Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Aaron M Shapiro"'
Autor:
Danielle M. Drake, Kian Afsharian, Benjamin Or, Aaron M. Shapiro, Michelle L. Lai, Lutfiya Miller, Peter G. Wells
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103070- (2024)
Although widely known as a tumor suppressor, the breast cancer 1 susceptibility protein (BRCA1) is also important in development, where it regulates fetal DNA repair pathways that protect against DNA damage caused by physiological and drug-enhanced l
Externí odkaz:
https://doaj.org/article/41425faa30ac481d8fe65cebd14ab96d
Autor:
Sandrine A M Mérette, Sébastien Thériault, Lei E C Piramide, Michael D Davis, Aaron M Shapiro
Publikováno v:
Journal of Analytical Toxicology. 47:385-392
Bromazolam is a designer benzodiazepine that was first detected in British Columbia in January 2021. Postmortem cases were analyzed using a comprehensive blood drug screening procedure by liquid chromatography–high-resolution mass spectrometry befo
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 30-38 (2016)
The breast cancer 1 (brca1) gene is associated with breast and ovarian cancers, and heterozygous (+/−) brca1 knockout progeny develop normally, suggesting a negligible developmental impact. However, our results show BRCA1 plays a broader biological
Externí odkaz:
https://doaj.org/article/e2371794ce1c4f46939854edb66cbde3
Autor:
Barbara J. Hawkins, Sandrine A Mérette, Andrew Washbrook, Elizabeth W L Brooks-Lim, Carolyn Maxwell, Aaron M. Shapiro
Publikováno v:
Journal of Forensic Sciences. 67:820-826
Poisoning from consumption of foraged alternative medicine products is an uncommon yet recognized occurrence. Here, presented is the case of a 40-year-old woman who was witnessed to collapse with labored breathing and subsequently died despite emerge
Publikováno v:
Canadian Journal of Addiction. 11:28-32
Autor:
Mark Lysyshyn, Ashraf Amlani, Alert Partnership, Margot Kuo, Kristi Papamihali, Roy Purssell, Aaron M. Shapiro, Jane A. Buxton, Christopher Mill, Sara Young, Bill Spearn
Publikováno v:
Journal of Community Safety and Well-Being. 4:4-9
Illicit drug overdose is a public health issue that leads to significant morbidity and mortality. In order to reduce the harm associated with substance use, emergent issues related to substances and substance use must be addressed in a timely manner,
Autor:
Nazlee Maghsoudi, Cristiana Stefan, Lianping Ti, Aaron M. Shapiro, Karen McDonald, Samuel Tobias, Mark Lysyshyn, M.-J. Milloy, Dan Werb, Daniel Beriault
Publikováno v:
Drug and alcohol reviewReferences. 40(4)
Introduction Novel psychoactive substances (NPS) are increasingly being consumed worldwide, with synthetic cannabinoids and synthetic opioids being the second and third most commonly used NPS, respectively. Certain synthetic cannabinoids can produce
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1965
Reactive oxygen species (ROS) can oxidize cellular macromolecules like DNA, causing DNA damage. The most common form of DNA damage is the 8-oxoguanine (8-oxoG) lesion, typically repaired by the base excision repair (BER) pathway, which is initiated b
Autor:
Allison Marmel, M. Eugenia Socías, Lianping Ti, Aaron M. Shapiro, Samuel Tobias, Richard Laing, Mark Lysyshyn, Matthew K. Laing
Publikováno v:
International Journal of Drug Policy. 93:103169
Background From mid-2018, an increase in novel psychoactive substance (NPS) benzodiazepines was noted on surveillance of the unregulated drug market around Vancouver, British Columbia, Canada. The rise was concordant with an outbreak of atypical over
Publikováno v:
Drug and Alcohol Dependence. 218:108300
Background Non-prescribed benzodiazepine use is increasing in North America, especially among youth. Owing to increasing demand, counterfeit benzodiazepine tablets are mass-produced in clandestine, unregulated environments and sold as legitimate phar