Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Aaron T. Garnett"'
Autor:
Joseph Azofeifa, Phillip A. Richmond, Qinghong Zhang, Xuedong Liu, Cathryn M Toomey, Graycen Wheeler, Robin D. Dowell, Eric Bunker, Samuel S Karman, Aaron T. Garnett, Gilson J Sanchez, Quanbin Xu
Publikováno v:
Nucleic Acids Research
Histone deacetylase inhibitors (HDACIs) are known to alter gene expression by both up- and down-regulation of protein-coding genes in normal and cancer cells. However, the exact regulatory mechanisms of action remain uncharacterized. Here we investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3631ba92418db660c194712e2008763b
https://doi.org/10.1093/nar/gkx1225
https://doi.org/10.1093/nar/gkx1225
Publikováno v:
genesis. 51:457-470
The appearance of novel anatomic structures during evolution is driven by changes to the networks of transcription factors, signaling pathways, and downstream effector genes controlling development. The nature of the changes to these developmental ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34472869cd586e5e368ea75d41b81a36
https://doi.org/10.1002/dvg.22403
https://doi.org/10.1002/dvg.22403
Publikováno v:
Development. 139:4220-4231
Neural crest cells generate a range of cells and tissues in the vertebrate head and trunk, including peripheral neurons, pigment cells, and cartilage. Neural crest cells arise from the edges of the nascent central nervous system, a domain called the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16e76e591c9d09e2f246fcf3d171060
https://doi.org/10.1242/dev.081497
https://doi.org/10.1242/dev.081497
Autor:
Aaron T. Garnett, Wei Li, Eric Van Otterloo, Robert A. Cornell, Maria V. Cattell, Daniel Meulemans Medeiros
Publikováno v:
Development. 139:720-730
Gene duplication has been proposed to drive the evolution of novel morphologies. After gene duplication, it is unclear whether changes in the resulting paralogs’ coding-regions, or in their cis-regulatory elements, contribute most significantly to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519d387e1ca8ddf9c95c0296cbaa967e
https://doi.org/10.1242/dev.071308
https://doi.org/10.1242/dev.071308
Publikováno v:
Evolution & Development. 14:104-115
SUMMARY Despite deep evolutionary roots in the metazoa, the gene regulatory network driving germ layer specification is surprisingly labile both between and within phyla. In Xenopus laevis, SoxB1- and SoxF-type transcription factors are intimately in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::130bfd4f30f8889a36aa5a763fe3f213
https://doi.org/10.1111/j.1525-142x.2011.00525.x
https://doi.org/10.1111/j.1525-142x.2011.00525.x
Autor:
Benjamin P. Lewis, Liana F. Lareau, Richard E. Green, Marco Blanchette, Aaron T. Garnett, R. Tyler Hillman, Donald C. Rio, Steven E. Brenner
Publikováno v:
ISMB (Supplement of Bioinformatics)
We have recently shown that a third of reliably-inferred alternative mRNA isoforms are candidates for nonsense-mediated mRNA decay (NMD), an mRNA surveillance system (Lewis et al., 2003; Proc. Natl Acad. Sci. USA, 100, 189–192). Rather than being t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f3fa0c0616522ac6f6d539c4ab6eca
https://doi.org/10.1093/bioinformatics/btg1015
https://doi.org/10.1093/bioinformatics/btg1015
Autor:
David Jandzik, Aaron T. Garnett, Daniel Meulemans Medeiros, Jr-Kai Yu, Tyler A. Square, Maria V. Cattell
Publikováno v:
Nature. 518(7540)
A tissue with many of the defining features of vertebrate cellular cartilage is shown to form transiently in larvae of the invertebrate chordate amphioxus, indicating that the origin of the vertebrate head skeleton depended not on evolution of a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad74c45ebe1f143a2d303c04aea83be
https://pubmed.ncbi.nlm.nih.gov/25487155
https://pubmed.ncbi.nlm.nih.gov/25487155
Publikováno v:
Genesis (New York, N.Y. : 2000). 51(7)
The appearance of novel anatomic structures during evolution is driven by changes to the networks of transcription factors, signaling pathways, and downstream effector genes controlling development. The nature of the changes to these developmental ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b775f619b07f1642e86a3cc86147c026
https://pubmed.ncbi.nlm.nih.gov/23712931
https://pubmed.ncbi.nlm.nih.gov/23712931
Autor:
Hyun-Jung Kim, Aaron T. Garnett, J. Gage Crump, Daniel Meulemans Medeiros, Woojin An, Samuel G. Cox
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 8, Iss 9, p e1002938 (2012)
PLoS Genetics, Vol 8, Iss 9, p e1002938 (2012)
The neural crest (NC) is a vertebrate-specific cell population that exhibits remarkable multipotency. Although derived from the neural plate border (NPB) ectoderm, cranial NC (CNC) cells contribute not only to the peripheral nervous system but also t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c97aa45ce32279e7cde514648815cc9
http://europepmc.org/articles/PMC3447937
http://europepmc.org/articles/PMC3447937
Autor:
Fiona C. Wardle, Michael B. Eisen, Sharon L. Amacher, Michael J. Gilchrist, Tina M. Han, Aaron T. Garnett, James C. Smith
Publikováno v:
Development (Cambridge, England). 136(5)
The zebrafish genes spadetail (spt) and no tail (ntl) encode T-box transcription factors that are important for early mesoderm development. Although much has been done to characterize these genes, the identity and location of target regulatory elemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e849cbcc18bf1d6939eba52eba60ee
https://pubmed.ncbi.nlm.nih.gov/19158186
https://pubmed.ncbi.nlm.nih.gov/19158186