Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Aaron J. Reynolds"'
Publikováno v:
Frontiers in Nuclear Engineering, Vol 2 (2023)
The detailed behavior of neutrons in a rapidly changing time-dependent physical system is a challenging computational physics problem, particularly when using Monte Carlo methods on heterogeneous high-performance computing architectures. A small numb
Externí odkaz:
https://doaj.org/article/03667652a0574b66aa8053870c62a696
Autor:
Aaron J. Reynolds, Todd S. Palmer
Publikováno v:
Nuclear Science and Engineering. 197:45-73
Autor:
Aaron J. Reynolds, Kenneth R. Leopold
Publikováno v:
Journal of Molecular Spectroscopy. 394:111787
Autor:
John C. Conboy, Aaron J. Reynolds
Publikováno v:
Sensors and Actuators B: Chemical. 273:921-926
A second harmonic generation humidity sensor was constructed with a sensing layer composed of cubic phase barium titanate nanoparticles. The sensor shows a linear response up to a relative humidity of 80%, with response times of 40 ± 10 s for decrea
Publikováno v:
British Journal of Pharmacology. 167:1076-1088
BACKGROUND AND PURPOSE N-arachidonoyl 5-HT (NA-5HT) has anti-nociceptive effects reported to be mediated by inhibitory actions at the transient receptor potential vanilloid receptor 1 (TRPV1) and fatty acid amide hydrolase (FAAH). Anandamide and N-ar
Autor:
Shane M. Wilkinson, Samuel D. Banister, Michael Kassiou, Aaron J. Reynolds, David E. Hibbs, Raphy Hanani
Publikováno v:
Tetrahedron Letters. 53:3780-3783
A practical, multigram approach to the 2-(2-(4-alkoxyphenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide (DPA) class of ligands targeting the translocator protein (TSPO) is described. This synthetic route offers several improvements over all
Autor:
Clovis Tauber, Aaron J. Reynolds, Michael Kassiou, Maria-Joao Ribeiro, Jean-Louis Baulieu, Philippe Corcia, Johnny Vercouillie, Denis Guilloteau, Michael G. Stabin, Y. Venel, S. Maia, Nicolas Arlicot
Publikováno v:
Nuclear Medicine and Biology. 39:570-578
Introduction The translocator protein 18 kDa (TSPO), although minimally expressed in healthy brain, is up-regulated in pathological conditions, coinciding with microglial activation. It is thereby a suitable in vivo biomarker of neuroinflammation for
Autor:
Sylvie Bodard, Michael Kassiou, Katherine R. Leaver, Sylvie Chalon, Denis Guilloteau, Aaron J. Reynolds
Publikováno v:
ACS Chemical Neuroscience. 3:114-119
There is evidence that excitotoxicity and prolonged microglial activation are involved in neuronal death in neurodegenerative disorders. Activated microglia express various molecules, including the translocator protein 18 kDa (TSPO; formerly known as
Autor:
Matthew J. McDonough, Stephen J. Butler, Katrina A. Jolliffe, Wee Yu Gladys Lee, Aaron J. Reynolds
Publikováno v:
Tetrahedron. 67:1019-1029
Three analogues of the Lissoclinum class of cyclic peptides, bearing dipicolylamino functionalised side chains, have been synthesised using a stepwise approach followed by macrocyclisation. Attempts to incorporate dipicolylamino functionalised side c
Autor:
Aaron J. Reynolds, Iman A. Moussa, Samuel D. Banister, William T. Jorgensen, Corinne Beinat, Paolo Schiavini, Michael Kassiou
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:38-41
In our continued exploration of trishomocubane derivatives with central nervous system (CNS) activity, N -arylalkyl-8-aminopentacyclo[5.4.0.0 2,6 .0 3,10 .0 5,9 ]undecanes ( 10 – 13 ) displaying affinity for the sigma (σ) receptor were also found,