Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Aaron Hechmer"'
Autor:
Rex H. Lee, Ritu Roy, Hua Li, Aaron Hechmer, Tian Ran Zhu, Adila Izgutdina, Adam B. Olshen, Daniel E. Johnson, Jennifer R. Grandis
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
There are currently no clinical strategies utilizing tumor gene expression to inform therapeutic selection for patients with head and neck squamous cell carcinoma (HNSCC). One of the challenges in developing predictive biomarkers is the limited chara
Externí odkaz:
https://doaj.org/article/fa000583673044f0affae32431c0d9cc
Autor:
Mehdi Bouhaddou, Rex H. Lee, Hua Li, Neil E. Bhola, Rachel A. O’Keefe, Mohammad Naser, Tian Ran Zhu, Kelechi Nwachuku, Umamaheswar Duvvuri, Adam B. Olshen, Ritu Roy, Aaron Hechmer, Jennifer Bolen, Stephen B. Keysar, Antonio Jimeno, Gordon B. Mills, Scott Vandenberg, Danielle L. Swaney, Daniel E. Johnson, Nevan J. Krogan, Jennifer R. Grandis
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
The epidermal growth factor receptor (EGFR) inhibitor cetuximab is the only FDA-approved oncogene-targeting therapy for head and neck squamous cell carcinoma (HNSCC). Despite variable treatment response, no biomarkers exist to stratify patients for c
Externí odkaz:
https://doaj.org/article/0965f45254de4190931a8e6473149c38
Autor:
Anna Hecht, Julia A. Meyer, Astrid Behnert, Eric Wong, Farid Chehab, Adam Olshen, Aaron Hechmer, Catherine Aftandilian, Rukhmi Bhat, Sung Won Choi, Satheesh Chonat, Jason E. Farrar, Mark Fluchel, Haydar Frangoul, Jennifer H. Han, Edward A. Kolb, Dennis J. Kuo, Margaret L. MacMillan, Luke Maese, Kelly W. Maloney, Aru Narendran, Benjamin Oshrine, Kirk R. Schultz, Maria L. Sulis, David Van Mater, Sarah K. Tasian, Wolf-Karsten Hofmann, Mignon L. Loh, Elliot Stieglitz
Publikováno v:
Haematologica, Vol 107, Iss 1 (2020)
Mutations in the CBL gene were first identified in adults with various myeloid malignancies. Some patients with juvenile myelomonocytic leukemia (JMML) were also noted to harbor mutations in CBL, but were found to have generally less aggressive disea
Externí odkaz:
https://doaj.org/article/7bf4f7eb9c4b4077a05aebc0e4d3d3da
Autor:
Xiao-yong Li, Stewart MacArthur, Richard Bourgon, David Nix, Daniel A Pollard, Venky N Iyer, Aaron Hechmer, Lisa Simirenko, Mark Stapleton, Cris L Luengo Hendriks, Hou Cheng Chu, Nobuo Ogawa, William Inwood, Victor Sementchenko, Amy Beaton, Richard Weiszmann, Susan E Celniker, David W Knowles, Tom Gingeras, Terence P Speed, Michael B Eisen, Mark D Biggin
Publikováno v:
PLoS Biology, Vol 6, Iss 7 (2008)
Externí odkaz:
https://doaj.org/article/175b5384f9e344259f11b03237a5b905
Autor:
Xiao-yong Li, Stewart MacArthur, Richard Bourgon, David Nix, Daniel A Pollard, Venky N Iyer, Aaron Hechmer, Lisa Simirenko, Mark Stapleton, Cris L Luengo Hendriks, Hou Cheng Chu, Nobuo Ogawa, William Inwood, Victor Sementchenko, Amy Beaton, Richard Weiszmann, Susan E Celniker, David W Knowles, Tom Gingeras, Terence P Speed, Michael B Eisen, Mark D Biggin
Publikováno v:
PLoS Biology, Vol 6, Iss 2, p e27 (2008)
Identifying the genomic regions bound by sequence-specific regulatory factors is central both to deciphering the complex DNA cis-regulatory code that controls transcription in metazoans and to determining the range of genes that shape animal morphoge
Externí odkaz:
https://doaj.org/article/1c0cb54e3f884aad8d2824668852d428
Autor:
Valentina A. Zavala, Sandro Casavilca-Zambrano, Jeannie Navarro-Vásquez, Carlos A. Castañeda, Guillermo Valencia, Zaida Morante, Monica Calderón, Julio E. Abugattas, Henry Gómez, Hugo A. Fuentes, Ruddy Liendo-Picoaga, Jose M. Cotrina, Claudia Monge, Silvia P. Neciosup, Scott Huntsman, Donglei Hu, Sixto E. Sánchez, Michelle A. Williams, Angel Núñez-Marrero, Lenin Godoy, Aaron Hechmer, Adam B. Olshen, Julie Dutil, Elad Ziv, Jovanny Zabaleta, Bizu Gelaye, Jule Vásquez, Marco Gálvez-Nino, Daniel Enriquez-Vera, Tatiana Vidaurre, Laura Fejerman
