Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aaron Sather"'
A novel, convergent synthesis of aminotriazoloquinazolines is reported. These heterocycles are reliably prepared via a “click” reaction between readily available aryl carbodiimides and acyl hydrazides. Such products are of particular interest wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe9d6fe0e6a82a3b66f50933ac628a6e
https://doi.org/10.26434/chemrxiv-2022-vh7m3
https://doi.org/10.26434/chemrxiv-2022-vh7m3
Autor:
Matthew A. Larsen, Josep Saurí, Elisabeth Hennessy, Aaron Sather, Yu-hong Lam, Madeleine C. Deem
Publikováno v:
Journal of the American Chemical Society. 142:726-732
A new general de novo synthesis of pharmaceutically important N-(hetero)aryl piperidines is reported. This protocol uses a robustly diastereoselective reductive amination/aza-Michael reaction sequence to achieve rapid construction of complex polysubs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d37d6c1c1977b2e93cd09cfc2cb543
https://doi.org/10.1021/jacs.9b13114
https://doi.org/10.1021/jacs.9b13114
Autor:
Aaron Sather, Theodore A. Martinot
Publikováno v:
Organic Process Research & Development. 23:1725-1739
To circumvent a current limitation in palladium-catalyzed C–N cross-coupling methodology, high-throughput experimentation was used to identify a catalyst capable of fusing piperidine-based nucleoph...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a581c2baee2612687f551c1284123c65
https://doi.org/10.1021/acs.oprd.9b00233
https://doi.org/10.1021/acs.oprd.9b00233
Autor:
Josep Saurí, Aaron Sather, Elisabeth Hennessy, Madeleine C. Deem, Yu-hong Lam, Matthew A. Larsen
A new general de novo synthesis of pharmaceutically important N-(hetero)aryl piperidines is reported. This protocol uses a robustly diastereoselective reductive amination/aza-Michael reaction sequence to achieve rapid construction of complex polysubs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154c1adb3fb8addedf3d277334bd02ab
https://doi.org/10.26434/chemrxiv.11317901.v1
https://doi.org/10.26434/chemrxiv.11317901.v1