Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aaron M. Koenig"'
Autor:
Bianca A Trombetta, Becky C Carlyle, Aaron M Koenig, Leslie M Shaw, John Q Trojanowski, David A Wolk, Joseph J Locascio, Steven E Arnold
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193707 (2018)
Alzheimer's disease (AD) is a complex neurodegenerative disease driven by multiple interacting pathophysiological processes that ultimately results in synaptic loss, neuronal death, and dementia. We implemented a fit-for-purpose modeled approach to q
Externí odkaz:
https://doaj.org/article/9f12bf63a7ef4310b58a6a0ca0f6d16e
Publikováno v:
FOCUS. 16:164-172
This article reviews the current evidence base for biomarkers of the most common causes of dementia in later life: Alzheimer’s disease (AD), frontotemporal lobar degenerations, Lewy body dementias, and vascular cognitive impairment and dementia. Bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dcf138ec64cc1da09682dfda57b2596
https://doi.org/10.1176/appi.focus.20170048
https://doi.org/10.1176/appi.focus.20170048
Autor:
Suzanne Craft, Rexford S. Ahima, David M. Holtzman, Aaron M. Koenig, Shannon L. Macauley-Rambach, Luke E. Stoeckel, Zoe Arvanitakis, Steven E. Arnold, Christoph Buettner, Sam Gandy, David M. Nathan, Hoau Yan Wang
Publikováno v:
Nature Reviews Neurology. 14:168-181
Considerable overlap has been identified in the risk factors, comorbidities and putative pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and type 2 diabetes mellitus (T2DM), two of the most pressing epidemics of our t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1404c6724d819d8d99a020cc7cdcbb45
https://doi.org/10.1038/nrneurol.2017.185
https://doi.org/10.1038/nrneurol.2017.185
Publikováno v:
Medical Devices (Auckland, N.Z.)
Background The USA devotes roughly $200 billion (6%) of annual national health expenditures to medical devices. A substantial proportion of this spending occurs during orthopedic (eg, hip and knee) arthroplasties – two high-volume hospital procedur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d638916b11e3c9d27a4c23bf9ac65fba
https://doi.org/10.2147/mder.s151647
https://doi.org/10.2147/mder.s151647
Autor:
Victoria J. Williams, Rabab Z. Jafri, Rexford S. Ahima, David H. Salat, Becky C. Carlyle, Aaron M. Koenig, Chase D Wennick, Laya Ekhlaspour, Steven Russell, Bianca A. Trombetta, Steven E. Arnold
Publikováno v:
JCI Insight. 4
BACKGROUND There is growing evidence to suggest that the brain is an important target for insulin action, and that states of insulin resistance may extend to the CNS with detrimental effects on cognitive functioning. Although the effect of systemic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6526087e2bcd8c57c4663a86870156ba
https://doi.org/10.1172/jci.insight.129700
https://doi.org/10.1172/jci.insight.129700
A growing body of evidence suggests that there is significant overlap in risk, comorbidity, and putative pathophysiological mechanisms across type 2 diabetes (T2D) and dementia owing to Alzheimer's disease (AD). In this chapter, we (1) describe the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d9f47eeb705eaa1f04cee0f60b5d476
https://doi.org/10.1016/b978-0-12-809454-9.00008-1
https://doi.org/10.1016/b978-0-12-809454-9.00008-1
Autor:
Erin L. Abner, Steven E. Arnold, Zoe Arvanitakis, Eugene J. Barrett, Richard Beare, Michal Schnaider Beeri, Tina Brinkley, David G. Bruce, Michele Callisaya, Suzanne Craft, Karthik Dhananjayan, Mark A. Espeland, Josephine Forbes, Ithamar Ganmore, Sarah M. Gray, Deborah R. Gustafson, Aaron M. Koenig, Samy I. McFarlane, Chris Moran, Gerald Münch, Peter T. Nelson, Thanh Phan, Jeremy J. Pruzin, Dana M. Small, Velandai Srikanth, Luke E. Stoeckel, Brooke J. Wanrooy, Connie H.Y. Wong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47139650e345e04855f14cffd263ed01
https://doi.org/10.1016/b978-0-12-809454-9.01002-7
https://doi.org/10.1016/b978-0-12-809454-9.01002-7
Autor:
Steven E. Arnold, Leslie M. Shaw, Joseph J. Locascio, Bianca A. Trombetta, John Q. Trojanowski, Becky C. Carlyle, Aaron M. Koenig, David A. Wolk
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193707 (2018)
PLoS ONE
PLoS ONE
Objective Alzheimer’s disease (AD) is a complex neurodegenerative disease driven by multiple interacting pathophysiological processes that ultimately results in synaptic loss, neuronal death, and dementia. We implemented a fit-for-purpose modeled a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9365cfa8b93965a6f4b8cc9141958c23
http://europepmc.org/articles/PMC5837100?pdf=render
http://europepmc.org/articles/PMC5837100?pdf=render
Autor:
Isaac J. DeLozier, Steven E. Arnold, Megan M Marron, James T. Becker, Meryl A. Butters, Michelle D. Zmuda, Charles F. Reynolds, Stewart J. Anderson, Amy E. Begley, Aaron M. Koenig
Publikováno v:
Journal of Alzheimer's Disease. 45:175-185
Late-life depression (LLD, major depression occurring in an adult 60 years or older) is a common condition that frequently presents with cognitive impairment. Up to half of individuals with LLD are estimated to have cognitive impairment greater than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28199fd76e56407a917205e119f9746d
https://doi.org/10.3233/jad-148006
https://doi.org/10.3233/jad-148006
Autor:
Sharon X. Xie, Dawn Mechanic-Hamilton, Long Xie, Anne R. Cappola, John A. Detre, Steven E. Arnold, Aaron M. Koenig, Martha F. Combs, David A. Wolk
Publikováno v:
Alzheimer disease and associated disorders. 31(2)
Epidemiological studies have identified a robust association between type II diabetes mellitus and Alzheimer disease (AD), and neurobiological studies have suggested the presence of central nervous system insulin resistance in individuals with AD. Gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e6024d95c382266667c60274d77956
https://pubmed.ncbi.nlm.nih.gov/28538088
https://pubmed.ncbi.nlm.nih.gov/28538088