Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Aaron T Blanchard"'
Autor:
T. Curtis Shoyer, Kasie L. Collins, Trevor R. Ham, Aaron T. Blanchard, Juilee N. Malavade, Benjamin A. Johns, Jennifer L. West, Brenton D. Hoffman
Publikováno v:
Cell Reports: Methods, Vol 4, Iss 7, Pp 100815- (2024)
Summary: The ability of cells to sense and respond to mechanical forces is critical in many physiological and pathological processes. However, determining the mechanisms by which forces affect protein function inside cells remains challenging. Motiva
Externí odkaz:
https://doaj.org/article/1d829633ca9349298a176df6ee0bbc11
Publikováno v:
The Journal of Physical Chemistry B. 126:7495-7509
Molecular motors, such as myosin and kinesin, perform diverse tasks ranging from vesical transport to bulk muscle contraction. Synthetic molecular motors may eventually be harnessed to perform similar tasks in versatile synthetic systems. The most pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b40cadacd9841d4cfdc59a374f2ef2
https://doi.org/10.1021/acs.jpcb.2c01897
https://doi.org/10.1021/acs.jpcb.2c01897
Autor:
Aaron T. Blanchard, Zi Li, Elizabeth C. Duran, Catherine E. Scull, J. Damon Hoff, Keenan R. Wright, Victor Pan, Nils G. Walter
Publikováno v:
Nano Lett
DNA-based FluoroCubes were recently developed as a solution to photobleaching, a ubiquitous limitation of fluorescence microscopy (Niekamp, Stuurman, & Vale, Nature Methods, 2020). FluoroCubes – compact ~4×4×5.4nm(3) four-helix bundles bound by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1ea601bdd4988a7bd4866ec0325667
https://europepmc.org/articles/PMC10080265/
https://europepmc.org/articles/PMC10080265/
Publikováno v:
ACS Appl Mater Interfaces
DNA-nanoparticle (NP) conjugates have been used to knockdown gene expression transiently and effectively, making them desirable tools for gene regulation therapy. Because DNA-NPs are constitutively active and are rapidly taken up by most cell types,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c7c98f81e8cc5ba247d66ca9ee6c1ad
https://doi.org/10.1021/acsami.0c07609
https://doi.org/10.1021/acsami.0c07609
Autor:
Sk Aysha Rashid, Aaron T. Blanchard, J. Dale Combs, Natasha Fernandez, Yixiao Dong, Hee Cheol Cho, Khalid Salaita
Publikováno v:
ACS nano. 16(4)
Cardiac muscle cells (CMCs) are the unit cells that comprise the heart. CMCs go through different stages of differentiation and maturation pathways to fully mature into beating cells. These cells can sense and respond to mechanical cues through recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429cc16a2ba711f67c26df8641266436
https://pubmed.ncbi.nlm.nih.gov/35324164
https://pubmed.ncbi.nlm.nih.gov/35324164
Autor:
Victor Pui-Yan Ma, Yuesong Hu, Anna V. Kellner, Joshua M. Brockman, Arventh Velusamy, Aaron T. Blanchard, Brian D. Evavold, Ronen Alon, Khalid Salaita
Publikováno v:
Science advances. 8(8)
T cells defend against cancer and viral infections by rapidly scanning the surface of target cells seeking specific peptide antigens. This key process in adaptive immunity is sparked upon T cell receptor (TCR) binding of antigens within cell-cell jun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385af07f41d1cac113074d21ff13e156
https://pubmed.ncbi.nlm.nih.gov/35213231
https://pubmed.ncbi.nlm.nih.gov/35213231
Autor:
Khalid Salaita, Jonathan P. K. Doye, Navoneel Sen, Yuxin Duan, Aaron T. Blanchard, Alisina Bazrafshan, Hanquan Su, Brooke Andrews, Hemani Chhabra, Travis A. Meyer, Joshua M. Brockman, R. Brian Dyer, Yonggang Ke
Publikováno v:
J Am Chem Soc
In single-molecule force spectroscopy (SMFS), a tethered molecule is stretched using a specialized instrument to study how macromolecules extend under force. One problem in SMFS is the serial and slow nature of the measurements, performed one molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6cc3981aeb851ef61b0e727ecf972f
https://ora.ox.ac.uk/objects/uuid:560ccf85-ddf7-418c-8d8f-25484a2e4635
https://ora.ox.ac.uk/objects/uuid:560ccf85-ddf7-418c-8d8f-25484a2e4635
Autor:
Wenchun Chen, Alisina Bazrafshan, Anna V. Kellner, Rachel L. Bender, Khalid Salaita, Roxanne Glazier, Joshua M. Brockman, J. Dale Combs, Hanquan Su, Aaron T. Blanchard, M. Edward Quach, Alexa L. Mattheyses, Renhao Li
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Many cellular processes, including cell division, development, and cell migration require spatially and temporally coordinated forces transduced by cell-surface receptors. Nucleic acid-based molecular tension probes allow one to visualize the piconew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae3af7b03fad75251e8d1f76871a399
https://doi.org/10.1038/s41467-021-24602-x
https://doi.org/10.1038/s41467-021-24602-x