Impaired top-down auditory processing despite extensive single-neuron responses during human sleep

Autor: Firas Fahoum, Yaniv Sela, Aaron J Krom, Ido Strauss, Yuval Nir, Ariel Tankus, Hanna Hayat, Amit Marmelshtein, Itzhak Fried

Sleep in all species is universally defined as a reversible, homeostatically-regulated state of a reduced behavioral responsiveness, with a high arousal threshold in response to external sensory stimulation1. However, it remains unclear whether sleep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a52afe32729044034ffc4afafce4729e
https://doi.org/10.1101/2021.04.03.438283

Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep

Autor: Marina Lavigne, Yuval Nir, Ofer Yizhar, Aaron J Krom, Yong Li, Elena Paredes-Rodriguez, Hanna Hayat, Eric J. Kremer, Anna C Sales, Anthony E. Pickering, Noa Matosevich, Lottem Bergman, Noa Regev

Publikováno v: Science Advances
Addi. Archivo Digital para la Docencia y la Investigación
instname
Hayat, H, Regev, N, Matosevich, N, Sales, A C, Paredes, E, Krom, A, Bergman, L, Li, Y, Lavigne, M, Kremer, E J, Yizhar, O, Pickering, A E & Nir, Y 2020, ' Locus coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep ', Science Advances, vol. 6, no. 15, eaaz4232 . https://doi.org/10.1126/sciadv.aaz4232

Do noises wake you up at night? Blame your locus coeruleus.
A defining feature of sleep is reduced responsiveness to external stimuli, but the mechanisms mediating sensory-evoked arousal remain unclear. We hypothesized that reduced locus coerule

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2cbe1ffdd807c70f390f0509c341ac
https://doi.org/10.1126/sciadv.aaz4232

Locus-coeruleus norepinephrine activity gates sensory-evoked awakenings from sleep

Autor: Ofer Yizhar, Lottem Bergman, Noa Regev, Aaron J Krom, Noa Matosevich, Yuval Nir, Anna C Sales, Marina Lavigne, Eric J. Kremer, Elena Paredes-Rodriguez, Anthony E. Pickering, Yong Li, Hanna Hayat

A defining feature of sleep is reduced responsiveness to external stimuli, but the mechanisms gating sensory-evoked arousal remain unclear. We hypothesized that reduced locus-coeruleus norepinephrine (LC-NE) activity during sleep mediates unresponsiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674ff28f8b0705b52bd7643f3735f9a5

Anesthesia-induced loss of consciousness disrupts auditory responses beyond primary cortex

Autor: Hagar Gelbard-Sagiv, Aaron J Krom, Firas Fahoum, Florian Mormann, Itzhak Fried, Ariel Tankus, Daniel Hayat, Idit Matot, Jan Boström, Hanna Hayat, Ido Strauss, Yuval Nir, Amit Marmelshtein, Martin Soehle

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 21

Despite its ubiquitous use in medicine, and extensive knowledge of its molecular and cellular effects, how anesthesia induces loss of consciousness (LOC) and affects sensory processing remains poorly understood. Specifically, it is unclear whether an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bbcb5d5e810e54563e81e9f1631611
https://doi.org/10.1101/502385

Evaluation of image enhancement software as a method of performing half-count bone scans

Autor: Aaron J Krom, Daniel McCool, Maria Burniston, Margaret L. Hall, Shaunak Navalkissoor, Fred Wickham

Publikováno v: Nuclear Medicine Communications. 34:78-85

Reducing the radiation dose and scanning time of diagnostic tests is often desirable. One method uses image enhancement software such as Pixon, which processes lower-count scans and aims to produce high-quality images. However, it is essential that d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9727e5b03c18717f59aff22386832e3
https://doi.org/10.1097/mnm.0b013e32835afb45