Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Aaron N. Endsley"'
Autor:
Benben Song, Kalyani Jambunathan, Patrick Kibler, Aaron N. Endsley, Surendra Kumar Nayak, Amit K. Galande
Publikováno v:
Chemical Biology & Drug Design. 86:1433-1437
Hemopressin is a naturally occurring and therapeutically relevant peptide with applications in hypertension, pain, addiction, and obesity. We had previously demonstrated that hemopressin converts into amyloid-like fibrils under aqueous conditions. Ho
Autor:
Mary J. Tanga, Amy C. Shurtleff, Lynne Gilfillan, Sina Bavari, Travis K. Warren, Peter B. Madrid, Robert A. Davey, Aaron N. Endsley, Andrey A. Kolokoltsov, Ian D. Manger, Carol E. Green, Rekha G. Panchal
Publikováno v:
ACS Infectious Diseases. 1:317-326
A systematic screen of FDA-approved drugs was performed to identify compounds with in vitro antiviral activities against Ebola virus (EBOV). Compounds active (>50% viral inhibition and
Autor:
Rebecca J. Abergel, Dahlia D. An, Jonathan A. Villalobos, Taylor A. Choi, Christophe Colas, Joel A. Morales-Rivera, Walter Shinn, Polly Y. Chang, Aaron N. Endsley, Jack E. Dabbs, Deborah I. Bunin
Publikováno v:
Drug Development Research. 76:107-122
The pharmacokinetics and biodistribution of the (14) C-labeled actinide decorporation agent 3,4,3-LI(1,2-HOPO) were investigated in young adult Swiss Webster mice and Sprague Dawley rats, after intravenous, intraperitoneal, and oral dose administrati
Autor:
Krishna Kodukula, M. Travis Harrison, Annalisa D'Andrea, Douglas S. Watson, Fangfang Yin, Jennifer K. Miller, Aaron N. Endsley
Publikováno v:
Probiotics and Antimicrobial Proteins. 5:69-80
Susceptibility to deadly diarrheal diseases is partly due to widespread pediatric vitamin A deficiency. To increase vitamin A coverage in malnourished children, we propose to engineer a probiotic bacterium that will produce β-carotene in the intesti
Autor:
Aaron N. Endsley, Rodney J. Y. Ho
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 61:417-424
BACKGROUND Combination drug therapy has reduced plasma HIV to undetectable levels; however, drug-sensitive virus persists in patients' lymphoid tissue. We have reported significant lymphoid tissue drug localization with indinavir-associated lipid nan
Publikováno v:
BMC Cancer
Background Success of cancer prodrugs relying on a foreign gene requires specific delivery of the gene to the cancer, and improvements such as higher level gene transfer and expression. Attaining these objectives will be facilitated in preclinical st
Autor:
Aaron N. Endsley, Rodney J. Y. Ho
Publikováno v:
The AAPS Journal. 14:225-235
Human immunodeficiency virus (HIV) persists in lymph nodes and lymphoid tissues even during aggressive drug treatment, likely due to insufficient drug concentrations at this site. Therefore, to eliminate this residual virus, methods that enhance lymp
Autor:
Rodney J. Y. Ho, Aaron N. Endsley
Publikováno v:
Journal of Medical Primatology. 41:52-59
Background Although the interactions of cellular cytidine deaminase A3G and viral infection factor (vif) of human immunodeficiency virus (HIV) were reported, regulation of A3G after in vivo HIV infection and disease progression is not known.
Publikováno v:
Current HIV Research. 6:401-410
According to the World Health Organization's 2007 estimates, close to 33 million people worldwide are living with HIV/AIDS. Over the past two decades, significant progress has been made in understanding HIV pathogenesis and disease progression, which
Autor:
Taylor A, Choi, Aaron N, Endsley, Deborah I, Bunin, Christophe, Colas, Dahlia D, An, Joel A, Morales-Rivera, Jonathan A, Villalobos, Walter M, Shinn, Jack E, Dabbs, Polly Y, Chang, Rebecca J, Abergel
Publikováno v:
Drug development research. 76(3)
The pharmacokinetics and biodistribution of the (14) C-labeled actinide decorporation agent 3,4,3-LI(1,2-HOPO) were investigated in young adult Swiss Webster mice and Sprague Dawley rats, after intravenous, intraperitoneal, and oral dose administrati