Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aaron Snoberger"'
Autor:
Aaron Snoberger, Bipasha Barua, Jennifer L Atherton, Henry Shuman, Eva Forgacs, Yale E Goldman, Donald A Winkelmann, E Michael Ostap
Publikováno v:
eLife, Vol 10 (2021)
Hypertrophic cardiomyopathies (HCMs) are the leading cause of acute cardiac failure in young individuals. Over 300 mutations throughout β-cardiac myosin, including in the motor domain, are associated with HCM. A β-cardiac myosin motor mutation (R71
Externí odkaz:
https://doaj.org/article/a7523ab1d3fc41fc9e768c62b8590538
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Proteasomal ATPases contain functionally important coiled-coil (CC) domains, the mechanistic role of which is not fully understood. Here, the authors provide evidence for three distinct CC conformations, showing that CC conformational changes enable
Externí odkaz:
https://doaj.org/article/d753a210f94644cf8f78d72fae386d53
Autor:
Ross TA Pedersen, Aaron Snoberger, Serapion Pyrpassopoulos, Daniel Safer, David G Drubin, E Michael Ostap
SummaryPedersen, Snoberger et al. measure the force-sensitivity of the yeast endocytic the myosin-1 called Myo5 and find that it is more likely to generate power than to serve as a force-sensitive anchor in cells. Implications for Myo5’s role in cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb196c116c5dc09df583b0f44d9e328d
https://doi.org/10.1101/2023.03.21.533689
https://doi.org/10.1101/2023.03.21.533689
Autor:
Aaron Snoberger, Yale E. Goldman, Eva Forgacs, Henry Shuman, E. Michael Ostap, Bipasha Barua, Jennifer L. Atherton, Donald A. Winkelmann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46ec188b006e3329b1e7b86aabad699f
https://doi.org/10.7554/elife.63691.sa2
https://doi.org/10.7554/elife.63691.sa2
Autor:
E. Michael Ostap, Aaron Snoberger, Eva Forgacs, Donald A. Winkelmann, Henry Shuman, Bipasha Barua, Yale E. Goldman, Jennifer L. Atherton
Hypertrophic cardiomyopathies (HCMs) are the leading cause of acute cardiac failure in young individuals. Over 300 mutations throughout β-cardiac myosin, including in the motor domain, are associated with HCM. A β-cardiac myosin motor mutation (R71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d76fa6fc6ee63399d57cd7e26d13486b
https://doi.org/10.1101/2020.10.02.323782
https://doi.org/10.1101/2020.10.02.323782
Autor:
Aaron Snoberger, Eva Forgacs, Jennifer L. Atherton, Donald A. Winkelmann, Bipasha Barua, E. Michael Ostap, Henry Shuman, Yale E. Goldman
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Hypertrophic cardiomyopathies (HCMs) are the leading cause of acute cardiac failure in young individuals. Over 300 mutations throughout β-cardiac myosin, including in the motor domain, are associated with HCM. A β-cardiac myosin motor mutation (R71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d3f7a7f40e22f9890f6339fa9fa08b
https://pubmed.ncbi.nlm.nih.gov/33605878
https://pubmed.ncbi.nlm.nih.gov/33605878
Publikováno v:
Biophysical Journal. 118:436a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0f4dc6dc187e7a8e2bfb2ec28aa0864
https://doi.org/10.1016/j.bpj.2019.11.2445
https://doi.org/10.1016/j.bpj.2019.11.2445
Autor:
Donald A. Winkelmann, Yale E. Goldman, Aaron Snoberger, Eva Forgacs, Jennifer L. Atherton, Bipasha Barua, E. Michael Ostap
Publikováno v:
Biophysical Journal. 118:177a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f78a61454a0b7fca8e0b54e38d9d01a
https://doi.org/10.1016/j.bpj.2019.11.1082
https://doi.org/10.1016/j.bpj.2019.11.1082
Autor:
Aaron Snoberger, David M. Smith
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::505f65b15c87b149749c0f912f178479
https://doi.org/10.1096/fasebj.2018.32.1_supplement.526.42
https://doi.org/10.1096/fasebj.2018.32.1_supplement.526.42
Publikováno v:
Nature Communications
The primary functions of the proteasome are driven by a highly allosteric ATPase complex. ATP binding to only two subunits in this hexameric complex triggers substrate binding, ATPase–20S association and 20S gate opening. However, it is unclear how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3423c6cf692e1e9e48351a109da35c8
https://doi.org/10.1038/ncomms9520
https://doi.org/10.1038/ncomms9520