Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aaron Y. Mochizuki"'
Autor:
Alexander H. Lee, Lu Sun, Aaron Y. Mochizuki, Jeremy G. Reynoso, Joey Orpilla, Frances Chow, Jenny C. Kienzler, Richard G. Everson, David A. Nathanson, Steven J. Bensinger, Linda M. Liau, Timothy Cloughesy, Willy Hugo, Robert M. Prins
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Immune-checkpoint blockade has shown limited benefits in patients with glioblastoma. To understand how the composition of the tumor immune microenvironment might limit clinical responses, here the authors present a high dimensional profiling of the i
Externí odkaz:
https://doaj.org/article/bc4276916a1e42c19b71f6a03a3eba26
Autor:
Jane E. Minturn, Aaron Y. Mochizuki, Sonia Partap, Jean B. Belasco, Beverly J. Lange, Yimei Li, Peter C. Phillips, Iris C. Gibbs, Paul G. Fisher, Michael J. Fisher, Anna J. Janss
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeMedulloblastoma is one of the most common malignant brain tumors in children. To date, the treatment of average-risk (non-metastatic, completely resected) medulloblastoma includes craniospinal radiation therapy and adjuvant chemotherapy. Moder
Externí odkaz:
https://doaj.org/article/fb2525400b14444695010cc410e86020
Autor:
Geoffrey C. Owens, Alejandro J. Garcia, Aaron Y. Mochizuki, Julia W. Chang, Samuel D. Reyes, Noriko Salamon, Robert M. Prins, Gary W. Mathern, Aria Fallah
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Brain-infiltrating lymphocytes (BILs) were isolated from resected brain tissue from 10 pediatric epilepsy patients who had undergone surgery for Hemimegalencephaly (HME) (n = 1), Tuberous sclerosis complex (TSC) (n = 2), Focal cortical dysplasia (FCD
Externí odkaz:
https://doaj.org/article/06c656b595404e0ba88e48cb09707739
Autor:
Derek A. Wainwright, David H. Munn, George C. Prendergast, Ursula Grohmann, Judith Campisi, Graham Pawelec, Changyou Zhou, Min Wei, Craig Horbinski, Rimas V. Lukas, Karan Dixit, Jeffrey J. Raizer, Priya Kumthekar, Robert M. Prins, Aaron Y. Mochizuki, Leonidas C. Platanias, Joseph R. Podojil, Jennifer D. Wu, Bin Zhang, Masha Kocherginsky, Jiahui Xu, April Bell, Kristen L. Lauing, Lijie Zhai, Erik Ladomersky
Supplemental Figure 5. Confirmation of gut microbiota depletion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c406912952ef4df99e3435065c2d59
https://doi.org/10.1158/1078-0432.22477865.v1
https://doi.org/10.1158/1078-0432.22477865.v1
Autor:
Derek A. Wainwright, David H. Munn, George C. Prendergast, Ursula Grohmann, Judith Campisi, Graham Pawelec, Changyou Zhou, Min Wei, Craig Horbinski, Rimas V. Lukas, Karan Dixit, Jeffrey J. Raizer, Priya Kumthekar, Robert M. Prins, Aaron Y. Mochizuki, Leonidas C. Platanias, Joseph R. Podojil, Jennifer D. Wu, Bin Zhang, Masha Kocherginsky, Jiahui Xu, April Bell, Kristen L. Lauing, Lijie Zhai, Erik Ladomersky
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3350aa320ffb492921fca7f272bb58
https://doi.org/10.1158/1078-0432.22477883
https://doi.org/10.1158/1078-0432.22477883
Autor:
Derek A. Wainwright, David H. Munn, George C. Prendergast, Ursula Grohmann, Judith Campisi, Graham Pawelec, Changyou Zhou, Min Wei, Craig Horbinski, Rimas V. Lukas, Karan Dixit, Jeffrey J. Raizer, Priya Kumthekar, Robert M. Prins, Aaron Y. Mochizuki, Leonidas C. Platanias, Joseph R. Podojil, Jennifer D. Wu, Bin Zhang, Masha Kocherginsky, Jiahui Xu, April Bell, Kristen L. Lauing, Lijie Zhai, Erik Ladomersky
