Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aaron J. Senior"'
Autor:
Liam T. Ball, Aaron J. Senior
Publikováno v:
Synlett. 32:235-240
We recently reported a general and practical strategy for the Bi(V)-mediated C–H arylation of phenols and naphthols. Our telescoped protocol proceeds via transmetallation from readily available arylboronic acids to a stable Bi(III) precursor, oxida
Autor:
Harley Green, Lydia Barnes, Jolyon Matthews-Wright, Rachel Szpara, Luke Francis, Nuria S. Lima, Hollie Blaber, Carrie K. W. Wong, Alexander Seal, Charlotte S. Payne, Matthew F. Meehan, C. Elizabeth Killalea, Rohan J. Trainor, Katherine Wood, Jack M. J. Grace, Oliver Williams, Liam Cochrane, Edmund J. P. Hogarth, Katherine Louise Jones, Zoe J. Lee, Shusha Mahdy, Anna Gruszka, Lisa Morrison, Freya Taday, Leyla Jusu, Oliver King, May-Li Mackinnon, Joe Stillibrand, Daniel Buckley, Edward Cooney, Z.A. Henley, Simon J. F. Macdonald, Christina L. Long, Daniel Fu He, Craig Pike, Zoe C. Byron, Keenan M. Smith, Ian Edward David Smith, Antony M. Threadgould, Lewis Byers, Kamile Stanelyte, Hal R. I. Parke, Nick Barton, Rosa Cookson, James E. Rowedder, Andrew Nortcliffe, Aaron J. Senior, Alan Nadin, Makenzie J. Millward, Joseph Lambert, Lawrence Payne, David T. K. Brooks, Christopher Merrett, Heather A. Damian, Jordan Waters, Richard G. Chilvers
Publikováno v:
Journal of Medicinal Chemistry. 62:10402-10422
Phosphoinositide-3-kinase δ (PI3Kδ) is a critical regulator of cell growth and transformation and has been explored as a therapeutic target for a range of diseases. Through the exploration of the t...
Autor:
Lydia, Barnes, Hollie, Blaber, David T K, Brooks, Lewis, Byers, Daniel, Buckley, Zoe C, Byron, Richard G, Chilvers, Liam, Cochrane, Edward, Cooney, Heather A, Damian, Luke, Francis, Daniel, Fu He, Jack M J, Grace, Harley J, Green, Edmund J P, Hogarth, Leyla, Jusu, C Elizabeth, Killalea, Oliver, King, Joseph, Lambert, Zoe J, Lee, Nuria S, Lima, Christina L, Long, May-Li, Mackinnon, Shusha, Mahdy, Jolyon, Matthews-Wright, Makenzie J, Millward, Matthew F, Meehan, Christopher, Merrett, Lisa, Morrison, Hal R I, Parke, Charlotte, Payne, Lawrence, Payne, Craig, Pike, Alexander, Seal, Aaron J, Senior, Keenan M, Smith, Kamile, Stanelyte, Joe, Stillibrand, Rachel, Szpara, Freya F H, Taday, Antony M, Threadgould, Rohan J, Trainor, Jordan, Waters, Oliver, Williams, Carrie K W, Wong, Katherine, Wood, Nick, Barton, Anna, Gruszka, Zoe, Henley, James E, Rowedder, Rosa, Cookson, Katherine L, Jones, Alan, Nadin, Ian E, Smith, Simon J F, Macdonald, Andrew, Nortcliffe
Publikováno v:
Journal of medicinal chemistry. 62(22)
Phosphoinositide-3-kinase δ (PI3Kδ) is a critical regulator of cell growth and transformation and has been explored as a therapeutic target for a range of diseases. Through the exploration of the thienopyrimidine scaffold, we have identified a liga