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pro vyhledávání: '"Aaron M Broege"'
Autor:
Adrish Sen, Salmaan A Khan, Ian A. MacNeil, Benjamin E. Rich, Jhomary S Molden, Laura N Davis, Stefano Rossetti, Aaron M Broege, Lance G. Laing
Publikováno v:
Journal of Clinical Oncology. 41:149-149
149 Background: Metastatic castration-resistant prostate cancer (mCRPrC) is characterized by a loss of androgen receptor (AR) sensitivity and oncogenic activation of the PI3K, AKT, and mTOR (PAM) pathway. Loss of the PI3K regulator, PTEN, is frequent