Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Aaron J, Marshall"'
Autor:
Jiayu Yang, Lin Yang, Bryan Tordon, Oliver Bucher, Zoann Nugent, Ivan Landego, Nicole Bourrier, Kelsey Uminski, Kevin Brown, Mandy Squires, Aaron J. Marshall, Sachin Katyal, Salah Mahmud, Kathleen Decker, Marc Geirnaert, David E. Dawe, Spencer B. Gibson, James B. Johnston, Versha Banerji
Publikováno v:
Current Oncology, Vol 30, Iss 7, Pp 6411-6431 (2023)
FISH cytogenetics, TP53 sequencing, and IGHV mutational status are increasingly used as prognostic and predictive markers in chronic lymphocytic leukemia (CLL), particularly as components of the CLL International Prognostic Index (CLL-IPI) and in dir
Externí odkaz:
https://doaj.org/article/7bad489516bf4cf980412144ad8710cb
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Phosphoinositide 3-kinase delta (PI3Kδ) plays key roles in normal B cell activation and is chronically activated in malignant B cells. Targeting of PI3Kδ using FDA-approved drugs Idelalisib or Umbralisib has shown efficacy in treatment of multiple
Externí odkaz:
https://doaj.org/article/3b37015d9e6b4e7fab38378cc6ddab3c
Autor:
Vidyanand Anaparti, Stacy Tanner, Christine Zhang, Liam O’Neil, Irene Smolik, Xiaobo Meng, Aaron J. Marshall, Hani El-Gabalawy
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDespite immune cell dysregulation being an important event preceding the onset of rheumatoid arthritis (RA), the phenotype of T and B cells in preclinical RA is less understood. The aim of this study was to characterize T and B cell populat
Externí odkaz:
https://doaj.org/article/9e3c744dcbd940bfa44b14a77c894054
Autor:
Sumanta Chatterjee, Vasudeva Bhat, Alexei Berdnikov, Jiahui Liu, Guihua Zhang, Edward Buchel, Janice Safneck, Aaron J. Marshall, Leigh C. Murphy, Lynne-Marie Postovit, Afshin Raouf
Publikováno v:
iScience, Vol 19, Iss , Pp 388-401 (2019)
Summary: Breast cancer-induced activated fibroblasts support tumor progression. However, the role of normal fibroblasts in tumor progression remains controversial. In this study, we used modified patient-derived organoid cultures and demonstrate that
Externí odkaz:
https://doaj.org/article/e2ec1c1892864a9d9d4ce305d8e93e07
Autor:
Ganchimeg Ishdorj, Erin Streu, Pascal Lambert, Harbhajan S. Dhaliwal, Salaheddin M. Mahmud, Spencer B. Gibson, Versha Banerji, Aaron J. Marshall, James B. Johnston
Publikováno v:
Blood Advances, Vol 3, Iss 14, Pp 2188-2198 (2019)
Abstract: To better understand the relationship between baseline immunoglobulin measurements and subsequent clinical outcomes in chronic lymphocytic leukemia (CLL), we performed a retrospective analysis on 660 patients with CLL (72%), monoclonal B-ce
Externí odkaz:
https://doaj.org/article/f4af79f0a169496b81de1bc4850778c0
Autor:
Xun Wu, J. Ernesto Fajardo-Despaigne, Christine Zhang, Vishala Neppalli, Versha Banerji, James B. Johnston, Spencer B. Gibson, Aaron J. Marshall
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Follicular helper T cells (TFH) have specialized properties in promoting normal B cell activation but their role in chronic lymphocytic leukemia (CLL) is unknown. We find that TFH cells are elevated in CLL patients and are phenotypically abnormal, ex
Externí odkaz:
https://doaj.org/article/827fadeeeb294773acded8a7e74c18c2
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/e0f04de1be9540768fbf54512a64a457
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
B cell adaptor molecule of 32 kDa (Bam32), known as dual adapter for phosphotyrosine and 3-phosphoinositides 1 (DAPP1), has been implicated in regulating lymphocyte proliferation and recruitment during inflammation. However, its role in neutrophils d
Externí odkaz:
https://doaj.org/article/a7507e371c9d48cb9f798da29f7416f8
Autor:
Hana M. Zegallai, Ejlal Abu-El-Rub, Edgard M. Mejia, Genevieve C. Sparagna, Laura K. Cole, Aaron J. Marshall, Grant M. Hatch
Publikováno v:
Cell and Tissue Research. 390:429-439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66e3731ea97ed0967723d64c130f7f5d
https://doi.org/10.1007/s00441-022-03692-z
https://doi.org/10.1007/s00441-022-03692-z
Autor:
Banerji, Jiayu Yang, Lin Yang, Bryan Tordon, Oliver Bucher, Zoann Nugent, Ivan Landego, Nicole Bourrier, Kelsey Uminski, Kevin Brown, Mandy Squires, Aaron J. Marshall, Sachin Katyal, Salah Mahmud, Kathleen Decker, Marc Geirnaert, David E. Dawe, Spencer B. Gibson, James B. Johnston, Versha
Publikováno v:
Current Oncology; Volume 30; Issue 7; Pages: 6411-6431
FISH cytogenetics, TP53 sequencing, and IGHV mutational status are increasingly used as prognostic and predictive markers in chronic lymphocytic leukemia (CLL), particularly as components of the CLL International Prognostic Index (CLL-IPI) and in dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::292dc06760abebbf71721f52839bdecb