Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aaron Hartman"'
Autor:
R. Tucker Burks, Cory Brouwer, Justin T. Matulay, Connor Frasier, Aaron Hartman, David M. Foureau, James T. Kearns, Earle F. Burgess, Stephen B. Riggs, Peter E. Clark, Jason Zhu, Claud Grigg, Nury Steuerwald, J. Alexa Sanders, Kris E. Gaston
Publikováno v:
Transl Androl Urol
Background Intravesical bacillus Calmette-Guerin (BCG) therapy is standard treatment for high-risk non-muscle invasive bladder cancer (NMIBC) but overall efficacy is low, and no reliable predictive biomarkers currently exist to refine patient selecti
Autor:
Derek Raghavan, Jason Zhu, Aaron Hartman, Jiaxian He, Claud Grigg, Peter E. Clark, Chad A. Livasy, Earle F. Burgess
Publikováno v:
Human Pathology. 107:96-103
Summary Human epidermal growth factor receptor 2 (HER2) overexpression occurs in 5–10% of primary urothelial carcinomas (UCs) but has not reliably predicted benefit from HER2-targeted agents in the metastatic setting. HER2 testing of primary tumors
Autor:
Earle Burgess, Chad Livasy, Sally Trufan, Jason Zhu, Hazel O'connor, Aaron Hartman, Peter Clark, Claud Grigg, Derek Raghavan
Publikováno v:
Molecular and clinical oncology. 16(5)
Biomarkers are needed in muscle-invasive bladder cancer (MIBC). We previously reported that high tumor aurora kinase (AURK) A expression identifies patients with MIBC with poor prognosis. Aberrant p53 expression has also been associated with poor out
Autor:
Peter Clark, Blair Townsend, Tucker Burks, Jared Brown, James T. Kearns, Caroline Lu, Aaron Hartman, Caroline Miller, Samuel Ivan, Wei Sha
Publikováno v:
Journal of Urology. 206
INTRODUCTION AND OBJECTIVE:Prostate cancer referrals to high volume, academic cancer centers are common. Consulting urologic oncologists decide if outside prostate biopsy over-reads by internal pat...
Autor:
Sally Trufan, Renato Guerreri, Caroline Naso, Earle F. Burgess, Chad A. Livasy, Aaron Hartman, James T. Symanowski, Claud Grigg, Derek Raghavan, Peter E. Clark
Publikováno v:
Urologic oncology. 37(12)
Overexpression of aurora kinase A (AURKA) confers a poor prognosis in patients with urothelial carcinoma of the bladder. The prognostic value of high aurora kinase B (AURKB) expression in local bladder cancer is not well defined, and whether the prog
Autor:
Aaron Hartman, Earle F. Burgess, Chad A. Livasy, Caroline Naso, Derek Raghavan, Claud Grigg, Myra M. Robinson, James T. Symanowski, Peter E. Clark, Shannon E. Doherty, Stephen B. Riggs, Renato Guerrieri
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 37:299.e19-299.e25
Immune checkpoint inhibitors (ICI) targeting PD-(L)1 are effective in select patients with advanced urothelial carcinoma (UC). High PD-L1 expression enriches for response to ICIs; however, the predictive value of PD-L1 expression is limited, which ma
Autor:
James T. Symanowski, Aaron Hartman, Chad A. Livasy, Renato Guerrieri, Claud Grigg, Sally Jeanne Trufan, Peter E. Clark, Caroline Naso, Derek Raghavan, Earle F. Burgess
Publikováno v:
Journal of Clinical Oncology. 37:393-393
393 Background: Identification of robust biomarkers that predict likelihood of benefit from neoadjuvant chemotherapy (NAC) in patients with MIBC remains an unmet need. Previous studies have implicated tumor overexpression of aurora kinases A (AURKA)
Publikováno v:
Journal of Case Reports in Medicine. 1:1-4
Wegener's granulomatosis is an incurable vasculitis that can be life-threatening when end-organ damage occurs. Symptoms most commonly affect the nose, lungs, and kidneys. We present a case study of a 35-year-old male who presented with sequential bil
Autor:
Claud Grigg, Myra M. Robinson, Aaron Hartman, James T. Symanowski, Derek Raghavan, Renato Guerrieri, Shannon Doherty, Chad A. Livasy, Earle F. Burgess, Caroline Naso, Stephen Boyd Riggs, Kwabena Osei-Boateng, David L. Graham, Peter E. Clark
Publikováno v:
Journal of Clinical Oncology. 36:493-493
493 Background: Immune checkpoint inhibitors (ICI) targeting PD-1 or PD-L1 are effective in select patients with advanced UC. High PD-L1 expression enriches for response to ICIs; however, the predictive value of PD-L1 expression is limited, which may
Publikováno v:
American journal of orthopedics (Belle Mead, N.J.). 43(8)
It is unclear if healthy-appearing patellae in patients having total knee arthroplasty (TKA) can be selectively retained. In the study reported here, we hypothesized that grossly normal-appearing patellae in TKA candidates would show significant evid