Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Aaron W. James"'
Autor:
Manyu Zhu, Ji-Hye Yea, Zhao Li, Qizhi Qin, Mingxin Xu, Xin Xing, Stefano Negri, Mary Archer, Monisha Mittal, Benjamin Levi, Aaron W. James
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Heterotopic ossification (HO) is a pathological process that commonly arises following severe polytrauma, characterized by the anomalous differentiation of mesenchymal progenitor cells and resulting in the formation of ectopic bone in non-sk
Externí odkaz:
https://doaj.org/article/9fda61dc21de4fc3a9bd8121078b577e
Autor:
Yiyun Wang, Qizhi Qin, Ziyi Wang, Stefano Negri, Takashi Sono, Robert J. Tower, Zhao Li, Xin Xing, Mary Archer, Neelima Thottappillil, Manyu Zhu, Allister Suarez, Deok-Ho Kim, Tyler Harvey, Chen-Ming Fan, Aaron W. James
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-15 (2024)
Abstract The regeneration of the mammalian skeleton’s craniofacial bones necessitates the action of intrinsic and extrinsic inductive factors from multiple cell types, which function hierarchically and temporally to control the differentiation of o
Externí odkaz:
https://doaj.org/article/5800b8472f1d49b1972a215f61072512
Autor:
Heeseog Kang, Amy L. Strong, Yuxiao Sun, Lei Guo, Conan Juan, Alec C. Bancroft, Ji Hae Choi, Chase A. Pagani, Aysel A. Fernandes, Michael Woodard, Juhoon Lee, Sowmya Ramesh, Aaron W. James, David Hudson, Kevin N. Dalby, Lin Xu, Robert J. Tower, Benjamin Levi
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract While hypoxic signaling has been shown to play a role in many cellular processes, its role in metabolism-linked extracellular matrix (ECM) organization and downstream processes of cell fate after musculoskeletal injury remains to be determin
Externí odkaz:
https://doaj.org/article/bbe26278c92c4c7694b18c1d110b314f
Autor:
Neda Vishlaghi, Lei Guo, Danielle Griswold-Wheeler, Yuxiao Sun, Cori Booker, Janna L. Crossley, Alec C. Bancroft, Conan Juan, Sneha Korlakunta, Sowmya Ramesh, Chase A. Pagani, Lin Xu, Aaron W. James, Robert J. Tower, Michael Dellinger, Benjamin Levi
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114049- (2024)
Summary: Heterotopic ossification (HO) is a challenging condition that occurs after musculoskeletal injury and is characterized by the formation of bone in non-skeletal tissues. While the effect of HO on blood vessels is well established, little is k
Externí odkaz:
https://doaj.org/article/380f2e9c21d64906ac902f08059b24b6
Autor:
Ji-Hye Yea, Mario Gomez-Salazar, Sharon Onggo, Zhao Li, Neelima Thottappillil, Masnsen Cherief, Stefano Negri, Xin Xing, Qizhi Qin, Robert Joel Tower, Chen-Ming Fan, Benjamin Levi, Aaron W. James
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Heterotopic ossification (HO) is a pathological process resulting in aberrant bone formation and often involves synovial lined tissues. During this process, mesenchymal progenitor cells undergo endochondral ossification. Nonetheless, the spe
Externí odkaz:
https://doaj.org/article/812a270dd3d2487c96d53369d4a97c5e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/64153677fac04f4cbb835e20f6f438a4
Autor:
Qizhi Qin, Sowmya Ramesh, Mario Gomez-Salazar, Lingke Zhong, Masnsen Cherief, Aniket Pratapneni, Carol D. Morris, Edward F. McCarthy, Xinli Zhang, Aaron W. James
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-13 (2023)
Abstract Improved treatment strategies for sarcoma rely on clarification of the molecular mediators of disease progression. Recently, we reported that the secreted glycoprotein NELL-1 modulates osteosarcoma (OS) disease progression in part via alteri
Externí odkaz:
https://doaj.org/article/e9536b007196499980138c7321a006ae
Autor:
Ginny Ching-Yun Hsu, Yiyun Wang, Amy Z. Lu, Mario A. Gomez-Salazar, Jiajia Xu, Dongqing Li, Carolyn Meyers, Stefano Negri, Sintawat Wangsiricharoen, Kristen Broderick, Bruno Peault, Carol Morris, Aaron W. James
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Pericytes are multipotent mesenchymal precursor cells that demonstrate tissue-specific properties. In this study, by comparing human adipose tissue– and periosteum-derived pericyte microarrays, we identified T cell lymphoma invasion and metastasis
Externí odkaz:
https://doaj.org/article/e2026f2d5316443c93268094de35014d
Autor:
Qizhi Qin, Mario Gomez-Salazar, Masnsen Cherief, Chase A. Pagani, Seungyong Lee, Charles Hwang, Robert J. Tower, Sharon Onggo, Yuxiao Sun, Abhinav Piplani, Zhao Li, Sowmya Ramesh, Thomas L. Clemens, Benjamin Levi, Aaron W. James
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract The functional interdependence of nerves and blood vessels is a well-established concept during tissue morphogenesis, yet the role of neurovascular coupling in proper and aberrant tissue repair is an emerging field of interest. Here, we soug
Externí odkaz:
https://doaj.org/article/ef7282b1693d42e9be9a1347385481ec
Autor:
Jiajia Xu, Yiyun Wang, Zhu Li, Ye Tian, Zhao Li, Amy Lu, Ching-Yun Hsu, Stefano Negri, Cammy Tang, Robert J. Tower, Carol Morris, Aaron W. James
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract The outer coverings of the skeleton, which is also known as the periosteum, are arranged in concentric layers and act as a reservoir for tissue-specific bone progenitors. The cellular heterogeneity within this tissue depot is being increasin
Externí odkaz:
https://doaj.org/article/288858cb59cb434d84de9ff06d11d1b3