Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Aaron L Miller"'
Autor:
Elizabeth Jaworski, Rose M Langsjoen, Brooke Mitchell, Barbara Judy, Patrick Newman, Jessica A Plante, Kenneth S Plante, Aaron L Miller, Yiyang Zhou, Daniele Swetnam, Stephanea Sotcheff, Victoria Morris, Nehad Saada, Rafael RG Machado, Allan McConnell, Steven G Widen, Jill Thompson, Jianli Dong, Ping Ren, Rick B Pyles, Thomas G Ksiazek, Vineet D Menachery, Scott C Weaver, Andrew L Routh
Publikováno v:
eLife, Vol 10 (2021)
High-throughput genomics of SARS-CoV-2 is essential to characterize virus evolution and to identify adaptations that affect pathogenicity or transmission. While single-nucleotide variations (SNVs) are commonly considered as driving virus adaption, RN
Externí odkaz:
https://doaj.org/article/4d7ebe7fd8ba48a3ba01181583b2b50c
Autor:
Nicholas A Bergren, Sherry Haller, Shannan L Rossi, Robert L Seymour, Jing Huang, Aaron L Miller, Richard A Bowen, Daniel A Hartman, Aaron C Brault, Scott C Weaver
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008102 (2020)
Understanding the circumstances under which arboviruses emerge is critical for the development of targeted control and prevention strategies. This is highlighted by the emergence of chikungunya and Zika viruses in the New World. However, to comprehen
Externí odkaz:
https://doaj.org/article/4eafaa0f120c49e2aa81489a66b94ad9
Autor:
Judith U. Oguzie, Lyudmyla V. Marushchak, Ismaila Shittu, John A. Lednicky, Aaron L. Miller, Haiping Hao, Martha I. Nelson, Gregory C. Gray
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 7, Pp 1425-1429 (2024)
During March and April 2024, we studied dairy cattle specimens from a single farm in Texas, USA, using multiple molecular, cell culture, and next-generation sequencing pathogen detection techniques. Here, we report evidence that highly pathogenic avi
Externí odkaz:
https://doaj.org/article/ee2058c224e24ce29dddde83f17a763e
Autor:
Logan Grimes, Allie Doyle, Aaron L Miller, Richard B Pyles, Gabor Olah, Csaba Szabo, Sarah Hoskinson, Tonyia Eaves-Pyles
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170722 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0166770.].
Externí odkaz:
https://doaj.org/article/6342a3d2e640471ba66991232e542374
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174183 (2017)
Without a glucocorticoid (GC) ligand, the transcription factor glucocorticoid receptor (GR) is largely cytoplasmic, with its GC-binding domain held in high affinity conformation by a cluster of chaperones. Binding a GC causes serial dis- and re-assoc
Externí odkaz:
https://doaj.org/article/778e54e79f0e44a3b913c019d17e630f
Autor:
Logan Grimes, Allie Doyle, Aaron L Miller, Richard B Pyles, Gabor Olah, Csaba Szabo, Sarah Hoskins, Tonyia Eaves-Pyles
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0166770 (2016)
Burn injury is associated with a loss of gut barrier function, resulting in systemic dissemination of gut-derived bacteria and their products. The bacterial protein and TLR5 agonist, flagellin, induces non-specific innate immune responses. Because we
Externí odkaz:
https://doaj.org/article/11bd504fdaec472da04d6cb8f0d74242
Autor:
Richard B Pyles, Kathleen L Vincent, Marc M Baum, Barry Elsom, Aaron L Miller, Carrie Maxwell, Tonyia D Eaves-Pyles, Guangyu Li, Vsevolod L Popov, Rebecca J Nusbaum, Monique R Ferguson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93419 (2014)
There is a pressing need for modeling of the symbiotic and at times dysbiotic relationship established between bacterial microbiomes and human mucosal surfaces. In particular clinical studies have indicated that the complex vaginal microbiome (VMB) c
Externí odkaz:
https://doaj.org/article/48062bfe7092489c901bea811486b4f9
Autor:
Richard B. Pyles, Aaron L. Miller, Randall J. Urban, Melinda Sheffield-Moore, Traver J. Wright, Carrie A. Maxwell, Kathleen M. Randolph, Christopher P. Danesi, Kristen A. McGovern, Jayson Vargas, Peyton Armstrong, Lisa Kreber, Giuliana Cumpa, Kevin Randall, Melissa Morrison, Brent E. Masel
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionPatients who suffer a traumatic brain injury (TBI) often experience chronic and sometimes debilitating sequelae. Recent reports have illustrated both acute and long-term dysbiosis of the gastrointestinal microbiome with significant altera
Externí odkaz:
https://doaj.org/article/ea558d03be1244bc86d3e8cbf31fae31
Autor:
Tonyia Eaves-Pyles, Jignesh Patel, Emma Arigi, Yingzi Cong, Anthony Cao, Nisha Garg, Monisha Dhiman, Richard B. Pyles, Bernard Arulanandam, Aaron L. Miller, Vsevolod L. Popov, Lynn Soong, Eric D. Carlsen, Ciro Coletta, Csaba Szabo, Igor C. Almeida
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 263-275 (2013)
Abstract Cystatin 9 (CST9) is a member of the type 2 cysteine protease inhibitor family, which has been shown to have immunomodulatory effects that restrain inflammation, but its functions against bacterial infections are unknown. Here, we report tha
Externí odkaz:
https://doaj.org/article/35b85162da3a468382874d1d6b7ae4c4
Autor:
Brent E. Masel, Kathleen M. Randolph, Nadim J. Ajami, Melinda Sheffield-Moore, William J. Durham, Melissa Morrison, Randall J. Urban, Traver J. Wright, Christopher J. Stewart, Jennifer R. Summons, Aaron L. Miller, Charan K Singh, Christopher P. Danesi, Richard B. Pyles, Lisa A. Kreber, E. Lichar Dillon
Publikováno v:
Journal of Neurotrauma. 37:1037-1051
Patients with chronic traumatic brain injury (TBI) requiring long-term, permanent care suffer a myriad of clinical symptoms (i.e., impaired cognition, fatigue, and other conditions) that persist for years beyond the acute brain injury. In addition to