Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Aaron R. Alizadeh"'
Autor:
Lowell L. Hart, Lynn E. Spitler, April K.S. Salama, Omid Hamid, Neal Evan Rothschild, Yi He, Christopher D. Turner, Joshua Zhang, Jose Lutzky, Anna C. Pavlick, Jason J. Luke, Douglas B. Johnson, Patrick A. Ott, Jeffrey R. Infante, C. Lance Cowey, Rebecca G. Bagley, Aaron R. Alizadeh, Thomas Hawthorne
Publikováno v:
Cancer. 125(7)
Background Glembatumumab vedotin is an antibody-drug conjugate that produced preliminary clinical activity against advanced melanoma in a phase 1 dose-escalation trial. The objective of the current study was to investigate further the antitumor activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7f2e6f860a722e822a5755184715bd
https://pubmed.ncbi.nlm.nih.gov/30690710
https://pubmed.ncbi.nlm.nih.gov/30690710
Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa
Autor:
Christopher E. Nichols, James P. Snyder, Jan Pohl, Aiming Sun, Mamoru Shoji, Walter Kisiel, Yang J. Lu, Hyunsuk Shim, Bernard E. McCarey, Dennis C. Liotta, Aaron R. Alizadeh, Ernest T. Parker, Cara Mosley
Publikováno v:
Journal of Drug Targeting. 16:185-197
Tissue factor (TF) is aberrantly expressed on tumor vascular endothelial cells (VECs) and on cancer cells in many malignant tumors, but not on normal VECs, making it a promising target for cancer therapy. As a transmembrane receptor for coagulation f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::becacc13022ac2ff00bbcc866d08b183
https://doi.org/10.1080/10611860801890093
https://doi.org/10.1080/10611860801890093
Autor:
Aaron R. Alizadeh, Jose Lutzky, Douglas B. Johnson, Lynn E. Spitler, April K.S. Salama, Patrick A. Ott, Omid Hamid, Neal Evan Rothschild, Jeffrey R. Infante, Ying Wang, Charles Lance Cowey, Rebecca G. Bagley, Lowell L. Hart, Xiaoyan Yin, Anna C. Pavlick, Jason J. Luke
Publikováno v:
Journal of Clinical Oncology. 35:109-109
109 Background: gpNMB is an internalizable transmembrane glycoprotein expressed in melanoma and multiple other tumor types. The ADC GV (CDX-011) delivers the potent cytotoxin MMAE to gpNMB+ cells. GV has shown promising activity in advanced melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f3e059535c7cbbe0608c1bd2f4a851
https://doi.org/10.1200/jco.2017.35.15_suppl.109
https://doi.org/10.1200/jco.2017.35.15_suppl.109
Autor:
Lowell L. Hart, Lynn E. Spitler, J. Zhang, Jose Lutzky, April K.S. Salama, Douglas B. Johnson, Patrick A. Ott, Charles Lance Cowey, Omid Hamid, Aaron R. Alizadeh, J. R. Infante, Neal Evan Rothschild, Anna C. Pavlick, Jason J. Luke, Rebecca G. Bagley, Y. He
Publikováno v:
Annals of Oncology. 27:vi393
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1eba33501baf30f86663a4b85a00d59
https://doi.org/10.1093/annonc/mdw379.42
https://doi.org/10.1093/annonc/mdw379.42