Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Aaron W James"'
Autor:
Jiajia Xu, Yiyun Wang, Ching-Yun Hsu, Stefano Negri, Robert J Tower, Yongxing Gao, Ye Tian, Takashi Sono, Carolyn A Meyers, Winters R Hardy, Leslie Chang, Shuaishuai Hu, Nusrat Kahn, Kristen Broderick, Bruno Péault, Aaron W James
Publikováno v:
eLife, Vol 9 (2020)
Tissue resident mesenchymal stem/stromal cells (MSCs) occupy perivascular spaces. Profiling human adipose perivascular mesenchyme with antibody arrays identified 16 novel surface antigens, including endolysosomal protein CD107a. Surface CD107a expres
Externí odkaz:
https://doaj.org/article/4b6fc769da414823962e1b24d2495680
Autor:
Yiyun Wang, Qizhi Qin, Ziyi Wang, Stefano Negri, Takashi Sono, Robert J. Tower, Zhao Li, Xin Xing, Mary Archer, Neelima Thottappillil, Manyu Zhu, Allister Suarez, Deok-Ho Kim, Tyler Harvey, Chen-Ming Fan, Aaron W. James
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-15 (2024)
Abstract The regeneration of the mammalian skeleton’s craniofacial bones necessitates the action of intrinsic and extrinsic inductive factors from multiple cell types, which function hierarchically and temporally to control the differentiation of o
Externí odkaz:
https://doaj.org/article/5800b8472f1d49b1972a215f61072512
Autor:
Aaron W James, Xinli Zhang, Mihaela Crisan, Winters R Hardy, Pei Liang, Carolyn A Meyers, Sonja Lobo, Venu Lagishetty, Martin K Childers, Greg Asatrian, Catherine Ding, Yu-Hsin Yen, Erin Zou, Kang Ting, Bruno Peault, Chia Soo
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177308 (2017)
For over 15 years, human subcutaneous adipose tissue has been recognized as a rich source of tissue resident mesenchymal stem/stromal cells (MSC). The isolation of perivascular progenitor cells from human adipose tissue by a cell sorting strategy was
Externí odkaz:
https://doaj.org/article/7f92defcf79f47299db51499cc6b947e
Autor:
Heeseog Kang, Amy L. Strong, Yuxiao Sun, Lei Guo, Conan Juan, Alec C. Bancroft, Ji Hae Choi, Chase A. Pagani, Aysel A. Fernandes, Michael Woodard, Juhoon Lee, Sowmya Ramesh, Aaron W. James, David Hudson, Kevin N. Dalby, Lin Xu, Robert J. Tower, Benjamin Levi
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract While hypoxic signaling has been shown to play a role in many cellular processes, its role in metabolism-linked extracellular matrix (ECM) organization and downstream processes of cell fate after musculoskeletal injury remains to be determin
Externí odkaz:
https://doaj.org/article/bbe26278c92c4c7694b18c1d110b314f
Autor:
Neda Vishlaghi, Lei Guo, Danielle Griswold-Wheeler, Yuxiao Sun, Cori Booker, Janna L. Crossley, Alec C. Bancroft, Conan Juan, Sneha Korlakunta, Sowmya Ramesh, Chase A. Pagani, Lin Xu, Aaron W. James, Robert J. Tower, Michael Dellinger, Benjamin Levi
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114049- (2024)
Summary: Heterotopic ossification (HO) is a challenging condition that occurs after musculoskeletal injury and is characterized by the formation of bone in non-skeletal tissues. While the effect of HO on blood vessels is well established, little is k
Externí odkaz:
https://doaj.org/article/380f2e9c21d64906ac902f08059b24b6
Publikováno v:
Frontiers in Physiology, Vol 4 (2013)
During craniofacial development, the Hedgehog (HH) signaling pathway is essential for mesodermal tissue patterning and differentiation. The Hedgehog family consists of three protein ligands: Sonic Hedgehog (SHH), Indian Hedgehog (IHH), and Desert Hed
Externí odkaz:
https://doaj.org/article/9624f0b644554db9bc94c17727ea9e20
Autor:
Emily R Nelson, Benjamin Levi, Michael Sorkin, Aaron W James, Karen J Liu, Natalina Quarto, Michael T Longaker
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25847 (2011)
The function of Glycogen Synthase Kinases 3β (GSK-3β) has previously been shown to be necessary for normal secondary palate development. Using GSK-3ß null mouse embryos, we examine the potential coordinate roles of Wnt and Hedgehog signaling on pa
Externí odkaz:
https://doaj.org/article/7aedd21601c148abb867c459d322a8f6
Autor:
Benjamin Levi, Aaron W James, Emily R Nelson, Dean Vistnes, Benjamin Wu, Min Lee, Ankur Gupta, Michael T Longaker
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11177 (2010)
Human adipose-derived stromal cells (hASCs) represent a multipotent cell stromal cell type with proven capacity to differentiate along an osteogenic lineage. This suggests that they may be used to heal defects of the craniofacial or appendicular skel
Externí odkaz:
https://doaj.org/article/c4316647ed4d4b1889c978ca90b2d103
Autor:
Yue Xu, Diane R Wagner, Elena Bekerman, Michael Chiou, Aaron W James, Dennis Carter, Michael T Longaker
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11279 (2010)
Cytoskeletal tension is an intracellular mechanism through which cells convert a mechanical signal into a biochemical response, including production of cytokines and activation of various signaling pathways.Adipose-derived stromal cells (ASCs) were a
Externí odkaz:
https://doaj.org/article/efff7334f7f94bd9bf4155623e02819e
Autor:
Aaron W James, Alexander A Theologis, Samantha A Brugmann, Yue Xu, Antoine L Carre, Philipp Leucht, Katherine Hamilton, Kenneth S Korach, Michael T Longaker
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7120 (2009)
While premature suture fusion, or craniosynostosis, is a relatively common condition, the cause is often unknown. Estrogens are associated with growth plate fusion of endochondral bones. In the following study, we explore the previously unknown signi
Externí odkaz:
https://doaj.org/article/ee7e9dd23dc649b0b24489e0e6042a0d