Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Aaron Simoni"'
Autor:
Laura Schwartz, Kristin Salamon, Aaron Simoni, Tad Eichler, Ashley R. Jackson, Matthew Murtha, Brian Becknell, Andrew Kauffman, Sarah Linn-Peirano, Natalie Holdsworth, Vidhi Tyagi, Hancong Tang, Steve Rust, Hanna Cortado, Irina Zabbarova, Anthony Kanai, John David Spencer
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114007- (2024)
Summary: Urinary tract infections (UTIs) commonly afflict people with diabetes. To better understand the mechanisms that predispose diabetics to UTIs, we employ diabetic mouse models and altered insulin signaling to show that insulin receptor (IR) sh
Externí odkaz:
https://doaj.org/article/26705d777a114915af5c25ba310213b6
Autor:
Adam J. Rauckhorst, Gabriela Vasquez Martinez, Gabriel Mayoral Andrade, Hsiang Wen, Ji Young Kim, Aaron Simoni, Claudia Robles-Planells, Kranti A. Mapuskar, Prerna Rastogi, Emily J. Steinbach, Michael L. McCormick, Bryan G. Allen, Navjot S. Pabla, Ashley R. Jackson, Mitchell C. Coleman, Douglas R. Spitz, Eric B. Taylor, Diana Zepeda-Orozco
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101849- (2024)
Objective: Energy-intensive kidney reabsorption processes essential for normal whole-body function are maintained by tubular epithelial cell metabolism. Although tubular metabolism changes markedly following acute kidney injury (AKI), it remains uncl
Externí odkaz:
https://doaj.org/article/3fd3e25948fb47dd89066773a4e94c07
Autor:
Adam J. Rauckhorst, Gabriela Vasquez Martinez, Gabriel Mayoral Andrade, Hsiang Wen, Ji Young Kim, Aaron Simoni, Kranti A. Mapuskar, Prerna Rastogi, Emily J Steinbach, Michael L. McCormick, Bryan G. Allen, Navjot S. Pabla, Ashley R. Jackson, Mitchell C. Coleman, Douglas R. Spitz, Eric B. Taylor, Diana Zepeda-Orozco
Publikováno v:
bioRxiv
Energy-intensive kidney reabsorption processes essential for normal whole-body function are maintained by tubular epithelial cell metabolism. Tubular metabolism changes markedly following acute kidney injury (AKI), but which changes are adaptive vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbb483ddda5a42912878ea4efd93997
https://doi.org/10.1101/2023.01.31.526492
https://doi.org/10.1101/2023.01.31.526492
Autor:
Laura Schwartz, M. Skye Bochter, Aaron Simoni, Kristin Bender, Juan de Dios Ruiz Rosado, Israel Cotzomi-Ortega, Yuriko I. Sanchez-Zamora, Brian Becknell, Sarah Linn, Birong Li, Nicholas Santoro, Tad Eichler, John David Spencer
Publikováno v:
Proceedings of the National Academy of Sciences. 120
With the emergence of antibiotic-resistant bacteria, innovative approaches are needed for the treatment of urinary tract infections. Boosting antimicrobial peptide expression may provide an alternative to antibiotics. Here, we developed reporter cell
Autor:
Keith R. Pierce, Steven Creacy, Tad Eichler, Andrew L. Schwaderer, David S. Hains, Claudia Mosquera Vasquez, John David Spencer, Aaron Simoni
Publikováno v:
J Clin Invest
Ribonuclease 7 (RNase 7) is an antimicrobial peptide that prevents urinary tract infections (UTI); however, it is yet unknown how RNASE7 genetic variations affect its antimicrobial activity and its mitigation of UTI risk. This study determined whethe