Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Aaron J Polichnowski"'
Autor:
Jacqueline C. Potter, Shannon A. Whiles, Conor B. Miles, Jenna B. Whiles, Mark A. Mitchell, Brianna E. Biederman, Febronia M. Dawoud, Kevin F. Breuel, Geoffrey A. Williamson, Maria M. Picken, Aaron J. Polichnowski
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 21 (2021)
Background Abnormal renal hemodynamic responses to salt‐loading are thought to contribute to salt‐sensitive (SS) hypertension. However, this is based largely on studies in anesthetized animals, and little data are available in conscious SS and sa
Externí odkaz:
https://doaj.org/article/95e73596ef0c401aade64fc2a802e26c
Autor:
Trevin C Wilkes, Jingping Sun, Christina L Sartain, Aaron J. Polichnowski, Paul M. O'Connor, Elinor C. Mannon
Publikováno v:
Am J Physiol Renal Physiol
Impairments in insulin sensitivity can occur in patients with chronic kidney disease (CKD). Correction of metabolic acidosis has been associated with improved insulin sensitivity in CKD, suggesting that metabolic acidosis may directly promote insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815c745e11c320ca7fb0ad6a8897328d
https://doi.org/10.1152/ajprenal.00679.2020
https://doi.org/10.1152/ajprenal.00679.2020
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
Donepezil is a centrally acting acetylcholinesterase (AChE) inhibitor with therapeutic potential in inflammatory diseases; however, the underlying autonomic and cholinergic mechanisms remain unclear. Here, we assessed effects of donepezil on mean art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ddff1657d063446a191f443437def3
https://doi.org/10.1152/ajpregu.00360.2019
https://doi.org/10.1152/ajpregu.00360.2019
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f11313f480f97ef23141df4612dc409
https://doi.org/10.1096/fasebj.2022.36.s1.r4990
https://doi.org/10.1096/fasebj.2022.36.s1.r4990
Autor:
Paul M. O'Connor, Bansari Patel, Sarah C. Ray, Qingqing Wei, Jingping Sun, G. Ryan Crislip, Aaron J. Polichnowski, Jennifer C. Sullivan, Riyaz Mohamed
Publikováno v:
Am J Physiol Renal Physiol
Noninvasive determination of the severity of parenchymal injury in acute kidney injury remains challenging. Edema is an early pathological process following injury, which may correlate with changes in kidney volume. The goal of the present study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c88e74cd603cb1a286d45d9ea2d0403
https://doi.org/10.1152/ajprenal.00221.2020
https://doi.org/10.1152/ajprenal.00221.2020
Autor:
Brianna E Biederman, Shannon A Whiles, Conor B Miles, Aaron J Polichnowski, Jacqueline C Potter, Jenna B Whiles, Geoffrey A. Williamson, Maria M. Picken, Kevin F Breuel, Mark A Mitchell, Febronia M Dawoud
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 21 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Abnormal renal hemodynamic responses to salt‐loading are thought to contribute to salt‐sensitive (SS) hypertension. However, this is based largely on studies in anesthetized animals, and little data are available in conscious SS and sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e282db3ef753230e999163574b96740f
https://www.ahajournals.org/doi/10.1161/JAHA.120.020261
https://www.ahajournals.org/doi/10.1161/JAHA.120.020261
Autor:
Aaron J. Polichnowski
Publikováno v:
American Journal of Physiology-Renal Physiology. 315:F1513-F1518
Acute kidney injury (AKI) is a major complication in hospitalized patients and is associated with elevated mortality rates. Numerous recent studies indicate that AKI also significantly increases the risk of chronic kidney disease (CKD), end-stage ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b777eb440635100ef8f6f55e5f69522a
https://doi.org/10.1152/ajprenal.00419.2018
https://doi.org/10.1152/ajprenal.00419.2018
Autor:
Aaron J. Polichnowski, Karen A. Griffin, Geoffrey A. Williamson, Anil K. Bidani, Sebastian Alphonse
Publikováno v:
EUSIPCO
A convolutional deep neural network is employed to assess renal autoregulation using time series of arterial blood pressure and blood flow rate measurements in conscious rats. The network is trained using representative data samples from rats with in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3201cc419cab88cd611bf741d8fad331
https://doi.org/10.23919/eusipco47968.2020.9287447
https://doi.org/10.23919/eusipco47968.2020.9287447
Autor:
Susanne Mathia, Aaron J. Polichnowski, Manjeri A. Venkatachalam, Anil K. Bidani, Karen A. Griffin, Jainrui Long, Geoffrey A. Williamson, Maria M. Picken, Rongpei Lan, Christian Rosenberger, Hector Licea-Vargas
Publikováno v:
Am J Physiol Renal Physiol
Unilateral ischemia-reperfusion (UIR) injury leads to progressive renal atrophy and tubulointerstitial fibrosis (TIF) and is commonly used to investigate the pathogenesis of the acute kidney injury-chronic kidney disease transition. Although it is we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8085492c9e43c2497857a83266bc7116
https://europepmc.org/articles/PMC7294334/
https://europepmc.org/articles/PMC7294334/
Autor:
Jianrui Long, Karen A. Griffin, Anil K. Bidani, Aaron J. Polichnowski, Geoffrey A. Williamson, Stephanie Kliethermes, Hector Licea-Vargas
Publikováno v:
J Am Soc Nephrol
Background Renal autoregulation maintains stable renal function despite BP fluctuations and protects glomerular capillaries from hypertensive injury. However, real-time dynamics of renal autoregulation in conscious animals have not been characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4175fa1ce3ec2b0952e1e4fd710ffb
https://pubmed.ncbi.nlm.nih.gov/31792155
https://pubmed.ncbi.nlm.nih.gov/31792155