Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues

Autor: Aaron L Fidler, Carl E Darris, Sergei V Chetyrkin, Vadim K Pedchenko, Sergei P Boudko, Kyle L Brown, W Gray Jerome, Julie K Hudson, Antonis Rokas, Billy G Hudson

Publikováno v: eLife, Vol 6 (2017)

The role of the cellular microenvironment in enabling metazoan tissue genesis remains obscure. Ctenophora has recently emerged as one of the earliest-branching extant animal phyla, providing a unique opportunity to explore the evolutionary role of th

Externí odkaz: https://doaj.org/article/e19f2cf7fd724dce8e52fab510ae0f42

Collagen IVα345 dysfunction in glomerular basement membrane diseases. I. Discovery of a COL4A3 variant in familial Goodpasture’s and Alport diseases

Autor: George Haddad, Charles D. Pusey, Agnes B. Fogo, Dale R. Abrahamson, Rudolf P. Wüthrich, Clifford E. Kashtan, Alicia Simmons, Paul A. Voziyan, Fernando C. Fervenza, Sergei P. Boudko, Timo Wagner, Zhao Wei Cui, A. Richard Kitching, Raymond C. Harris, Eric Delpire, Andreas D. Kistler, Johan M. Lorenzen, Ming-Hui Zhao, Aaron L. Fidler, Sergei V. Chetyrkin, Ariana Gaspert, Carsten Bergmann, Oliver Gross, Billy G. Hudson, Maik Grohmann, Marten Segelmark, Harald Seeger, Elena Pokidysheva, Stephen P. McAdoo, Vadim Pedchenko

Publikováno v: The Journal of Biological Chemistry

Diseases of the glomerular basement membrane (GBM), such as Goodpasture’s disease (GP) and Alport syndrome (AS), are a major cause of chronic kidney failure and an unmet medical need. Collagen IVα345 is an important architectural element of the GB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed717b2a810710cfdf2e9dee7466f10
https://doi.org/10.1016/j.jbc.2021.100590

The triple helix of collagens – an ancient protein structure that enabled animal multicellularity and tissue evolution

Autor: Billy G. Hudson, Aaron L. Fidler, Antonis Rokas, Sergei P. Boudko

Publikováno v: Journal of Cell Science. 131

The cellular microenvironment, characterized by an extracellular matrix (ECM), played an essential role in the transition from unicellularity to multicellularity in animals (metazoans), and in the subsequent evolution of diverse animal tissues and or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34f9cb9f2d5c41163d33d248bc88d99
https://doi.org/10.1242/jcs.203950

Author response: Collagen IV and basement membrane at the evolutionary dawn of metazoan tissues

Autor: Billy G. Hudson, Sergei P. Boudko, W. Gray Jerome, Julie K. Hudson, Carl Darris, Aaron L. Fidler, Vadim Pedchenko, Sergei V. Chetyrkin, Antonis Rokas, Kyle L. Brown

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55dc3ed92727805d4bbe8376e3ebbfe8
https://doi.org/10.7554/elife.24176.029

A unique covalent bond in basement membrane is a primordial innovation for tissue evolution

Autor: Billy G. Hudson, Dorin-Bogdan Borza, W. Hayes McDonald, Aaron L. Fidler, Viravuth P. Yin, Cody L. Stothers, Michael T. Ivy, Robert Steele, Travis A Clark, Sergei V. Chetyrkin, Julie K. Hudson, Aspirnauts, Vadim Pedchenko, Roberto M. Vanacore, Gautam Bhave, Kristie L. Rose

Publikováno v: Fidler, AL; Vanacore, RM; Chetyrkin, SV; Pedchenko, VK; Bhave, G; Yin, VP; et al.(2014). A unique covalent bond in basement membrane is a primordial innovation for tissue evolution. Proceedings of the National Academy of Sciences of the United States of America, 111(1), 331-336. doi: 10.1073/pnas.1318499111. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/77k6x5zp

Basement membrane, a specialized ECM that underlies polarized epithelium of eumetazoans, provides signaling cues that regulate cell behavior and function in tissue genesis and homeostasis. A collagen IV scaffold, a major component, is essential for t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1aea0ec2c3ec2273f399be88f37f35
http://www.escholarship.org/uc/item/77k6x5zp