Výsledky vyhledávání - "Aaron Mackey"

Supplementary Figure Legend from Synthetic Lethal Screening with Small-Molecule Inhibitors Provides a Pathway to Rational Combination Therapies for Melanoma

Autor: Daniel Gioeli, Michael J. Weber, Aaron Mackey, Karin Jensen, Brian J. Capaldo, Mark Axelrod, Devin G. Roller

PDF file, 72K.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2af2eb7ceeda8c40ebc3fd14f8a70a
https://doi.org/10.1158/1535-7163.22497996

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Data from Synthetic Lethal Screening with Small-Molecule Inhibitors Provides a Pathway to Rational Combination Therapies for Melanoma

Autor: Daniel Gioeli, Michael J. Weber, Aaron Mackey, Karin Jensen, Brian J. Capaldo, Mark Axelrod, Devin G. Roller

Recent data show that extracellular signals are transmitted through a network of proteins rather than hierarchical signaling pathways, suggesting that the inhibition of a single component of a canonical pathway is insufficient for the treatment of ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5132c624f0ec19884130743959be8825
https://doi.org/10.1158/1535-7163.c.6535764.v1

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Supplementary Figure 1 from Synthetic Lethal Screening with Small-Molecule Inhibitors Provides a Pathway to Rational Combination Therapies for Melanoma

Autor: Daniel Gioeli, Michael J. Weber, Aaron Mackey, Karin Jensen, Brian J. Capaldo, Mark Axelrod, Devin G. Roller

PDF file, 428K, The combination of sorafenib and diclofenac causes cell death.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b556e5ee766cee90e16befefbf6aad
https://doi.org/10.1158/1535-7163.22497999

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Abstract 137: The Response of an in vitro Cynomolgus Macaque System to Statin Treatments Mirrors the Human in vitro System and Clinical Outcomes

Autor: Michael Simmers, Ryan Feaver, Jim Turk, Banumathi Cole, M Sol Collado, Erica Berzin, Mark Lawson, Aaron Mackey, David Manka, Brian Wamhoff, Charles W Qualls, Brett Blackman

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 34

Introduction: There is an urgent unmet need to improve the predictive value of animal and in vitro systems for drug development. The purpose of this study was to develop an in vitro vascular system that reflects the in vivo biology of the cynomolgus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a4da70bb1afe89fda5f864eb3259ba1
https://doi.org/10.1161/atvb.34.suppl_1.137

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The Judicial Check on Classification: How the Freedom of Information Act Can Limit Government Secrets

Autor: Aaron Mackey

Publikováno v: SSRN Electronic Journal.

Recent disclosure of classified materials demonstrate that government is conducting programs that impact our civil liberties in secret or sometimes withholding innocuous info that is embarrassing to government. At the same time, the mountain of gover

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d26e1e48f733c9f550cd3dd8eb733ad6
https://doi.org/10.2139/ssrn.2468118

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DNA Variants in NOS3 Are Associated with Improved Small Artery Elasticity and Decreased Systolic Blood Pressure in Asymptomatic Individuals

Autor: Jennifer L. Hall, Natalia Florez, Marj Carlson, Sara Saul, Mark Lawson, Aaron Mackey, Joao Lima, Jay Cohn, Stephen S. Rich, Wei Zhong, Gregory Grandits, Daniel A. Duprez

Publikováno v: Journal of Cardiac Failure. 17:S34

Fourteen miRNA transcripts were quantified following reverse transcription and realtime polymerase chain reaction; expression levels were normalized to an internal control. After testing for normality, group comparisons were performed using a ttest.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37da4651aa3a050947e999212982c62d
https://doi.org/10.1016/j.cardfail.2011.06.114

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