Publikováno v:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 31, iss 8
Background: Breast cancer incidence in the United States is lower in Hispanic/Latina (H/L) compared with African American/Black or Non-Hispanic White women. An Indigenous American breast cancer–protective germline variant (rs140068132) has been rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0bd86dc0c3582edc36da5f555c29ec8
https://doi.org/10.1158/1055-9965.epi-22-0069
https://doi.org/10.1158/1055-9965.epi-22-0069
Autor:
Elliot Stieglitz, Adam B. Olshen, Julia Meyer, Jahan-Yar Parsa, Adam J. de Smith, Astrid Behnert, Mignon L. Loh, Aaron Hechmer
Publikováno v:
Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc1f60772b5d0732f4a13b87661232b
https://doi.org/10.1038/s41375-021-01331-0
https://doi.org/10.1038/s41375-021-01331-0
Autor:
Mark Fluchel, Margaret L. MacMillan, Sarah K. Tasian, Elliot Stieglitz, Rukhmi Bhat, Satheesh Chonat, Jason E. Farrar, Anna Hecht, Benjamin Oshrine, Dennis John Kuo, Eric Wong, Catherine Aftandilian, Aaron Hechmer, Maria Luisa Sulis, Kelly W. Maloney, Wolf-Karsten Hofmann, Julia Meyer, Haydar Frangoul, Adam B. Olshen, Aru Narendran, Astrid Behnert, Jennifer H. Han, Mignon L. Loh, David Van Mater, Farid F. Chehab, Sung Won Choi, Kirk R. Schultz, Edward A. Kolb, Luke Maese
Publikováno v:
Haematologica. 107:178-186
Mutations in the CBL gene were first identified in adults with various myeloid malignancies. Some patients with juvenile myelomonocytic leukemia (JMML) were also noted to harbor mutations in CBL, but were found to have generally less aggressive disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092f2aed67158eda9c89ea67f834bc56
https://doi.org/10.3324/haematol.2020.270595
https://doi.org/10.3324/haematol.2020.270595
Autor:
Jennifer Bolen, Neil E. Bhola, Stephen B. Keysar, Umamaheswar Duvvuri, Aaron Hechmer, Danielle L. Swaney, Antonio Jimeno, Mohammad Naser, Daniel Johnson, Kelechi Nwachuku, Tian Ran Zhu, Jennifer R. Grandis, Ritu Roy, Nevan J. Krogan, Rex H. Lee, Scott R. VandenBerg, Rachel A. O'Keefe, Adam B. Olshen, Mehdi Bouhaddou, Hua Li, Gordon B. Mills
Publikováno v:
JCI Insight
JCI insight, vol 6, iss 20
JCI insight, vol 6, iss 20
The epidermal growth factor receptor (EGFR) inhibitor cetuximab is the only FDA-approved oncogene-targeting therapy for head and neck squamous cell carcinoma (HNSCC). Despite variable treatment response, no biomarkers exist to stratify patients for c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e816d8577c3177e29fa0d32876fd5dca
https://pubmed.ncbi.nlm.nih.gov/34546978
https://pubmed.ncbi.nlm.nih.gov/34546978
Autor:
Todd P. Whitehead, Aaron Hechmer, Priyatama Pandey, Adam J. de Smith, Mi Zhou, Antoine M. Snijders, Catherine Metayer, Briana Fitch, Jian-Hua Mao, Scott C. Kogan, Abel Po-Hao Huang, Suzaynn F. Schick, Joseph L. Wiemels, Adam B. Olshen
Publikováno v:
Clinical science (London, England : 1979), vol 135, iss 8
Clinical Science (London, England : 1979)
Clinical Science (London, England : 1979)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children. Thirdhand smoke (THS) is the residual tobacco contamination that remains after the smoke clears. We investigated the effects of THS exposure in utero and during early life in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a77c67360f8a4c16414e39ef7f9334
https://escholarship.org/uc/item/4919n50n
https://escholarship.org/uc/item/4919n50n
