Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Aaron denDekker"'
Autor:
Sonya J. Wolf, Christopher O. Audu, Amrita Joshi, Aaron denDekker, William J. Melvin, Frank M. Davis, Xianying Xing, Rachael Wasikowski, Lam C. Tsoi, Steven L. Kunkel, Johann E. Gudjonsson, Mary X. O’Riordan, J. Michelle Kahlenberg, Katherine A. Gallagher
Publikováno v:
JCI Insight, Vol 7, Iss 9 (2022)
Wound repair following acute injury requires a coordinated inflammatory response. Type I IFN signaling is important for regulating the inflammatory response after skin injury. IFN-κ, a type I IFN, has recently been found to drive skin inflammation i
Externí odkaz:
https://doaj.org/article/eca6cf178c67407eb93d2292893b3a0c
Autor:
Frank M. Davis, Lam C. Tsoi, Rachael Wasikowski, Aaron denDekker, Amrita Joshi, Carol Wilke, Hongping Deng, Sonya Wolf, Andrea Obi, Steven Huang, Allison C. Billi, Scott Robinson, Jay Lipinski, William J. Melvin, Christopher O. Audu, Stephan Weidinger, Steven L. Kunkel, Andrew Smith, Johann E. Gudjonsson, Bethany B. Moore, Katherine A. Gallagher
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2020)
Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype and is critical for normal tissue repair following injury. Evidence suggests that epigeneti
Externí odkaz:
https://doaj.org/article/f96a2c186aa440dc9e0a0bd22363cca4
Autor:
Aaron denDekker, Frank Davis, Andrew Kimball, Matthew Schaller, Amrita Joshi, Ronald Allen, Katherine Gallagher
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 15-15 (2021)
ABSTRACT IMPACT: Our data reveal a histone modifying enzyme involved in regulating inflammation that may be a novel target for treating non-healing diabetic wounds. OBJECTIVES/GOALS: We investigate molecular mechanisms that regulate the inflammatory
Externí odkaz:
https://doaj.org/article/24cadedcddf541798ad547763b2e04ea
Autor:
Jennifer R Bermick, Priya Issuree, Aaron denDekker, Katherine A Gallagher, Donna Santillan, Steven Kunkel, Nicholas Lukacs, Matthew Schaller
Publikováno v:
Immunology & Cell Biology. 100:562-579
Neonatal CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcc941fdb0c8a99a8854ce361e0f7c7
https://doi.org/10.1111/imcb.12561
https://doi.org/10.1111/imcb.12561
Autor:
Zhenhua Zou, Bo Zhou, Aaron denDekker, Qiang Li, Yali Dou, Rajesh C. Rao, Sean Hou, Fengbiao Mao, Jie Liu, Yuanhao Huang, Jing Xu
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 465-480.e6 (2020)
Cell reports
Cell reports
SUMMARY How ubiquitous transcription factors (TFs) coordinate temporal inputs from broadly expressed epigenetic factors to control cell fate remains poorly understood. Here, we uncover a molecular relationship between p53, an abundant embryonic TF, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa9add1293f95c30f292276a1df2eb2
http://www.sciencedirect.com/science/article/pii/S2211124719316961
http://www.sciencedirect.com/science/article/pii/S2211124719316961
Autor:
Emily Barrett, Kevin Mangum, Sonya J. Wolf, Frank M. Davis, Andrea T. Obi, Christopher O. Audu, Xiaofeng Zhou, Monica Bame, Bethany B. Moore, Aaron denDekker, William J. Melvin, Sriganesh B Sharma, Katherine A. Gallagher, Amrita Joshi, Steven L. Kunkel, Alex Ruan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The COVID-19 pandemic has disproportionately affected patients with comorbidities, namely, obesity and type 2 diabetes. Macrophages (Mφs) are a key innate immune cell primarily responsible for the harmful, hyperinflammatory “cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24a88b7631df87319ba4fa03f0fb832
https://pubmed.ncbi.nlm.nih.gov/34479991
https://pubmed.ncbi.nlm.nih.gov/34479991
Autor:
Sonya J. Wolf, Christopher O. Audu, Amrita Joshi, Aaron denDekker, William J. Melvin, Frank M. Davis, Xianying Xing, Rachael Wasikowski, Lam C. Tsoi, Steven L. Kunkel, Johann E. Gudjonsson, Mary X. O’Riordan, J. Michelle Kahlenberg, Katherine A. Gallagher
Publikováno v:
JCI insight. 7(9)
Wound repair following acute injury requires a coordinated inflammatory response. Type I IFN signaling is important for regulating the inflammatory response after skin injury. IFN-κ, a type I IFN, has recently been found to drive skin inflammation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f400f97a4c9ad8a69e2be99311289136
https://pubmed.ncbi.nlm.nih.gov/35358091
https://pubmed.ncbi.nlm.nih.gov/35358091
Autor:
Katherine A. Gallagher, Ronald M. Allen, Aaron denDekker, Andrew Kimball, Steven L. Kunkel, Dylan Nysz, Andrea T. Obi, Kanakadurga Singer, Anna Boniakowski, Frank M. Davis, Amrita Joshi, Peter K. Henke, Bethany B. Moore
Publikováno v:
The Journal of Immunology. 202:1777-1785
Myeloid cells are critical for orchestrating regulated inflammation during wound healing. TLRs, particularly TLR4, and its downstream-signaling MyD88 pathway play an important role in regulating myeloid-mediated inflammation. Because an initial infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13366d370b2af6720b408f05979dd06c
https://doi.org/10.4049/jimmunol.1801258
https://doi.org/10.4049/jimmunol.1801258
Autor:
Amrita Joshi, Katherine A. Gallagher, Steven L. Kunkel, Alan Daugherty, Frank M. Davis, Hong Lu, Bethany B. Moore, Christopher O. Audu, Aaron denDekker, William J. Melvin, Andrea T. Obi, Allison C. Billi, Xianying Xing, Lam C. Tsoi, Johann E. Gudjonsson, Rachael Wasikowski, Sonya J. Wolf
Publikováno v:
The Journal of Experimental Medicine
Abdominal aortic aneurysms (AAAs) are a life-threatening disease characterized by macrophage infiltration contributing to pathological vascular remodeling. Herein, we demonstrate that the histone demethylase JMJD3 is a critical regulator of inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31677b53108946d72e2316951e164cc
http://europepmc.org/articles/PMC8008365
http://europepmc.org/articles/PMC8008365
Autor:
Amrita Joshi, Christopher O. Audu, Katherine A. Gallagher, Aaron denDekker, Sriganesh B Sharma, William J. Melvin
Publikováno v:
Journal of the American College of Surgeons. 233:S325-S326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d574929960279fd9ff376a7618e3d2d
https://doi.org/10.1016/j.jamcollsurg.2021.07.677
https://doi.org/10.1016/j.jamcollsurg.2021.07.677