Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aaron J, Hsueh"'
Autor:
Aaron J. Hsueh
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 04, Pp 239-239 (2023)
Darwin’s evolution theory serves as the basis to understand biology and medicine. In addition to fossil evidence used by Darwin and his contemporaries, advances in genomics allowed the tracing of gene sequences. Understanding human evolution furthe
Externí odkaz:
https://doaj.org/article/6153d0e22a4c40ec950395b5195bc979
Autor:
Aaron J. Hsueh
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 04, Pp 231-231 (2023)
All human genes have undergone hundreds of millions of years of evolution to have today’s sequences and associated functions. At the same time, ligands and receptors have also undergone co-evolution. Evolutionary methods can be used to find ligands
Externí odkaz:
https://doaj.org/article/95f9c1d12e5e43d491be3f79382211f1
Publikováno v:
Journal of minimally invasive gynecology. 29(7)
Recent findings have shown mechanical fragmentation of ovarian cortex and ovarian drilling could promote follicle growth in patients with premature ovarian insufficiency and polycystic ovarian syndrome, respectively. A common element shared by these
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117769 (2015)
Mammalian target of rapamycin (mTOR) is a serine/threonine kinase and mTOR signaling is important in regulating cell growth and proliferation. Recent studies using oocyte- and granulosa cell-specific deletion of mTOR inhibitor genes TSC1 or TSC2 demo
Externí odkaz:
https://doaj.org/article/234631f4440945f78c12c3a5822d8b6f
Autor:
Qingling, Yang, Luping, Cong, Yujiao, Wang, Xiaoyan, Luo, Hui, Li, Huan, Wang, Jing, Zhu, Shanjun, Dai, Haixia, Jin, Guidong, Yao, Senlin, Shi, Aaron J, Hsueh, Yingpu, Sun
Publikováno v:
Free radical biologymedicine. 156
Loss of follicles together with decreased oocyte quality and quantity contribute to age-associated ovarian senescence and infertility. Although underlying mechanisms for ovarian senescence are still unknown, mitochondrial dysfunctions have been repor
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30649 (2012)
It is important to identify effective contraceptive drugs that cause minimal disruption to physiological processes. Phosphodiesterase 3 (PDE3) inhibitors suppress meiosis in oocytes by decreasing the level of cAMP and blocking the extrusion of the fi
Externí odkaz:
https://doaj.org/article/821c37a532844faf9ef9c7f45865b4ba
Autor:
Sohyun L McElroy, James A Byrne, Shawn L Chavez, Barry Behr, Aaron J Hsueh, Lynn M Westphal, Renee A Reijo Pera
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10979 (2010)
BACKGROUND: Approximately 20% of oocytes are classified as immature and discarded following intracytoplasmic sperm injection (ICSI) procedures. These oocytes are obtained from gonadotropin-stimulated patients, and are routinely removed from the cumul
Externí odkaz:
https://doaj.org/article/978757e6b3f74c9d83055c3603d77bc0
Autor:
Kelley S, Yan, Claudia Y, Janda, Junlei, Chang, Grace X Y, Zheng, Kathryn A, Larkin, Vincent C, Luca, Luis A, Chia, Amanda T, Mah, Arnold, Han, Jessica M, Terry, Akifumi, Ootani, Kelly, Roelf, Mark, Lee, Jenny, Yuan, Xiao, Li, Christopher R, Bolen, Julie, Wilhelmy, Paige S, Davies, Hiroo, Ueno, Richard J, von Furstenberg, Phillip, Belgrader, Solongo B, Ziraldo, Heather, Ordonez, Susan J, Henning, Melissa H, Wong, Michael P, Snyder, Irving L, Weissman, Aaron J, Hsueh, Tarjei S, Mikkelsen, K Christopher, Garcia, Calvin J, Kuo
Publikováno v:
Nature. 545(7653)
The canonical Wnt/β-catenin signalling pathway governs diverse developmental, homeostatic and pathological processes. Palmitoylated Wnt ligands engage cell-surface frizzled (FZD) receptors and LRP5 and LRP6 co-receptors, enabling β-catenin nuclear
Autor:
Erik A H, Knauff, Lude, Franke, Michael A, van Es, Leonard H, van den Berg, Yvonne T, van der Schouw, Joop S E, Laven, Cornelius B, Lambalk, Annemieke, Hoek, Angelique J, Goverde, Sophie, Christin-Maitre, Aaron J, Hsueh, Cisca, Wijmenga, Bart C J M, Fauser, B J, Cohlen
Publikováno v:
Human Reproduction, 24(9), 2372-2378. Oxford University Press
Human reproduction (Oxford, England), 24(9), 2372-2378. Oxford University Press
Knauff, E A H, Franke, L, Es, M A, Van den Berg, L H, van der Schouw, Y T, Laven, J S E, Lambalk, C B, Hoek, A, Goverde, A J, Christin-Maitre, S, Hsueh, A J, Wijmenga, C & Fauser, B C J M 2009, ' Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene ', Human Reproduction, vol. 24, no. 9, pp. 2372-2378 . https://doi.org/10.1093/humrep/dep197
Human Reproduction, 24, 9, pp. 2372-8
Human reproduction (Oxford, England), 24(9), 2372-2378. Oxford University Press
Knauff, E A H, Franke, L, Es, M A, Van den Berg, L H, van der Schouw, Y T, Laven, J S E, Lambalk, C B, Hoek, A, Goverde, A J, Christin-Maitre, S, Hsueh, A J, Wijmenga, C & Fauser, B C J M 2009, ' Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene ', Human Reproduction, vol. 24, no. 9, pp. 2372-2378 . https://doi.org/10.1093/humrep/dep197
Human Reproduction, 24, 9, pp. 2372-8
Contains fulltext : 80633.pdf (Publisher’s version ) (Closed access) BACKGROUND: Spontaneous premature ovarian failure (POF) occurs in 1% of women and has major implications for their fertility and health. Besides X chromosomal aberrations and frag
Autor:
Leon J, Spicer, Pauline Y, Aad, Dustin T, Allen, Sabine, Mazerbourg, Anita H, Payne, Aaron J, Hsueh
Publikováno v:
Biology of reproduction. 78(2)
Ovarian follicular development is controlled by numerous paracrine and endocrine regulators, including oocyte-derived growth differentiation factor 9 (GDF9), and a localized increase in bioavailable insulin-like growth factor 1 (IGF1). The effects of