Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Aaron T. Wright"'
Autor:
Maria Font-Farre, Daniel Brown, Reka Toth, Chidambareswaren Mahadevan, Melissa Brazier-Hicks, Kyoko Morimoto, Farnusch Kaschani, John Sinclair, Richard Dale, Samantha Hall, Melloney Morris, Markus Kaiser, Aaron T. Wright, Jonathan Burton, Renier A. L. van der Hoorn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Eukaryotes produce a large number of cytochrome P450s that mediate the synthesis and degradation of diverse endogenous and exogenous metabolites. Yet, most of these P450s are uncharacterized and global tools to study these challenging, membr
Externí odkaz:
https://doaj.org/article/7d62dcaa4bcb49e79c3ba9092591fd25
Autor:
Lindsey M. Pieper, Peter Spanogiannopoulos, Regan F. Volk, Carson J. Miller, Aaron T. Wright, Peter J. Turnbaugh
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The microbiome is an underappreciated contributor to intestinal drug metabolism with broad implications for drug efficacy and toxicity. While considerable progress has been made toward identifying the gut bacterial genes and enzymes involved
Externí odkaz:
https://doaj.org/article/f83c7a0eeaf4426f93a48cd22b21ff80
Autor:
Bryan J. Killinger, Christopher Whidbey, Natalie C. Sadler, Adrian J. DeLeon, Nathalie Munoz, Young-Mo Kim, Aaron T. Wright
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract While deprivation of dietary fiber has been associated with adverse health outcomes, investigations concerning the effect of dietary fiber on the gut microbiome have been largely limited to compositional sequence-based analyses or utilize a
Externí odkaz:
https://doaj.org/article/bc65aa0687a3432ca6dad29598eb4b9e
Autor:
Elias K. Zegeye, Colin J. Brislawn, Yuliya Farris, Sarah J. Fansler, Kirsten S. Hofmockel, Janet K. Jansson, Aaron T. Wright, Emily B. Graham, Dan Naylor, Ryan S. McClure, Hans C. Bernstein
Publikováno v:
mSystems, Vol 4, Iss 4 (2019)
ABSTRACT Soil microorganisms play fundamental roles in cycling of soil carbon, nitrogen, and other nutrients, yet we have a poor understanding of how soil microbiomes are shaped by their nutritional and physical environment. In this study, we investi
Externí odkaz:
https://doaj.org/article/1baa4b3c42bf4c0e87e37baef2c56bb5
Autor:
Mary S Dickinson, Lindsey N Anderson, Bobbie-Jo M Webb-Robertson, Joshua R Hansen, Richard D Smith, Aaron T Wright, Kevin Hybiske
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007698 (2019)
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infection, responsible for millions of infections each year. Despite this high prevalence, the elucidation of the molecular mechanisms of Chlamydia pathogenesis has been
Externí odkaz:
https://doaj.org/article/d80c2cfcc3d64ba490ed5b51081ae4ee
Autor:
Whitney L. Garcia, Carson J. Miller, Gerard X. Lomas, Kari A. Gaither, Kimberly J. Tyrrell, Jordan N. Smith, Kristoffer R. Brandvold, Aaron T. Wright
Publikováno v:
Chemical Research in Toxicology. 35:585-596
Publikováno v:
Israel Journal of Chemistry. 63
Autor:
Christine H Chang, William C Nelson, Abby Jerger, Aaron T Wright, Robert G Egbert, Jason E McDermott
Publikováno v:
Bioinformatics Advances. 3
Motivation The vast expansion of sequence data generated from single organisms and microbiomes has precipitated the need for faster and more sensitive methods to assess evolutionary and functional relationships between proteins. Representing proteins
Autor:
Lindsey M. Pieper, Peter Spanogiannopoulos, Regan F. Volk, Carson J. Miller, Aaron T. Wright, Peter J. Turnbaugh
The microbiome is an underappreciated contributor to intestinal drug metabolism with broad implications for drug efficacy and toxicity. While considerable progress has been made towards identifying the gut bacterial genes and enzymes involved, the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::534a3b5e31d0635b876ad861f30d43f4
https://doi.org/10.1101/2022.10.25.513779
https://doi.org/10.1101/2022.10.25.513779
Autor:
Sankarganesh Krishnamoorthy, Andrea K. Steiger, William C. Nelson, Robert G. Egbert, Aaron T. Wright
Publikováno v:
Chemical communications (Cambridge, England). 58(58)
Development of profiling strategies to provide high resolution understanding of enzymes involved in bacterial infections remains an important need. These strategies help resolve enzyme mechanisms of actions and can guide therapeutic development. We h