Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Aaron R. Victor"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
As first responder cells in host defense, neutrophils must be carefully regulated to prevent collateral tissue injury. However, the intracellular events that titrate the neutrophil’s response to inflammatory stimuli remain poorly understood. As a m
Externí odkaz:
https://doaj.org/article/29e2351d1dbd455bb86491525b0b81be
Autor:
Zhenzi Peng, Cuiwei Liu, Aaron R. Victor, Duo-Yao Cao, Luciana C. Veiras, Ellen A. Bernstein, Zakir Khan, Jorge F. Giani, Xiaojiang Cui, Kenneth E. Bernstein, Derick Okwan-Duodu
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Granulocytes are key players in cancer metastasis. While tumor-induced de novo expansion of immunosuppressive myeloid-derived suppressor cells (MDSCs) is well-described, the fate and contribution of terminally differentiated mature neutrophils to the
Externí odkaz:
https://doaj.org/article/172498add4db402ab102601c328e4a79
Autor:
DuoYao Cao, Zakir Khan, Xiaomo Li, Suguru Saito, Ellen A Bernstein, Aaron R Victor, Faizan Ahmed, Aoi O Hoshi, Luciana C Veiras, Tomohiro Shibata, Mingtian Che, Lei Cai, Ryan E Temel, Jorge F Giani, Daniel J Luthringer, Ajit S Divakaruni, Derick Okwan-Duodu, Kenneth E Bernstein
Publikováno v:
Cardiovascular Research.
Aims The metabolic failure of macrophages to adequately process lipid is central to the etiology of atherosclerosis. Here, we examine the role of macrophage angiotensin converting enzyme (ACE) in a mouse model of PCSK9 induced atherosclerosis. Method
Autor:
Alyson R. Yeckes, Aaron R. Victor, Zheng Zhu, Meena Narayanan, Bharani Srinivasan, Bethany Bruce, Jonathan Kaye
Publikováno v:
The Journal of Immunology.
Here we report that the murine Tox gene encodes two proteins from a single mRNA, and we investigate the mechanism of production and function of these proteoforms. The annotated thymocyte selection–associated HMG-box protein (TOX) coding sequence is
Publikováno v:
Cytojournal. 20:11
Objectives: Lymphoid cell rich fine-needle aspirations (FNAs) of the salivary glands pose a diagnostic dilemma, with a wide range of differential diagnoses that include several benign and malignant entities. There is limited literature regarding the
Autor:
Jorge F. Giani, Kenneth E. Bernstein, Luciana C Veiras, Ellen A. Bernstein, Cuiwei Liu, Derick Okwan-Duodu, Aaron R. Victor, Duo-Yao Cao, Xiaojiang Cui, Zhenzi Peng, Zakir Khan
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
Granulocytes are key players in cancer metastasis. While tumor-induced de novo expansion of immunosuppressive myeloid-derived suppressor cells (MDSCs) is well-described, the fate and contribution of terminally differentiated mature neutrophils to the
Autor:
Jason R. Pitarresi, Wenjuan Dong, Wing Keung Chan, Jianying Zhang, Sarah Manz, Edward L. Briercheck, Michael C. Ostrowski, Youssef Youssef, Raleigh D. Kladney, Steven D. Scoville, Michael A. Caligiuri, Ansel P. Nalin, Tiffany Hughes, Lai-Chu Wu, Min Wei, Gustavo Leone, Charlene Mao, Jianhua Yu, Aharon G. Freud, Susan McClory, Charlie Chen, Aaron R. Victor
Publikováno v:
The Journal of Immunology. 199:2333-2342
Group 3 innate lymphoid cells (ILC3s) are important regulators of the immune system, maintaining homeostasis in the presence of commensal bacteria, but activating immune defenses in response to microbial pathogens. ILC3s are a robust source of IL-22,
Autor:
Kelsey Chatman, Wing Keung Chan, Christopher C. Oakes, Karen A. Young, Jianying Zhang, Charlene Mao, Aharon G. Freud, Steven D. Scoville, Jianhua Yu, Christoph Weigel, Aaron R. Victor, Michael A. Caligiuri, Mary M. Nemer
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 200(2)
The surface receptor FcγRIIIA (CD16a) is encoded by the FCGR3A gene and is acquired by human NK cells during maturation. NK cells bind the Fc portion of IgG via CD16a and execute Ab-dependent cell-mediated cytotoxicity, which is critical for the eff
Autor:
Jianying Zhang, Jianhua Yu, Ichiro Nakano, Xiaoming He, Sung Hak Kim, Jianhong Chu, Justus B. Cohen, Joseph C. Glorioso, Balveen Kaur, Aaron R. Victor, Paola Grandi, Youwei Wang, E. Antonio Chiocca, Wing Keung Chan, Michael A. Caligiuri, Jianfeng Han, Qi-En Wang, Walter Hans Meisen
Publikováno v:
Scientific Reports
Glioblastoma (GB) remains the most aggressive primary brain malignancy. Adoptive transfer of chimeric antigen receptor (CAR)-modified immune cells has emerged as a promising anti-cancer approach, yet the potential utility of CAR-engineered natural ki