Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aarti Jashnani"'
Autor:
SJ J. Diong, Aarti Jashnani, Andrew W. Drake, Christine Bee, Felix Findeisen, Gavin Dollinger, Feng Wang, Arvind Rajpal, Pavel Strop, Peter S. Lee
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTThe clinical successes of immune checkpoint blockade have invigorated efforts to activate T cell-mediated responses against cancer. Targeting members of the PVR family, consisting of inhibitory receptors TIGIT, CD96, and CD112R, has been an a
Externí odkaz:
https://doaj.org/article/a87135d2ea7c4bbf994e640a49d231a7
Autor:
Peter S. Lee, Bryant Chau, Ishita Barman, Christine Bee, Aarti Jashnani, Jason M. Hogan, Barbara Aguilar, Gavin Dollinger, Arvind Rajpal, Pavel Strop
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
The molecular interactions of mouse CD96 to CD155 ligand and to two surrogate antibodies have been investigated. Biophysical and structural studies demonstrate that CD96 forms a homodimer but assembles as 1:1 heterodimeric complexes with CD155 or wit
Externí odkaz:
https://doaj.org/article/66366a7e8eaa4fb482911e34fd1d5fab
Autor:
Sayumi Yamazoe, Srikanth Kotapati, Jason M. Hogan, Sean M. West, Xiaodi A. Deng, SJ Diong, Jaren Arbanas, Thien Anh Nguyen, Aarti Jashnani, Diksha Gupta, Arvind Rajpal, Gavin Dollinger, Pavel Strop
Publikováno v:
Bioconjugate Chemistry. 33:576-585
Autor:
Gavin Dollinger, Jason M. Hogan, Barbara Aguilar, Arvind Rajpal, Ishita Barman, Aarti Jashnani, Peter Sung Keun Lee, Christine Bee, Pavel Strop, Bryant Chau
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The molecular interactions of mouse CD96 to CD155 ligand and to two surrogate antibodies have been investigated. Biophysical and structural studies demonstrate that CD96 forms a homodimer but assembles as 1:1 heterodimeric complexes with CD155 or wit
Autor:
Madhura Deshpande, Hongwu Xu, Dharam Thakkar, Aarti Jashnani, Gavin Dollinger, Srikanth Kotapati
Publikováno v:
Bioanalysis. 13(11)
Ligand-binding assay (LBA) and LC–MS have been the preferred bioanalytical techniques for the quantitation and biotransformation assessment of various therapeutic modalities. This review provides an overview of the applications of LBA, LC–MS/MS a
Autor:
Arvind Rajpal, Sayumi Yamazoe, Aarti Jashnani, Srikanth Kotapati, Gavin Dollinger, Pavel Strop, Madhura Deshpande
Publikováno v:
Analytical chemistry. 93(13)
Traditionally the biotransformation of antibody drug conjugates (ADCs) has been evaluated by affinity capture on streptavidin magnetic beads coated with a biotinylated capture reagent. To reduce the complexity of the analyte, the affinity captured AD
Autor:
Suhaas Aluri, Sarah F. Hamm-Alvarez, Aarti Jashnani, Pang-Yu Hsueh, Wan Wang, Gordon W. Laurie, Frances Yarber, J. Andrew MacKay, Robert L. McKown, Joshua A. Gustafson
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 199
Millions of Americans suffer from dry eye disease, and there are few effective therapies capable of treating these patients. A decade ago, an abundant protein component of human tears was discovered and named lacritin (Lacrt). Lacrt has prosecretory