Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Aaron R. Goldman"'
Autor:
Shalini Singh, Leila B. Giron, Maliha W. Shaikh, Shivanjali Shankaran, Phillip A. Engen, Zlata R. Bogin, Simona A. Bambi, Aaron R. Goldman, Joao L. L. C. Azevedo, Lorena Orgaz, Nuria de Pedro, Patricia González, Martin Giera, Aswin Verhoeven, Elena Sánchez-López, Ivona Pandrea, Toshitha Kannan, Ceylan E. Tanes, Kyle Bittinger, Alan L. Landay, Michael J. Corley, Ali Keshavarzian, Mohamed Abdel-Mohsen
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Background People living with HIV (PLWH), even when viral replication is controlled through antiretroviral therapy (ART), experience persistent inflammation. This inflammation is partly attributed to intestinal microbial dysbiosis and transl
Externí odkaz:
https://doaj.org/article/03326450ced04999be69828f4f9541f9
Autor:
Amin Izadpanah, Joseph C. Mudd, Joe G. N. Garcia, Sudesh Srivastav, Mohamed Abdel-Mohsen, Clovis Palmer, Aaron R. Goldman, Jay K. Kolls, Xuebin Qin, Jay Rappaport
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSevere COVID-19 results initially in pulmonary infection and inflammation. Symptoms can persist beyond the period of acute infection, and patients with Post-Acute Sequelae of COVID (PASC) often exhibit a variety of symptoms weeks or month
Externí odkaz:
https://doaj.org/article/e6397cf7b85b4dc0bf1a3ddf781f1494
Autor:
Monika Bhardwaj, Jennifer J. Lee, Amanda M. Versace, Sandra L. Harper, Aaron R. Goldman, Mary Ann S. Crissey, Vaibhav Jain, Mahendra Pal Singh, Megane Vernon, Andrew E. Aplin, Seokwoo Lee, Masao Morita, Jeffrey D. Winkler, Qin Liu, David W. Speicher, Ravi K. Amaravadi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
Lysosomal inhibition elicited by palmitoyl-protein thioesterase 1 (PPT1) inhibitors such as DC661 can produce cell death, but the mechanism for this is not completely understood. Programmed cell death pathways (autophagy, apoptosis, necroptosis, ferr
Externí odkaz:
https://doaj.org/article/fad0eadd0ff64a57986f4c0b83cbe4f7
Autor:
Leila B. Giron, Michael J. Peluso, Jianyi Ding, Grace Kenny, Netanel F. Zilberstein, Jane Koshy, Kai Ying Hong, Heather Rasmussen, Gregory E. Miller, Faraz Bishehsari, Robert A. Balk, James N. Moy, Rebecca Hoh, Scott Lu, Aaron R. Goldman, Hsin-Yao Tang, Brandon C. Yee, Ahmed Chenna, John W. Winslow, Christos J. Petropoulos, J. Daniel Kelly, Haimanot Wasse, Jeffrey N. Martin, Qin Liu, Ali Keshavarzian, Alan Landay, Steven G. Deeks, Timothy J. Henrich, Mohamed Abdel-Mohsen
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Externí odkaz:
https://doaj.org/article/6e5e56aca1ba4618a1ad54b38b692378
Autor:
Leila B. Giron, Clovis S. Palmer, Qin Liu, Xiangfan Yin, Emmanouil Papasavvas, Radwa Sharaf, Behzad Etemad, Mohammad Damra, Aaron R. Goldman, Hsin-Yao Tang, Rowena Johnston, Karam Mounzer, Jay R. Kostman, Pablo Tebas, Alan Landay, Luis J. Montaner, Jeffrey M. Jacobson, Jonathan Z. Li, Mohamed Abdel-Mohsen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Current HIV cure-focused clinical trials rely on analytic treatment interruption (ATI) to evaluate post-treatment control (PTC). Here, combining untargetted metabolomics and glycomics in two HIV clinical cohorts, in vitro assays, and machine learning
Externí odkaz:
https://doaj.org/article/8389144aeb1a4d6d950f9fd144f01fe1
Autor:
Leila B. Giron, Harsh Dweep, Xiangfan Yin, Han Wang, Mohammad Damra, Aaron R. Goldman, Nicole Gorman, Clovis S. Palmer, Hsin-Yao Tang, Maliha W. Shaikh, Christopher B. Forsyth, Robert A. Balk, Netanel F. Zilberstein, Qin Liu, Andrew Kossenkov, Ali Keshavarzian, Alan Landay, Mohamed Abdel-Mohsen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/9d43aa506dba4c96a60a71df485dd3a5
Autor:
Leila B. Giron, Harsh Dweep, Xiangfan Yin, Han Wang, Mohammad Damra, Aaron R. Goldman, Nicole Gorman, Clovis S. Palmer, Hsin-Yao Tang, Maliha W. Shaikh, Christopher B. Forsyth, Robert A. Balk, Netanel F. Zilberstein, Qin Liu, Andrew Kossenkov, Ali Keshavarzian, Alan Landay, Mohamed Abdel-Mohsen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A disruption of the crosstalk between the gut and the lung has been implicated as a driver of severity during respiratory-related diseases. Lung injury causes systemic inflammation, which disrupts gut barrier integrity, increasing the permeability to
Externí odkaz:
https://doaj.org/article/106b035c6b02411ea9bcfd98efbe5a57
Autor:
Leila B. Giron, Emmanouil Papasavvas, Xiangfan Yin, Aaron R. Goldman, Hsin-Yao Tang, Clovis S. Palmer, Alan L. Landay, Jonathan Z. Li, John R. Koethe, Karam Mounzer, Jay R. Kostman, Qin Liu, Luis J. Montaner, Mohamed Abdel-Mohsen
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The likelihood of HIV rebound after stopping antiretroviral therapy (ART) is a combination of the size of HIV reservoirs that persist despite ART and the host immunological and inflammatory factors that control these reservoirs. Therefore, there is a
Externí odkaz:
https://doaj.org/article/0fa9e9d892ae46d3801779a44629a2bb
Autor:
Vaibhav Jain, Sandra L. Harper, Amanda M. Versace, Dylan Fingerman, Gregory Schuyler Brown, Monika Bhardwaj, Mary Ann S. Crissey, Aaron R. Goldman, Gordon Ruthel, Qin Liu, Aleksandra Zivkovic, Holgar Stark, Meenhard Herlyn, Phyllis A. Gimotty, David W. Speicher, Ravi K. Amaravadi
Publikováno v:
Cancer Discovery. 13:454-473
Lysosomal autophagy inhibition (LAI) with hydroxychloroquine or DC661 can enhance cancer therapy, but tumor regrowth is common. To elucidate LAI resistance, proteomics and immunoblotting demonstrated that LAI induced lipid metabolism enzymes in multi
Autor:
Rugang Zhang, Jianhuang Lin, Meenhard Herlyn, Wei Zhou, Heng Liu, Andrew V Kossenkov, Hsin-Yao Tang, Aaron R Goldman, Simona Lombardi
SCD1 inhibition suppresses CARM1-expressing ovarian cancer in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c15fa2457cf9a6fd0ec7454962e01f
https://doi.org/10.1158/2767-9764.23269422
https://doi.org/10.1158/2767-9764.23269422