Supplemental Figure 6. Characterization of the potent clinical-grade IDO enzyme inhibitor, BGB-7204.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173f2030ce97d7e239f622881e8045c6
https://doi.org/10.1158/1078-0432.22477859
https://doi.org/10.1158/1078-0432.22477859
Autor:
Derek A. Wainwright, David H. Munn, George C. Prendergast, Ursula Grohmann, Judith Campisi, Graham Pawelec, Changyou Zhou, Min Wei, Craig Horbinski, Rimas V. Lukas, Karan Dixit, Jeffrey J. Raizer, Priya Kumthekar, Robert M. Prins, Aaron Y. Mochizuki, Leonidas C. Platanias, Joseph R. Podojil, Jennifer D. Wu, Bin Zhang, Masha Kocherginsky, Jiahui Xu, April Bell, Kristen L. Lauing, Lijie Zhai, Erik Ladomersky
Supplemental Figure 1. Inclusion and exclusion criteria for the analysis of human subjects diagnosed with glioblastoma (GBM).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f9d29ef6df89e207ca831ea2913f78
https://doi.org/10.1158/1078-0432.22477877.v1
https://doi.org/10.1158/1078-0432.22477877.v1
Autor:
Derek A. Wainwright, David H. Munn, George C. Prendergast, Ursula Grohmann, Judith Campisi, Graham Pawelec, Changyou Zhou, Min Wei, Craig Horbinski, Rimas V. Lukas, Karan Dixit, Jeffrey J. Raizer, Priya Kumthekar, Robert M. Prins, Aaron Y. Mochizuki, Leonidas C. Platanias, Joseph R. Podojil, Jennifer D. Wu, Bin Zhang, Masha Kocherginsky, Jiahui Xu, April Bell, Kristen L. Lauing, Lijie Zhai, Erik Ladomersky
Supplemental Figure 7. Bioluminescent imaging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ff338a1f2267cf30e7c747c5d6dfdb
https://doi.org/10.1158/1078-0432.22477856
https://doi.org/10.1158/1078-0432.22477856
Autor:
Derek A. Wainwright, David H. Munn, George C. Prendergast, Ursula Grohmann, Judith Campisi, Graham Pawelec, Changyou Zhou, Min Wei, Craig Horbinski, Rimas V. Lukas, Karan Dixit, Jeffrey J. Raizer, Priya Kumthekar, Robert M. Prins, Aaron Y. Mochizuki, Leonidas C. Platanias, Joseph R. Podojil, Jennifer D. Wu, Bin Zhang, Masha Kocherginsky, Jiahui Xu, April Bell, Kristen L. Lauing, Lijie Zhai, Erik Ladomersky
Supplemental Figure 2. Glioblastoma patient overall survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fefcecd01f8809d462af42fbf334f0f
https://doi.org/10.1158/1078-0432.22477874.v1
https://doi.org/10.1158/1078-0432.22477874.v1
Autor:
Derek A. Wainwright, David H. Munn, George C. Prendergast, Ursula Grohmann, Judith Campisi, Graham Pawelec, Changyou Zhou, Min Wei, Craig Horbinski, Rimas V. Lukas, Karan Dixit, Jeffrey J. Raizer, Priya Kumthekar, Robert M. Prins, Aaron Y. Mochizuki, Leonidas C. Platanias, Joseph R. Podojil, Jennifer D. Wu, Bin Zhang, Masha Kocherginsky, Jiahui Xu, April Bell, Kristen L. Lauing, Lijie Zhai, Erik Ladomersky
Purpose:Wild-type isocitrate dehydrogenase–expressing glioblastoma (GBM) is the most common and aggressive primary brain tumor with a median age at diagnosis of ≥65 years. It accounts for approximately 90% of all GBMs and has a median overall sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615ba5f4948cb02a75eddfd344fcbc84
https://doi.org/10.1158/1078-0432.c.6529778.v1
https://doi.org/10.1158/1078-0432.c.6529778.v1