Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Aaron M. Gibson"'
Autor:
Emily D. Morales, Yongping Yue, Thais B. Watkins, Jin Han, Xiufang Pan, Aaron M. Gibson, Bryan Hu, Omar Brito‐Estrada, Gang Yao, Catherine A. Makarewich, Gopal J. Babu, Dongsheng Duan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 3 (2023)
Background Cardiomyopathy is a leading health threat in Duchenne muscular dystrophy (DMD). Cytosolic calcium upregulation is implicated in DMD cardiomyopathy. Calcium is primarily removed from the cytosol by the sarcoendoplasmic reticulum calcium ATP
Externí odkaz:
https://doaj.org/article/9a37d2fd69cd4921bac7c1d3539ed8f5
Autor:
Richard J. Gilbert, Thomas C. Irving, David M. Warshaw, Sakthivel Sadayappan, Weikang Ma, James W. McNamara, Gina Kuffel, Mayandi Sivaguru, Diederik W. D. Kuster, Paul M.L. Janssen, Burns C. Blaxall, Mohit Kumar, Dana M. Leichter, John N. Lorenz, Kyounghwan Lee, Michael J. Previs, Roger Craig, Michelle L. Nieman, Brian Lin, Thomas L. Lynch, Rohit R. Singh, Pieter P. de Tombe, Aaron M. Gibson, Michael J. Zilliox, Owen P. Leary
Publikováno v:
Lynch, T L, Kumar, M, McNamara, J W, Kuster, D W D, Sivaguru, M, Singh, R R, Previs, M J, Lee, K H, Kuffel, G, Zilliox, M J, Lin, B L, Ma, W, Gibson, A M, Blaxall, B C, Nieman, M L, Lorenz, J N, Leichter, D M, Leary, O P, Janssen, P M L, de Tombe, P P, Gilbert, R J, Craig, R, Irving, T, Warshaw, D M & Sadayappan, S 2021, ' Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility ', Journal of Molecular and Cellular Cardiology, vol. 156, pp. 33-44 . https://doi.org/10.1016/j.yjmcc.2021.03.009
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2021, 156, pp.33-44. ⟨10.1016/j.yjmcc.2021.03.009⟩
J Mol Cell Cardiol
Journal of Molecular and Cellular Cardiology, 156, 33-44. Academic Press Inc.
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, 2021, 156, pp.33-44. ⟨10.1016/j.yjmcc.2021.03.009⟩
J Mol Cell Cardiol
Journal of Molecular and Cellular Cardiology, 156, 33-44. Academic Press Inc.
International audience; Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) regulates cardiac contraction through modulation of actomyosin interactions mediated by the protein's amino terminal (N′)-region (C0-C2 domains, 358 amino acids).
Autor:
Kayla G Kinker, Aaron M Gibson, Stacey A Bass, Brandy P Day, Jingyuan Deng, Mario Medvedovic, Julio A Landero Figueroa, Gurjit K Khurana Hershey, Weiguo Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85148 (2014)
Levels of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, are increased in lung, sputum, exhaled breath condensate and plasma samples from asthma patients. ADMA is metabolized primarily by dimethylarginine dimeth
Externí odkaz:
https://doaj.org/article/020794c0957f4bf7a8c6c56f21371af2
Autor:
Catherine A. Makarewich, Rhonda Bassel-Duby, John R. McAnally, Svetlana Bezprozvannaya, Thomas P Matthews, Sean J. Morrison, Eric N. Olson, Misty Martin, Amir Z Munir, Aaron M. Gibson
Publikováno v:
Circulation. 142
Introduction: Emerging evidence suggests that many RNA molecules currently annotated as noncoding contain short open reading frames that code for functional small proteins called microproteins. Microproteins play critical roles in a diverse range of
Autor:
Gerald B Lee, Eric B Brandt, Chang Xiao, Aaron M Gibson, Timothy D Le Cras, Lou Ann S Brown, Anne M Fitzpatrick, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60632 (2013)
Diesel exhaust particle (DEP) exposure enhances allergic inflammation and has been linked to the incidence of asthma. Oxidative stress on the thiol molecules cysteine (Cys) and glutathione (GSH) can promote inflammatory host responses. The effect of
Externí odkaz:
https://doaj.org/article/de105367b1c04fa7ae99ff3af3d59e37
Autor:
Lisa J Martin, Jayanta Gupta, Soma S S K Jyothula, Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Tia L Patterson, Mark B Ericksen, Hua He, Aaron M Gibson, Tesfaye M Baye, Sushil Amirisetty, Anna M Tsoras, Youbao Sha, N Tony Eissa, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33454 (2012)
Rationale and objectiveAutophagy is a cellular process directed at eliminating or recycling cellular proteins. Recently, the autophagy pathway has been implicated in immune dysfunction, the pathogenesis of inflammatory disorders, and response to vira
Externí odkaz:
https://doaj.org/article/387c3faf46704aaca8344c0be9ea39da
Autor:
Melinda Butsch Kovacic, Jocelyn M Biagini Myers, Ning Wang, Lisa J Martin, Mark Lindsey, Mark B Ericksen, Hua He, Tia L Patterson, Tesfaye M Baye, Dara Torgerson, Lindsey A Roth, Jayanta Gupta, Umasundari Sivaprasad, Aaron M Gibson, Anna M Tsoras, Donglei Hu, Celeste Eng, Rocío Chapela, José R Rodríguez-Santana, William Rodríguez-Cintrón, Pedro C Avila, Kenneth Beckman, Max A Seibold, Chris Gignoux, Salma M Musaad, Weiguo Chen, Esteban González Burchard, Gurjit K Khurana Hershey
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23714 (2011)
Asthma is a chronic inflammatory disease with a strong genetic predisposition. A major challenge for candidate gene association studies in asthma is the selection of biologically relevant genes.Using epithelial RNA expression arrays, HapMap allele fr
Externí odkaz:
https://doaj.org/article/5f4cc418e1864f3d8f3a32d8a027af35
Autor:
Tarek Alsaied, Farhan Zafar, R. Scott Baker, Kyle W. Riggs, Sithara Raju Ponny, Katherine E. Yutzey, Victoria Moore, Emma J Agnew, Gabriela Matos Ortiz, Nivedhitha Velayutham, Aaron M. Gibson, Christina M. Alfieri
Studies in mice show a brief neonatal period of cardiac regeneration with minimal scar formation. Less is known about reparative mechanisms in large mammals. A transient cardiac injury approach (ischemia/reperfusion, IR) was used in weaned postnatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c36330df10b86932b9c3e3426ee6c2d
https://doi.org/10.1101/773218
https://doi.org/10.1101/773218
Inhibiting fibronectin attenuates fibrosis and improves cardiac function in a model of heart failure
Autor:
Jeffery D. Molkentin, Ane M. Salvador, Jiuzhou Huo, Tony DeFalco, Allison E. Schafer, Charles Perkins, Iñigo Valiente-Alandi, Francisco J. Carrillo-Salinas, Sarah J. Potter, Michelle L. Nieman, Tobias G. Schips, Aaron M. Gibson, Pilar Alcaide, John N. Lorenz, Burns C. Blaxall, Michelle A. Sargent
Background: Fibronectin (FN) polymerization is necessary for collagen matrix deposition and is a key contributor to increased abundance of cardiac myofibroblasts (MFs) after cardiac injury. We hypothesized that interfering with FN polymerization or i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9362b2b179c9f92b2cf4e64a7f4e513
https://europepmc.org/articles/PMC6186194/
https://europepmc.org/articles/PMC6186194/