Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Aaron McKenna"'
Autor:
Aqsa Ameer, Youqi Cheng, Farrukh Saleem, Uzma, Aaron McKenna, Anne Richmond, Ozan Gundogdu, William T. Sloan, Sundus Javed, Umer Zeeshan Ijaz
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
In recent years, there has been an unprecedented advancement in in situ analytical approaches that contribute to the mechanistic understanding of microbial communities by explicitly incorporating ecology and studying their assembly. In this study, we
Externí odkaz:
https://doaj.org/article/e4e42900423445418e84d7fec1abd3f4
Autor:
Aaron McKenna, Umer Zeeshan Ijaz, Carmel Kelly, Mark Linton, William T. Sloan, Brian D. Green, Ursula Lavery, Nick Dorrell, Brendan W. Wren, Anne Richmond, Nicolae Corcionivoschi, Ozan Gundogdu
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background The factors affecting host-pathogen ecology in terms of the microbiome remain poorly studied. Chickens are a key source of protein with gut health heavily dependent on the complex microbiome which has key roles in nutrient assimil
Externí odkaz:
https://doaj.org/article/7f04c58a330f421e87db3c6300768709
Autor:
Ali Sinan Köksal, Kirsten Beck, Dylan R. Cronin, Aaron McKenna, Nathan D. Camp, Saurabh Srivastava, Matthew E. MacGilvray, Rastislav Bodík, Alejandro Wolf-Yadlin, Ernest Fraenkel, Jasmin Fisher, Anthony Gitter
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3607-3618 (2018)
Summary: We present a method for automatically discovering signaling pathways from time-resolved phosphoproteomic data. The Temporal Pathway Synthesizer (TPS) algorithm uses constraint-solving techniques first developed in the context of formal verif
Externí odkaz:
https://doaj.org/article/48caac5bc5e443d090361032f80a4b17
Autor:
Aaron McKenna, Jay Shendure
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-6 (2018)
Abstract Background Genome-wide knockout studies, noncoding deletion scans, and other large-scale studies require a simple and lightweight framework that can quickly discover and score thousands of candidate CRISPR guides targeting an arbitrary DNA s
Externí odkaz:
https://doaj.org/article/439c9cac1b1f486194bceaa179c7890f
Autor:
Umer Zeeshan Ijaz, Lojika Sivaloganathan, Aaron McKenna, Anne Richmond, Carmel Kelly, Mark Linton, Alexandros Ch. Stratakos, Ursula Lavery, Abdi Elmi, Brendan W. Wren, Nick Dorrell, Nicolae Corcionivoschi, Ozan Gundogdu
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Chickens are a key food source for humans yet their microbiome contains bacteria that can be pathogenic to humans, and indeed potentially to chickens themselves. Campylobacter is present within the chicken gut and is the leading cause of bacterial fo
Externí odkaz:
https://doaj.org/article/5bdf85f8ce67462693b06f3293fad53b
Autor:
Nompilo Sibanda, Aaron McKenna, Anne Richmond, Steven C. Ricke, Todd Callaway, Alexandros Ch. Stratakos, Ozan Gundogdu, Nicolae Corcionivoschi
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Poultry is frequently associated with campylobacteriosis in humans, with Campylobacter jejuni being the most usual Campylobacter associated with disease in humans. Far-reaching research on Campylobacter was undertaken over the past two decades. This
Externí odkaz:
https://doaj.org/article/8e9d725648d44aeb93c35ee9a13083c9
Autor:
Chelsea Place Johnson, Ivana K Kim, Bita Esmaeli, Ali Amin-Mansour, Daniel J Treacy, Scott L Carter, Eran Hodis, Nikhil Wagle, Sara Seepo, Xiaoxing Yu, Anne Marie Lane, Evangelos S Gragoudas, Francisca Vazquez, Elizabeth Nickerson, Kristian Cibulskis, Aaron McKenna, Stacey B Gabriel, Gad Getz, Eliezer M Van Allen, Peter A C 't Hoen, Levi A Garraway, Scott E Woodman
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178189 (2017)
To further our understanding of the somatic genetic basis of uveal melanoma, we sequenced the protein-coding regions of 52 primary tumors and 3 liver metastases together with paired normal DNA. Known recurrent mutations were identified in GNAQ, GNA11
Externí odkaz:
https://doaj.org/article/01422be2fed14a589ff0261b957762c5
Publikováno v:
ACS Synthetic Biology. 11:2238-2246
Recombinant DNA is a fundamental tool in biotechnology and medicine. These DNA sequences are often built, replicated, and delivered in the form of plasmids. Validation of these plasmid sequences is a critical and time-consuming step, which has been d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed36214acbad7f747a2d1d9c99ba11ee
https://doi.org/10.1021/acssynbio.2c00126
https://doi.org/10.1021/acssynbio.2c00126
Autor:
Elizabeth Dong Nguyen, Vahid Nikoonejad Fard, Bernard Y. Kim, Sarah Collins, Miranda Galey, Branden R. Nelson, Paul Wakenight, Simone M. Gable, Aaron McKenna, Theo K. Bammler, Jim MacDonald, Daryl M. Okamura, Jay Shendure, David R. Beier, Jan Marino Ramirez, Mark W. Majesky, Kathleen J. Millen, Marc Tollis, Danny E. Miller
There is increasing interest in the African spiny mouse (Acomys cahirinus) as a model organism because of its ability for regeneration of tissue after injury in skin, muscle, and internal organs such as the kidneys. A high-quality reference genome is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccccecf4aa9964387b04c41961eb88f4
https://doi.org/10.1101/2023.04.03.535372
https://doi.org/10.1101/2023.04.03.535372
Autor:
Levi A. Garraway, Jennifer A. Wargo, Keith T. Flaherty, Scott L. Carter, Stacey B. Gabriel, Gad Getz, Sheila Fisher, Donald P. Lawrence, Eran Hodis, Gregory Kryukov, Kristian Cibulskis, Aaron McKenna, Cory M. Johannessen, Danielle Perrin, Kristin Anderka, Dennis C. Friedrich, Deborah N. Farlow, Ryan J. Sullivan, Eva M. Goetz, Mara Rosenberg, Amaro Taylor-Weiner, Zachary A. Cooper, Dennie T. Frederick, Daniel J. Treacy, Eliezer M. Van Allen, Nikhil Wagle
XLSX file 3569K, Change in Cancer Cell Fraction for all SNVs and Indels in All Samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2deea5c2c969e4a862f7cb47d2a497f3
https://doi.org/10.1158/2159-8290.22530000
https://doi.org/10.1158/2159-8290.22530000