Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aaron Koenig"'
Autor:
Ruta Sawant, Kyle Paret, Jennifer Petrillo, Aaron Koenig, Sorrel Wolowacz, Naoko Ronquest, Hugh Rickards
Publikováno v:
Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Huntington’s disease (HD) is a progressive neurodegenerative disease with a devastating impact on patients and their families. Quantifying how treatments affect patient outcomes is critical for informing reimbursement decisions.
Externí odkaz:
https://doaj.org/article/cd19fae1cda34df0b596e108f539e050
Autor:
Aaron Koenig, Michael Lewis, Jeff Wald, Sigui Li, Mustafa Varoglu, Jing Dai, Abdul Sankoh, Katrina Paumier, James Doherty, Mike Quirk
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 7, Pp n/a-n/a (2024)
Abstract N‐methyl‐D‐aspartate receptor (NMDAR)‐positive allosteric modulators (PAMs) represent a potential therapeutic strategy for cognitive impairment in disorders associated with NMDAR hypofunction, including Huntington's disease (HD) and
Externí odkaz:
https://doaj.org/article/39e2342313ec49e19d0b75707c08f91c
Autor:
Alan J. Lerner, Steven E. Arnold, Erin Maxfield, Aaron Koenig, Maria E. Toth, Brooke Fortin, Natalia Mast, Bianca A. Trombetta, John Denker, Andrew A. Pieper, Curtis Tatsuoka, Sangeetha Raghupathy, Irina A. Pikuleva
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Efavirenz is an anti-HIV drug, and cytochrome P450 46A1 (CYP46A1) is a CNS-specific enzyme that metabolizes cholesterol to 24-hydroxycholesterol (24HC). We have previously shown that allosteric CYP46A1 activation by low-dose efavi
Externí odkaz:
https://doaj.org/article/be51f0c921904c6eb9b8ba7aa6a50ed7
Autor:
Tiffany Lago, Aaron Koenig, Jason Johannesen, Sola Park, Sigui Li, Emily Freitag, Jeffrey Wald, Katrina Paumier, Michael Quirk, James Doherty
Publikováno v:
Tuesday, April 25.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48e81e435e61743e665d1e90a460f488
https://doi.org/10.1212/wnl.0000000000203929
https://doi.org/10.1212/wnl.0000000000203929
Autor:
Amy Bullock, Aaron Koenig, Katrina Paumier, Emily Freitag, Jeffrey Wald, Sola Park, Michael Quirk, Jennifer Petrillo Billet, James Doherty
Publikováno v:
Sunday, April 23.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dd0386843d77f046a1c8301b260de61
https://doi.org/10.1212/wnl.0000000000203649
https://doi.org/10.1212/wnl.0000000000203649
Autor:
Aaron Koenig, Shishuka Malhotra, Jeffrey Wald, Jennifer Petrillo, Katrina Paumier, Jason Johannensen, Sigui Li, Michael Quirk, Emily Freitag, Jim Doherty
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db0cf2c8a22dc50cbfa5fcb7e90d0ada
https://doi.org/10.1002/alz.063896
https://doi.org/10.1002/alz.063896
Autor:
Jennifer Petrillo, Kyle Paret, Ruta Sawant, Aaron Koenig, Sorrel Wolowacz, Naoko Ronquest, Hugh Rickards
Publikováno v:
F: Clinical studies: case reports, observational studies and trials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33a51ce85611d99a812f82c4e06b1d34
https://doi.org/10.1136/jnnp-2022-ehdn.118
https://doi.org/10.1136/jnnp-2022-ehdn.118
Autor:
Aaron Koenig, Julie Stout, Jason Johannesen, Jennifer Petrillo, Sigui Li, Pranoti Pradhan, Emily Lefler, Katrina Paumier, Jeffrey Wald, Mike Quirk, James Doherty
Publikováno v:
J: Clinical therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e16f1d99cb357486fe8539c39a15ce3f
https://doi.org/10.1136/jnnp-2022-ehdn.262
https://doi.org/10.1136/jnnp-2022-ehdn.262
Autor:
Alan J. Lerner, Steven E. Arnold, Erin Maxfield, Aaron Koenig, Maria E. Toth, Brooke Fortin, Natalia Mast, Bianca A. Trombetta, John Denker, Andrew A. Pieper, Curtis Tatsuoka, Sangeetha Raghupathy, Irina A. Pikuleva
Background: Efavirenz is an anti-HIV drug, and cytochrome P450 46A1 (CYP46A1) is a CNS-specific enzyme that metabolizes cholesterol to 24-hydroxycholesterol (24HC). We have previously shown that allosteric CYP46A1 activation by low-dose efavirenz in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26ea50c83440c7aa8ab697533a08bd1
https://doi.org/10.21203/rs.3.rs-1348328/v1
https://doi.org/10.21203/rs.3.rs-1348328/v1
Autor:
Maria Stepanova, Stephen Clement, Shirley Kalwaney, Zobair M. Younossi, Sean Felix, Aaron Koenig
Publikováno v:
Liver International. 36:1096-1100
BACKGROUND & AIMS Given the severity of acute hepatitis in patients with chronic liver diseases (CLD) and patients with type 2 diabetes (DM), most of these patients are recommended to be vaccinated. The aim is to assess the recent changes in HAV and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea1f46f9d6ae1907de8a60c2d1cb978
https://doi.org/10.1111/liv.13164
https://doi.org/10.1111/liv.13164