Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Aarti V. Shah"'
Autor:
Christopher M. Schafer, Silvia Martin-Almedina, Katarzyna Kurylowicz, Neil Dufton, Lourdes Osuna-Almagro, Meng-Ling Wu, Charmain F. Johnson, Aarti V. Shah, Dorian O. Haskard, Andrianna Buxton, Erika Willis, Kate Wheeler, Sean Turner, Magdalena Chlebicz, Rizaldy P. Scott, Susan Kovats, Audrey Cleuren, Graeme M. Birdsey, Anna M. Randi, Courtney T. Griffin
Publikováno v:
bioRxiv
BackgroundDuring infectious diseases, pro-inflammatory cytokines transiently destabilize interactions between adjacent vascular endothelial cells (ECs) to facilitate the passage of immune molecules and cells into tissues. However, in the lung the res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526ae34af15f04eccb276895f65dccd1
https://doi.org/10.1101/2023.02.08.527788
https://doi.org/10.1101/2023.02.08.527788
Autor:
Martin R. Bennett, Aarti V. Shah
Publikováno v:
European Journal of Pharmacology. 816:116-128
A decline in the function of the macro- and micro-vasculature occurs with ageing. DNA damage also accumulates with ageing, and thus DNA damage and repair have important roles in physiological ageing. Considerable evidence also supports a crucial role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760144981f59aab70251806f6610e269
https://doi.org/10.1016/j.ejphar.2017.03.050
https://doi.org/10.1016/j.ejphar.2017.03.050
Autor:
Viktoria, Kalna, Youwen, Yang, Claire R, Peghaire, Karen, Frudd, Rebecca, Hannah, Aarti V, Shah, Lourdes, Osuna Almagro, Joseph J, Boyle, Berthold, Göttgens, Jorge, Ferrer, Anna M, Randi, Graeme M, Birdsey
Publikováno v:
Circulation Research
Supplemental Digital Content is available in the text.
Rationale: The ETS (E-26 transformation-specific) transcription factor ERG (ETS-related gene) is essential for endothelial homeostasis, driving expression of lineage genes and repressing pro
Rationale: The ETS (E-26 transformation-specific) transcription factor ERG (ETS-related gene) is essential for endothelial homeostasis, driving expression of lineage genes and repressing pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38c7dd76a51c41e597ba42abd3dc682d
https://pubmed.ncbi.nlm.nih.gov/30892142
https://pubmed.ncbi.nlm.nih.gov/30892142
Autor:
Jason M, Tarkin, Francis R, Joshi, Nicholas R, Evans, Mohammed M, Chowdhury, Nichola L, Figg, Aarti V, Shah, Lakshi T, Starks, Abel, Martin-Garrido, Roido, Manavaki, Emma, Yu, Rhoda E, Kuc, Luigi, Grassi, Roman, Kreuzhuber, Myrto A, Kostadima, Mattia, Frontini, Peter J, Kirkpatrick, Patrick A, Coughlin, Deepa, Gopalan, Tim D, Fryer, John R, Buscombe, Ashley M, Groves, Willem H, Ouwehand, Martin R, Bennett, Elizabeth A, Warburton, Anthony P, Davenport, James H F, Rudd
Publikováno v:
Journal of the American College of Cardiology. 69(14)
Inflammation drives atherosclerotic plaque rupture. Although inflammation can be measured using fluorine-18-labeled fluorodeoxyglucose positron emission tomography ([This study tested the efficacy of gallium-68-labeled DOTATATE (We confirmedTarget SS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cca60bda07a9277730fd3d0249f4c4b3
https://pubmed.ncbi.nlm.nih.gov/28385307
https://pubmed.ncbi.nlm.nih.gov/28385307
Publikováno v:
Vascular Pharmacology
Over the last few years, the ETS transcription factor ERG has emerged as a major regulator of endothelial function. Multiple studies have shown that ERG plays a crucial role in promoting angiogenesis and vascular stability during development and afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8bebc2cd63cb2f29a7a24388631784b
https://pubmed.ncbi.nlm.nih.gov/27208692
https://pubmed.ncbi.nlm.nih.gov/27208692
Publikováno v:
Atherosclerosis Supplements. 32:5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb2e4dbca2542765c49307000676ced2
https://doi.org/10.1016/j.atherosclerosissup.2018.04.016
https://doi.org/10.1016/j.atherosclerosissup.2018.04.016
Autor:
Martin R. Bennett, Nicholas R. Evans, Lakshi T Starks, Francis R. Joshi, Abel Martin-Garrido, John R Buscombe, Rhoda E. Kuc, Jason M. Tarkin, Mattia Frontini, Willem H. Ouwehand, Emma Yu, Roman Kreuzhuber, Patrick A. Coughlin, Deepa Gopalan, Mohammed M. Chowdhury, Peter J. Kirkpatrick, Tim D. Fryer, Roido Manavaki, James H.F. Rudd, Aarti V. Shah, Nichola Figg, Ashley M. Groves, Luigi Grassi, Elizabeth A. Warburton, Anthony P. Davenport, Myrto Kostadima
Publikováno v:
Heart. 103:A151.2-A152
Background Inflammation drives atherosclerotic plaque rupture underlying most clinical events. While inflammation can be measured using 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET), 18F-FDG lacks cell-specificity and is unreliable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a514a7e838c86262ac43aca32830f57
https://doi.org/10.1136/heartjnl-2017-311726.235
https://doi.org/10.1136/heartjnl-2017-311726.235
Autor:
Nicola H. Dryden, Graeme M. Birdsey, Marketa Zvelebil, Justin C. Mason, Anna M. Randi, Rebecca Hannah, Matthew D. Hall, Anne J. Ridley, Aarti V. Shah, Berthold Göttgens, Dorian O. Haskard, Madeline Parsons
Publikováno v:
Blood. 119(3)
The endothelial ETS transcription factor Erg plays an important role in homeostasis and angiogenesis by regulating many endothelial functions including survival and junction stability. Here we show that Erg regulates endothelial cell (EC) migration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488e90490ef5326cdc6d11f22f469947
https://pubmed.ncbi.nlm.nih.gov/22117042
https://pubmed.ncbi.nlm.nih.gov/22117042
Autor:
Anna M. Randi, Bertie Gottgens, Justin C. Mason, Marketa Zvelebil, Graeme M. Birdsey, Rebecca Hannah, Anne J. Ridley, Nicky H. Dryden, Madeline Parsons, Aarti V. Shah
Publikováno v:
Vascular Pharmacology. 56:348-349
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5530dfe747abea90c7a17cea1e916f7a
https://doi.org/10.1016/j.vph.2011.08.120
https://doi.org/10.1016/j.vph.2011.08.120
Autor:
Neil Dufton, Kairbaan Hodivala-Dilke, Louise E. Reynolds, Samia Taufiq Khan, Berthold Göttgens, Ralf H. Adams, Anna M. Randi, Aarti V. Shah, Holger Gerhardt, Irene M. Aspalter, Lourdes Osuna Almagro, Graeme M. Birdsey, Elisabetta Dejana, Justin C. Mason, Youwen Yang
Publikováno v:
Developmental Cell
Summary Blood vessel stability is essential for embryonic development; in the adult, many diseases are associated with loss of vascular integrity. The ETS transcription factor ERG drives expression of VE-cadherin and controls junctional integrity. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f93f38aa169c6585ddebebf21460b49