Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Aaron Monte"'
Autor:
William R. Schwan, Jill M. Kolesar, M. Shahjahan Kabir, Edmund J. Elder, Jeffrey B. Williams, Rachel Minerath, James M. Cook, Christopher M. Witzigmann, Aaron Monte, Tricia Flaherty
Publikováno v:
Antibiotics, Vol 4, Iss 4, Pp 617-626 (2015)
Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC50 (125 μg/mL) in vitr
Externí odkaz:
https://doaj.org/article/226c22b06b6c46e8be3d487cad17bc9f
Publikováno v:
Cosmetics, Vol 5, Iss 3, p 45 (2018)
Cosmetic practices that use skin-lightening agents to obtain desired skin tones or treat pigment abnormalities have been popular worldwide. However, the molecular and cellular mechanisms of these agents are still largely unknown. Here we identified a
Externí odkaz:
https://doaj.org/article/f637549954fc4871ab81a2b9d6629f9c
Autor:
William R. Schwan, Rebecca Polanowski, Paul M. Dunman, Sara Medina-Bielski, Michelle Lane, Marc Rott, Lauren Lipker, Amy Wescott, Aaron Monte, James M. Cook, Douglas D. Baumann, V.V.N. Phani Babu Tiruveedhula, Christopher M. Witzigmann, Cassandra Mikel, Md Toufiqur Rahman
Publikováno v:
Antibiotics, Vol 6, Iss 3, p 17 (2017)
The mechanism of action for a new lead stilbene compound coded SK-03-92 with bactericidal activity against methicillin-resistant Staphylococcus aureus (MRSA) is unknown. To gain insight into the killing process, transcriptional profiling was performe
Externí odkaz:
https://doaj.org/article/2b79c41766a14937a9b1eef60589aabb
Publikováno v:
Cosmetics
Volume 5
Issue 3
Cosmetics, Vol 5, Iss 3, p 45 (2018)
Volume 5
Issue 3
Cosmetics, Vol 5, Iss 3, p 45 (2018)
Cosmetic practices that use skin-lightening agents to obtain desired skin tones or treat pigment abnormalities have been popular worldwide. However, the molecular and cellular mechanisms of these agents are still largely unknown. Here we identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc60092d3ab9259449c5707a067c2ee4
Autor:
Edmund J. Elder, Rachel Minerath, Christopher M. Witzigmann, James M. Cook, Jeffrey B. Williams, Aaron Monte, William R. Schwan, M. Shahjahan Kabir, Jill M. Kolesar, Tricia Flaherty
Publikováno v:
Antibiotics, Vol 4, Iss 4, Pp 617-626 (2015)
Antibiotics
Antibiotics
Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC50 (125 μg/mL) in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e3cab8b34105d256f050c30d6f2497
http://www.mdpi.com/2079-6382/4/4/617
http://www.mdpi.com/2079-6382/4/4/617
Autor:
Marc Rott, Christopher M. Witzigmann, Lauren Lipker, Michelle Lane, V. V. N. Phani Babu Tiruveedhula, William R. Schwan, Douglas D Baumann, Rebecca Polanowski, Paul M. Dunman, Cassandra Mikel, Sara Medina-Bielski, Toufiqur Rahman, Amy Wescott, James M. Cook, Aaron Monte
Publikováno v:
Antibiotics
Antibiotics; Volume 6; Issue 3; Pages: 17
Antibiotics, Vol 6, Iss 3, p 17 (2017)
Antibiotics; Volume 6; Issue 3; Pages: 17
Antibiotics, Vol 6, Iss 3, p 17 (2017)
The mechanism of action for a new lead stilbene compound coded SK-03-92 with bactericidal activity against methicillin-resistant Staphylococcus aureus (MRSA) is unknown. To gain insight into the killing process, transcriptional profiling was performe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d011d6345483aee5fb684974d643f9c7
http://europepmc.org/articles/PMC5617981
http://europepmc.org/articles/PMC5617981
Publikováno v:
Toxicology and applied pharmacology. 337
Melanoma is the most aggressive form of skin cancer. Current challenges to melanoma therapy include the adverse effects from immunobiologics, resistance to drugs targeting the MAPK pathway, intricate interaction of many signal pathways, and cancer he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9e40e448dc8adb014f2cb8f807a9d5
https://pubmed.ncbi.nlm.nih.gov/29042215
https://pubmed.ncbi.nlm.nih.gov/29042215
Autor:
Qian Wang, Fuhang Song, Xue Xiao, Pei Huang, Li Li, Aaron Monte, Wael M. Abdel-Mageed, Jian Wang, Hui Guo, Wenni He, Feng Xie, Huanqin Dai, Miaomiao Liu, Caixia Chen, Hao Xu, Mei Liu, Andrew M. Piggott, Xueting Liu, Robert J. Capon, Lixin Zhang
Publikováno v:
Angewandte Chemie. 125:1269-1272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f14fef55c8084391ec4ad6cc638067a3
https://doi.org/10.1002/ange.201208801
https://doi.org/10.1002/ange.201208801
Autor:
David R. Sherman, M. Shahjahan Kabir, Rebecca Polanowski, Sarah M. Krueger, William R. Schwan, Ojas A. Namjoshi, Aaron Monte, James M. Cook, Ranjit Verma, Marc Rott
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:4178-4186
Novel acrylic acid ethyl ester derivatives were synthesized and evaluated as potential agents against Mycobacterium species. A versatile and efficient copper-catalyzed coupling process was developed and used to prepare a library of substituted acryli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0218dc3f6e90165dc7999e257cd4d3
https://doi.org/10.1016/j.bmc.2010.05.016
https://doi.org/10.1016/j.bmc.2010.05.016
Autor:
Rebecca Polanowski, Kurt D. Reed, Sarah M. Krueger, William R. Schwan, Marc Rott, Kathleen C. Engelbrecht, Mary E. Stemper, Aaron Monte, M. Shahjahan Kabir, David R. Sherman, James M. Cook, Rachel Ignasiak
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Graphical abstract Substituted stilbene, phenoxystyrene, and phenothiostyrene analogs of an antimicrobial natural product E-stilbene were synthesized and assayed for the ability to inhibit the growth of clinically significant bacteria.
An antimi
An antimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d11eb8c685df4bc1d6cadf00cbeacb
https://doi.org/10.1016/j.bmcl.2008.09.085
https://doi.org/10.1016/j.bmcl.2008.09.085