Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Aaron N. Reifler"'
Autor:
Aaron N. Reifler, Kwoon Y. Wong
Publikováno v:
Journal of neuroscience methods. 384
Constituting about 5 % of mouse retinal ganglion cells (RGCs), intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin (gene symbol Opn4) and drive such photoresponses as pupil constriction, melatonin suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b9191d772e93a733e5146d5f98250f
https://pubmed.ncbi.nlm.nih.gov/36470470
https://pubmed.ncbi.nlm.nih.gov/36470470
Publikováno v:
Curr Eye Res
PURPOSE: Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain the photopigment melanopsin and can signal light continuously for many hours. Melanopsin is excited when its chromophore 11-cis-retinal absorbs a photon and becomes all-tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d1f804a39227520c84130efe5ab431
https://doi.org/10.1080/02713683.2020.1815793
https://doi.org/10.1080/02713683.2020.1815793
Autor:
Elizabeth R. Jaeckel, Aaron N. Reifler, Melanie M. Schroeder, Kwoon Y. Wong, Xiwu Zhao, Andrew P. Chervenak
Publikováno v:
The Journal of General Physiology
Visual stimuli of different frequencies are encoded in the retina using transient and sustained responses. Zhao et al. describe the different strategies that are used by four types of retinal ganglion cells to shape photoresponse kinetics.
Retin
Retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85ba01e99a0dffbb1c02cb88829f9cb
https://doi.org/10.1085/jgp.201611720
https://doi.org/10.1085/jgp.201611720
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Intrinsically photosensitive retinal ganglion cells (ipRGCs) signal not only centrally to non-image-forming visual centers of the brain but also intraretinally to amacrine interneurons through gap junction electrical coupling, potentially mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593f6b55386d3d2ad492abf06b3c020f
https://doi.org/10.1167/iovs.62.1.10
https://doi.org/10.1167/iovs.62.1.10
Autor:
Elizabeth R. Jaeckel, Andrew M. Lynch, Benjamin Y. Li, Rebecca D. Wachter, Aaron N. Reifler, Kwoon Y. Wong, Benjamin S. Meyers, Zachary D. Demertzis, Brian A. Benenati, Fady S. Abufarha, Michael P. Flannery, Michael E. Dolikian, Andrew P. Chervenak
Publikováno v:
Current Biology. 25(21):2763-2773
SummaryRetinal neurons exhibit sustained versus transient light responses, which are thought to encode low- and high-frequency stimuli, respectively. This dichotomy has been recognized since the earliest intracellular recordings from the 1960s, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4761c784626857e67ddcbe64f8ff5cf0
Autor:
Ann E. Davidson, Xingli Li, Nesrin Sabha, Susan V. Brooks, Ana Buj-Bello, Gilbert Di Paolo, Nadine M. Eltayeb, James J. Dowling, Claudia Dall'Armi, Hernan Gonorazky, Jonathan R. Volpatti, Aaron N. Reifler, Eva L. Feldman
Publikováno v:
J Clin Invest
J Clin Invest, 2016, 126 (9), pp.3613-25. ⟨10.1172/JCI86841⟩
J Clin Invest, 2016, 126 (9), pp.3613-25. ⟨10.1172/JCI86841⟩
International audience; Myotubular myopathy (MTM) is a devastating pediatric neuromuscular disorder of phosphoinositide (PIP) metabolism resulting from mutations of the PIP phosphatase MTM1 for which there are no treatments. We have previously shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4b9088bf330169545bfee494a8d9db
https://hal.archives-ouvertes.fr/hal-02881017
https://hal.archives-ouvertes.fr/hal-02881017
Autor:
Michael E. Dolikian, Aaron N. Reifler, L. Samantha Zhang, Kwoon Y. Wong, Daniel B. Forger, Olivia J. Walch
Intrinsically photosensitive retinal ganglion cells (ipRGCs) mediate both image-forming vision and non-image-forming visual responses such as pupillary constriction and circadian photoentrainment. Five types of ipRGCs, named M1–M5, have been discov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3433d71be94fdcda633d6a0b84aec91e
https://europepmc.org/articles/PMC4737408/
https://europepmc.org/articles/PMC4737408/
Autor:
Andrew P. Chervenak, Pamela K. Cornuet, Michael D. West, Igor O. Nasonkin, Aaron N. Reifler, Kwoon Y. Wong, Ratnesh K. Singh, Ramya Krishna Mallela
Publikováno v:
Stem cells and development. 24(23)
Stem cell-based therapy of retinal degenerative conditions is a promising modality to treat blindness, but requires new strategies to improve the number of functionally integrating cells. Grafting semidifferentiated retinal tissue rather than progeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5843410c77c6e5b9cad2d8fb797d09
https://pubmed.ncbi.nlm.nih.gov/26283078
https://pubmed.ncbi.nlm.nih.gov/26283078
Autor:
Benjamin Y. Li, Andrew P. Chervenak, Aaron N. Reifler, Xiwu Zhao, Zachary D. Demertzis, Weston Pack, Brian A. Benenati, Fady S. Abufarha, Rebecca D. Wachter, Michael E. Dolikian, Kwoon Y. Wong, Benjamin S. Meyers, Andrew M. Lynch, Eden A. Dulka
Intrinsically photosensitive retinal ganglion cells (ipRGCs) are inner retinal photoreceptors that mediate non-image-forming visual functions, e.g. pupillary constriction, regulation of pineal melatonin release, and circadian photoentrainment. Five t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2b96aad2dd2ef11ce73eed25979fdd
https://europepmc.org/articles/PMC4276437/
https://europepmc.org/articles/PMC4276437/
Autor:
Xingli Li, Joel R. McDade, Aaron N. Reifler, James J. Dowling, Ashley J. Archambeau, Daniel E. Michele, Nesrin Sabha
Publikováno v:
The American journal of pathology. 184(6)
Abnormalities in phosphoinositide metabolism are an emerging theme in human neurodegenerative disease. Myotubular myopathy is a prototypical disorder of phosphoinositide dysregulation that is characterized by profound muscle pathology and weakness an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fd47f03bb24a04eeefb8cf7f63058f
https://pubmed.ncbi.nlm.nih.gov/24726497
https://pubmed.ncbi.nlm.nih.gov/24726497