Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Aaron K.F. Wong"'
Autor:
Calum Forteath, Ify Mordi, Raid Nisr, Erika J. Gutierrez-Lara, Noor Alqurashi, Iain R. Phair, Amy R. Cameron, Craig Beall, Ibrahim Bahr, Mohapradeep Mohan, Aaron K.F. Wong, Adel Dihoum, Anwar Mohammad, Colin N.A. Palmer, Douglas Lamont, Kei Sakamoto, Benoit Viollet, Marc Foretz, Chim C. Lang, Graham Rena
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101750- (2023)
Objective: Unexplained changes in regulation of branched chain amino acids (BCAA) during diabetes therapy with metformin have been known for years. Here we have investigated mechanisms underlying this effect. Methods: We used cellular approaches, inc
Externí odkaz:
https://doaj.org/article/6034f1d72e63418cb69e689338644a8d
The effect of metformin on insulin resistance and exercise parameters in patients with heart failure
Autor:
Anna Maria Choy, Aaron K.F. Wong, Simon Ogston, John R. Petrie, Matlooba A. AlZadjali, Donald S.C. Ang, Chim C. Lang, R. Symon, Allan D. Struthers
Publikováno v:
European Journal of Heart Failure. 14:1303-1310
Aims Chronic heart failure (CHF) is an insulin-resistant state. The degree of insulin resistance (IR) correlates with disease severity and is associated with reduced exercise capacity. In this proof of concept study, we have examined the effect of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea04f71c8539dd28d62714fb9a11991
https://doi.org/10.1093/eurjhf/hfs106
https://doi.org/10.1093/eurjhf/hfs106
Publikováno v:
Heart Failure Clinics. 8:539-550
Chronic heart failure (CHF) is an insulin-resistant (IR) state and the degree of IR is related to disease severity and poor clinical outcome in CHF. IR may be pathophysiologically linked with CHF. Therefore, IR may represent a new target for treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b515631139c0361fda3b49a7c3b5dc0
https://doi.org/10.1016/j.hfc.2012.06.002
https://doi.org/10.1016/j.hfc.2012.06.002
Autor:
Simon Ogston, John R. Petrie, Alex S. F. Doney, Josie M M Evans, Aaron K.F. Wong, Andrew D. Morris, Chim C. Lang, Matlooba A. AlZadjali, Allan D. Struthers
Publikováno v:
The American Journal of Cardiology. 106:1006-1010
Type 2 diabetes mellitus (DM) plus chronic heart failure (CHF) is a common but lethal combination and therapeutic options are limited. Metformin is perceived as being relatively contraindicated in this context, although mounting evidence indicates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845aa8475677725ddc8fa23e5feae994
https://doi.org/10.1016/j.amjcard.2010.05.031
https://doi.org/10.1016/j.amjcard.2010.05.031
Autor:
Allan D. Struthers, Anna Maria Choy, R. S. Symon, D. S. C. Ang, John R. Petrie, Chim C. Lang, Matlooba A. AlZadjali, Aaron K.F. Wong
Publikováno v:
European Heart Journal. 31:589-871
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2a195e8e795b89185094b0b060dadf
https://doi.org/10.1093/eurheartj/ehq289
https://doi.org/10.1093/eurheartj/ehq289
Publikováno v:
Clinical Science (London, England : 1979)
AMPK (AMP-activated protein kinase) is a heterotrimetric enzyme that is expressed in many tissues, including the heart and vasculature, and plays a central role in the regulation of energy homoeostasis. It is activated in response to stresses that le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70a1d402ca71be397789affe0feaacb
http://europepmc.org/articles/PMC2762688
http://europepmc.org/articles/PMC2762688
Autor:
Tian-Hai Koh, Aaron K.F. Wong, Kean-Wah Lau, Charles Chan, Lai-Heng Lee, Koon-Hou Mak, Yean-Leng Lim
Publikováno v:
The American Journal of Cardiology. 89:930-936
The purpose of this study was to determine the impact of these 2 reperfusion strategies (reduced-dose alteplase plus abciximab or direct angioplasty plus abciximab) on fibrinolytic and thrombin generation activities. The effect of reduced-dose altepl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef294ef893a2660ebdbd5078d3eb8b2b
https://doi.org/10.1016/s0002-9149(02)02241-5
https://doi.org/10.1016/s0002-9149(02)02241-5
Publikováno v:
A Practical Guide to Heart Failure in Older People
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c84c71a92afdc0f143a16dd846a6358
https://doi.org/10.1002/9780470742945.ch11
https://doi.org/10.1002/9780470742945.ch11
Publikováno v:
Cardiovascular therapeutics. 26(3)
There is increasing evidence to suggest that chronic heart failure (CHF) is an insulin resistant (IR) state and that the degree of IR correlates with the severity and mortality of CHF. The pathophysiology of IR in CHF has yet to be fully defined. Add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2264513475c014889aef721e8c17ae90
https://pubmed.ncbi.nlm.nih.gov/18786090
https://pubmed.ncbi.nlm.nih.gov/18786090
Publikováno v:
Case Studies in Interventional Cardiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08eca2ac46052b639b46022461eec803
https://doi.org/10.1201/b14293-44
https://doi.org/10.1201/b14293-44