Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Aaron P. Roznowski"'
Publikováno v:
Viruses, Vol 12, Iss 6, p 670 (2020)
Bacteriophage ϕX174 uses a decamer of DNA piloting proteins to penetrate its host. These proteins oligomerize into a cell wall-spanning tube, wide enough for genome passage. While the inner surface of the tube is primarily lined with inward-facing a
Externí odkaz:
https://doaj.org/article/0b5f483e90cc452e90d60dc1b08aa111
Publikováno v:
J Virol
Most icosahedral viruses condense their genomes into volumetrically constrained capsids. However, concurrent genome biosynthesis and packaging are specific to single-stranded DNA (ssDNA) viruses. ssDNA genome packaging combines elements found in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ba6eeb7eb50dd8c954f81409238921
https://europepmc.org/articles/PMC8387035/
https://europepmc.org/articles/PMC8387035/
Publikováno v:
J Virol
In microviruses, 60 copies of the positively charged DNA binding protein J guide the single-stranded DNA genome into the icosahedral capsid. Consequently, ∼12% of the genome is icosahedrally ordered within virions. Although the internal volume of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fad31b676204ffbfa4e67868bb87fe
https://europepmc.org/articles/PMC6955274/
https://europepmc.org/articles/PMC6955274/
Autor:
Meixiao Wang, Anne McGill, April D. Burch, Martine Lavelle, Robert J. Young, Avenetti A. Andromita, Aaron P. Roznowski, Bentley A. Fane, Margaret H. Wilch, Vanessa A. Guzman, Anastasia Romanova, Ava Block, Samuel D. Love, Aimi Sekiguchi
Publikováno v:
Journal of Virology. 93
Although microviruses do not possess a visible tail structure, one vertex rearranges after interacting with host lipopolysaccharides. Most examinations of host range, eclipse, and penetration were conducted before this “host-induced” unique verte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c289bceddef55cb4bdfe0021f8883ce1
https://doi.org/10.1128/jvi.01767-18
https://doi.org/10.1128/jvi.01767-18
Autor:
April D. Burch, Margaret Hardy, Alexis R. Perez, Shuaizhi Li, Brody J. Blackburn, Curtis Johnson, Aaron P. Roznowski, Rodrigo H. Villarreal, Edward C. Tuckerman, Bentley A. Fane
Publikováno v:
Journal of Virology. 91
Two scaffolding proteins orchestrate ϕX174 morphogenesis. The internal scaffolding protein B mediates the formation of pentameric assembly intermediates, whereas the external scaffolding protein D organizes 12 of these intermediates into procapsids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201527c40c52619fffd370637b11e350
https://doi.org/10.1128/jvi.01384-17
https://doi.org/10.1128/jvi.01384-17
Autor:
Bentley A. Fane, Aaron P. Roznowski
Although the ϕX174 H protein is monomeric during procapsid morphogenesis, 10 proteins oligomerize to form a DNA translocating conduit (H-tube) for penetration. However, the timing and location of H-tube formation are unknown. The H-tube's highly rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78b381edbf9d290fd576b778bd1e0c4
https://europepmc.org/articles/PMC4988169/
https://europepmc.org/articles/PMC4988169/
Publikováno v:
Molecular biology and evolution. 31(6)
Single-stranded DNA(ssDNA) viral life cycles must balance double-stranded DNA (dsDNA) and ssDNA biosynthesis. Previously published in vitro results suggest that microvirus C and host cell SSB proteins play antagonistic roles to achieve this balance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee68ecdcd05a7742009235cdaae6cb9
https://pubmed.ncbi.nlm.nih.gov/24600050
https://pubmed.ncbi.nlm.nih.gov/24600050
Autor:
David A. Baum, Bret Larget, Aaron P. Roznowski, Raul Correa, John Stanga, Guoping Shu, Brian P. Dilkes
Summary •Transgenomics is the process of introducing genomic clones from a donor species into a recipient species and then screening the resultant transgenic lines for phenotypes of interest. This method might allow us to find genes involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8d6368107b7234942e645382d0f628
https://europepmc.org/articles/PMC3253215/
https://europepmc.org/articles/PMC3253215/