Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Aaron L, Johnson"'
Publikováno v:
Retrovirology, Vol 15, Iss 1, Pp 1-22 (2018)
Abstract Background The HIV-1 accessory proteins Nef and Vpu alter cell surface levels of multiple host proteins to modify the immune response and increase viral persistence. Nef and Vpu can downregulate cell surface levels of the co-stimulatory mole
Externí odkaz:
https://doaj.org/article/a917ee133e8342659a66f3b944394e44
Autor:
Aaron L. Johnson, Brennan S. Dirk, Mathieu Coutu, S. M. Mansour Haeryfar, Eric J. Arts, Andrés Finzi, Jimmy D. Dikeakos
Publikováno v:
mSphere, Vol 1, Iss 6 (2016)
ABSTRACT Extensive genetic diversity is a defining characteristic of human immunodeficiency virus type 1 (HIV-1) and poses a significant barrier to the development of an effective vaccine. To better understand the impact of this genetic diversity on
Externí odkaz:
https://doaj.org/article/f2e1efd322d84669aeb8e11a593106fa
Autor:
Logan R. Van Nynatten, Aaron L. Johnson, Brennan S. Dirk, Emily N. Pawlak, Rajesh Abraham Jacob, S. M. Mansour Haeryfar, Jimmy D. Dikeakos
Publikováno v:
Viruses, Vol 10, Iss 9, p 493 (2018)
The human immunodeficiency virus type 1 (HIV-1) accessory protein Nef, plays an essential role in disease progression and pathogenesis via hijacking the host cellular membrane-trafficking machinery. Interestingly, HIV-1 group-M subtypes display diffe
Externí odkaz:
https://doaj.org/article/00e0777118c14d83b6a4fc8059add059
Autor:
Brennan S Dirk, Rajesh Abraham Jacob, Aaron L Johnson, Emily N Pawlak, P Craig Cavanagh, Logan Van Nynatten, S M Mansour Haeryfar, Jimmy D Dikeakos
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0125619 (2015)
The Human Immunodeficiency Virus type 1 (HIV-1) accessory protein Nef interacts with a multitude of cellular proteins, manipulating the host membrane trafficking machinery to evade immune surveillance. Nef interactions have been analyzed using variou
Externí odkaz:
https://doaj.org/article/4e674cd7cf0943a489f443bf3392ca5c
Autor:
Cassandra R Edgar, Jimmy D. Dikeakos, Steven M. Trothen, Aaron L. Johnson, Eric J. Arts, Mitchell J. Mumby, Peter B. Stathopulos, Richard M. Gibson
Publikováno v:
J Virol
Serine incorporator 5 (SERINC5) reduces the infectivity of progeny HIV-1 virions by incorporating into the outer host-derived viral membrane during egress. To counter SERINC5, the HIV-1 accessory protein Nef triggers SERINC5 internalization by engagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d88411f5351c4a5bb5b869a384350b
https://doi.org/10.1128/jvi.00588-21
https://doi.org/10.1128/jvi.00588-21
Autor:
Jimmy D. Dikeakos, Emily N. Pawlak, Rajesh Abraham Jacob, Brennan S. Dirk, S. M. Mansour Haeryfar, Logan R. Van Nynatten, Aaron L. Johnson
Publikováno v:
Virology. 509:1-10
Acquired Immune Deficiency Syndrome is characterized by a decline in CD4+ T cells. Here, we elucidated the mechanism underlying apoptosis in Human Immunodeficiency Virus-1 (HIV-1) infection by examining host apoptotic pathways hijacked by the HIV-1 N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92eae04630a1021cc7549a655049ff20
https://doi.org/10.1016/j.virol.2017.05.018
https://doi.org/10.1016/j.virol.2017.05.018
Autor:
Stefan Trapp, Rishi Anand, Ida J. Llewellyn-Smith, Aaron L. Johnson, J. Patrick Card, Daniel I. Brierley, Huiyuan Zheng, Linda Rinaman
Publikováno v:
The Journal of Comparative Neurology
Glutamatergic neurons that express pre‐proglucagon (PPG) and are immunopositive (+) for glucagon‐like peptide‐1 (i.e., GLP‐1+ neurons) are located within the caudal nucleus of the solitary tract (cNTS) and medullary reticular formation in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274b9caee9a0acb9ecede1f8446856e2
https://pubmed.ncbi.nlm.nih.gov/30019398
https://pubmed.ncbi.nlm.nih.gov/30019398
Publikováno v:
Retrovirology
Retrovirology, Vol 15, Iss 1, Pp 1-22 (2018)
Retrovirology, Vol 15, Iss 1, Pp 1-22 (2018)
Background The HIV-1 accessory proteins Nef and Vpu alter cell surface levels of multiple host proteins to modify the immune response and increase viral persistence. Nef and Vpu can downregulate cell surface levels of the co-stimulatory molecule CD28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53e6aa79acd8b4120042760a87216f
https://pubmed.ncbi.nlm.nih.gov/29329537
https://pubmed.ncbi.nlm.nih.gov/29329537
Autor:
Rajesh Abraham, Jacob, Aaron L, Johnson, Emily N, Pawlak, Brennan S, Dirk, Logan R, Van Nynatten, S M Mansour, Haeryfar, Jimmy D, Dikeakos
Publikováno v:
Virology. 509
Acquired Immune Deficiency Syndrome is characterized by a decline in CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5438b6efeacdc38a0e8ecf1f2a80e548
https://pubmed.ncbi.nlm.nih.gov/28577469
https://pubmed.ncbi.nlm.nih.gov/28577469
Autor:
Logan R. Van Nynatten, Rajesh Abraham Jacob, Bryan Heit, Brennan S. Dirk, Emily N. Pawlak, Jimmy D. Dikeakos, Aaron L. Johnson
Publikováno v:
Scientific Reports
A defining characteristic of HIV-1 infection is the ability of the virus to persist within the host. Specifically, MHC-I downregulation by the HIV-1 accessory protein Nef is of critical importance in preventing infected cells from cytotoxic T-cell me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53020546ba7e9bbbde185575ceadff71