Zobrazeno 1 - 10
of 572
pro vyhledávání: '"Aaron S. Dumont"'
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-33 (2024)
Abstract Drug delivery systems (DDS) have recently emerged as a promising approach for the unique advantages of drug protection and targeted delivery. However, the access of nanoparticles/drugs to the central nervous system (CNS) remains a challenge
Externí odkaz:
https://doaj.org/article/e4dd5b88d2174408981517c661dabc94
Autor:
Alejandra N. Martinez, Giovane G. Tortelote, Crissey L. Pascale, Uduak-Obong I. Ekanem, Ana Paula de O. Leite, Isabella G. McCormack, Aaron S. Dumont
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 773 (2024)
Cerebral aneurysms (CA) are a type of vascular disease that causes significant morbidity and mortality with rupture. Dysfunction of the vascular smooth muscle cells (VSMCs) from circle of Willis (CoW) vessels mediates CA formation, as they are the ma
Externí odkaz:
https://doaj.org/article/e739bd50f17847ee904c1a487f2a06f2
Autor:
Yinghua Jiang, Jinrui Han, Pierce Spencer, Yadan Li, Samuel J. Vodovoz, Ming-Ming Ning, Ning Liu, Xiaoying Wang, Aaron S. Dumont
Publikováno v:
Brain Hemorrhages, Vol 2, Iss 3, Pp 116-123 (2021)
Intravenous tissue type plasminogen activator thrombolytic therapy has long been a mainstay in acute ischemic stroke therapy. However, patients receiving IV tPA therapy may have variable response with some subsets of patients having worsened outcomes
Externí odkaz:
https://doaj.org/article/e3a16ba095dc4754ae4514af9b6925e7
Autor:
Ning Liu, Jinrui Han, Yadan Li, Yinghua Jiang, Samuel X. Shi, Josephine Lok, Michael Whalen, Aaron S. Dumont, Xiaoying Wang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background Traumatic brain injury (TBI) is a significant cause of death and disability worldwide. The TLR4-NFκB signaling cascade is the critical pro-inflammatory activation pathway of leukocytes after TBI, and modulating this signaling cas
Externí odkaz:
https://doaj.org/article/922b7f40a5f2438fa7c9c792a4b53768
Publikováno v:
Interdisciplinary Neurosurgery, Vol 29, Iss , Pp 101545- (2022)
Objective: The objective of this study is to identify the top 100 social media influencers in Neurosurgery on Twitter, describe who they are, and correlate their social media influence with their academic influence. Methods: Twitter influence scores
Externí odkaz:
https://doaj.org/article/db885133e4a240e68c5a3f3a77c74b10
Publikováno v:
Brain Hemorrhages, Vol 2, Iss 1, Pp 1-5 (2021)
Experimental animal models are most valuable to study the initiation and growth of cerebral aneurysms. The aim of our study is to analyze the time course, incidence, location and growth pattern of intracranial aneurysms in an experimental rat model.
Externí odkaz:
https://doaj.org/article/f2c98273fcbd48509374ca421ccf486c
Publikováno v:
Interdisciplinary Neurosurgery, Vol 27, Iss , Pp 101412- (2022)
We present the case of a 78-year-old patient with a large right internal carotid artery aneurysm found incidentally after 2-weeks of blurry vision without headache. The patient underwent endovascular coiling of the aneurysm with flow diverting stent
Externí odkaz:
https://doaj.org/article/2fd6972dcc544c44801cfdd33f1b4754
Autor:
William S. Dodd, Dimitri Laurent, Aaron S. Dumont, David M. Hasan, Pascal M. Jabbour, Robert M. Starke, Koji Hosaka, Adam J. Polifka, Brian L. Hoh, Nohra Chalouhi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 15 (2021)
Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many years of investigation and clinical trials. Modern advances in basic scie
Externí odkaz:
https://doaj.org/article/10f3a1a3dc2243049e0a22c160cb2a0d
Autor:
Chongjie Cheng, Xiaoshu Wang, Yinghua Jiang, Yadan Li, Zhengbu Liao, Wenlu Li, Zhanyang Yu, Michael J. Whalen, Josephine Lok, Aaron S. Dumont, Ning Liu, Xiaoying Wang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Microvascular failure is one of the key pathogenic factors in the dynamic pathological evolution after traumatic brain injury (TBI). Our laboratory and others previously reported that Annexin A2 functions in blood-brain barrier (BBB) development and
Externí odkaz:
https://doaj.org/article/5eb0d87c27504fd2bd52c4b89f5831f6
Autor:
Samuel X. Shi, Samuel J. Vodovoz, Yuwen Xiu, Ning Liu, Yinghua Jiang, Prasad V. G. Katakam, Gregory Bix, Aaron S. Dumont, Xiaoying Wang
Publikováno v:
Cells, Vol 11, Iss 13, p 2011 (2022)
In the pathophysiology of hemorrhagic stroke, the perturbation of the neurovascular unit (NVU), a functional group of the microvascular and brain intrinsic cellular components, is implicated in the progression of secondary injury and partially inform
Externí odkaz:
https://doaj.org/article/eb7e2f0c69244715b73d23b1e178f6af