/5dbef8c341894c82ae1c0603e55e69f3
Autor:
Katherine D. Wick, Xiaohui Fang, Mazharul Maishan, Shotaro Matsumoto, Natasha Spottiswoode, Aartik Sarma, Camille Simoneau, Manisha Khakoo, Chaz Langelier, Carolyn S. Calfee, Jeffrey E. Gotts, Michael A. Matthay
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(2)
Electronic cigarettes (e-cigarettes) are designed to simulate combustible cigarette smoking and to aid in smoking cessation. Although the number of e-cigarette users has been increasing, the potential health impacts and biological effects of e-cigare
Autor:
Yue Chen, Antonio Gomez, Kevin L. Delucchi, J. Brennan McNeil, Michael A. Matthay, Nancy E. Wickersham, Carolyn S. Calfee, Kathleen D. Liu, Aleksandra Leligdowicz, Serena Ke, Kirsten N. Kangelaris, Hanjing Zhuo, Aartik Sarma, Lorraine B. Ware, Pratik Sinha, Alejandra Jauregui, Kathryn Vessel, Chunxue Wang, Jason Abbott, Carolyn M. Hendrickson
Publikováno v:
Thorax. 77:13-21
RationaleUsing latent class analysis (LCA), two subphenotypes of acute respiratory distress syndrome (ARDS) have consistently been identified in five randomised controlled trials (RCTs), with distinct biological characteristics, divergent outcomes an
Autor:
Katrina Kalantar, Lucile Neyton, Mazin Abdelghany, Eran Mick, Alejandra Jauregui, Saharai Caldera, Paula Hayakawa Serpa, Rajani Ghale, Jack Albright, Aartik Sarma, Alexandra Tsitsiklis, Aleksandra Leligdowicz, Stephanie Christenson, Kathleen Liu, Kirsten Kangelaris, Carolyn Hendrickson, Pratik Sinha, Antonio Gomez, Norma Neff, Angela Pisco, Sarah Doernberg, Joseph L. Derisi, Michael A. Matthay, Carolyn S. Calfee, Charles R. Langelier
Sepsis is a leading cause of death, and improved approaches for disease diagnosis and detection of etiologic pathogens are urgently needed. Here, we carried out integrated host and pathogen metagenomic next generation sequencing (mNGS) of whole blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d09ad2469135e9d28eb184cfcdf5c4d
https://doi.org/10.1101/2022.07.16.22277700
https://doi.org/10.1101/2022.07.16.22277700
Autor:
Manoj Maddali, Beth Shoshana Zha, Aartik Sarma, Eran Mick, Lucile Neyton, Aleksandra Leligdowicz, Angela Oliveira Pisco
BackgroundTwo molecular phenotypes of the acute respiratory distress syndrome (ARDS) with divergent clinical trajectories and responses to therapy have been identified. Classification as “hyperinflammatory” or “hypoinflammatory” depends on pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b22c8836a9c962080a5f6dbb6adc88f
https://doi.org/10.1101/2022.03.31.22272425
https://doi.org/10.1101/2022.03.31.22272425