Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Aaron Hansen"'
Autor:
Pavlina Spiliopoulou, Helena J. Janse van Rensburg, Lisa Avery, Vathany Kulasingam, Albiruni Razak, Philippe Bedard, Aaron Hansen, Andrzej Chruscinski, Ben Wang, Maria Kulikova, Rachel Chen, Vanessa Speers, Alisa Nguyen, Jasmine Lee, Bryan Coburn, Anna Spreafico, Lillian L. Siu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Despite more than 2 years having elapsed since the onset of SARS-CoV-2 pandemic, a level of hesitation around increased SARS-CoV-2 vaccine toxicity in cancer patients receiving immunotherapy (IO) remains. This hesitation stems from the idea
Externí odkaz:
https://doaj.org/article/b17872c511a140019f69a96a17a53131
Autor:
Chun Loo Gan, Shaan Dudani, J. Connor Wells, Frede Donskov, Sumanta K. Pal, Nazli Dizman, Nityam Rathi, Benoit Beuselinck, Flora Yan, Aly‐Khan A. Lalani, Aaron Hansen, Bernadett Szabados, Guillermo deVelasco, Ben Tran, Jae Lyun Lee, Ulka N. Vaishampayan, Georg A. Bjarnason, Mathushan Subasri, Toni K. Choueiri, Daniel Y. C. Heng
Publikováno v:
Cancer Medicine, Vol 10, Iss 4, Pp 1212-1221 (2021)
Abstract Background Cabozantinib is approved for metastatic renal cell carcinoma (mRCC) based on the METEOR and CABOSUN trials. However, real‐world effectiveness and dosing patterns of cabozantinib are not well characterized. Methods Patients with
Externí odkaz:
https://doaj.org/article/7d15b141c0ef4643936c243f3bc0a02a
Autor:
Dominick Bossé, Wanling Xie, Xun Lin, Ronit Simantov, Aly-Khan A. Lalani, Jeffrey Graham, J. Connor Wells, Frede Donskov, Brian Rini, Benoit Beuselinck, Ajjai Alva, Aaron Hansen, Lori Wood, Denis Soulières, Christian Kollmannsberger, Francois Patenaude, Daniel Y.C. Heng, Toni K. Choueiri, Rana R. McKay
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 293-306 (2020)
PURPOSETo investigate whether black race is an independent predictor of overall survival (OS) in metastatic renal cell carcinoma (mRCC).METHODSWe performed a retrospective 2-cohort (International Metastatic Renal Cell Carcinoma Database Consortium [I
Externí odkaz:
https://doaj.org/article/7f8755e52c91411ab1c49335f24de728
Autor:
Evan Hall, Carlo Bifulco, Aung Naing, Anthony Joshua, Georgina Long, Margaret Callahan, Brian Costello, Aaron Hansen, Brooke Shankles, Umut Ulge, Andrew Weickhardt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/38e40fada5b44f479af1ab007ac9ac25
Autor:
Sangjune Laurence Lee, Michael Cabanero, Martin Hyrcza, Marcus Butler, Fei-Fei Liu, Aaron Hansen, Shao Hui Huang, Ming-Sound Tsao, Yuyao Song, Lin Lu, Wei Xu, Douglas B. Chepeha, David P. Goldstein, Ilan Weinreb, Scott V. Bratman
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 17, Iss , Pp 32-39 (2019)
Oral tongue squamous cell carcinoma (OTSCC) displays variable levels of immune cells within the tumor microenvironment. The quantity and localization of tumor infiltrating lymphocytes (TILs), specific functional TIL subsets (e.g., CD8+), and biomarke
Externí odkaz:
https://doaj.org/article/04e5cd7c0269436ab354d25c7ee7f449
Autor:
John Hilton, Daniel Renouf, David W. Cescon, Aaron Hansen, Alibiruni Abdul Razak, Lee-Anne Stayner, Trisha A. Denny, Emily Roberts-Thomson, Dih-Yih Chen, Mark Bray, Philippe Bedard
Publikováno v:
Cancer Research. 83:P6-10
Background: TTK (also known as MPS1), a dual-specificity serine-threonine kinase, is critical for the spindle assembly checkpoint, chromosome alignment, and error correction in mitosis. Inhibition of TTK causes premature mitotic exit with unattached
Autor:
Pavlina Spiliopoulou, Helena J. Janse van Rensburg, Lisa Avery, Vathany Kulasingam, Albiruni Razak, Philippe Bedard, Aaron Hansen, Andrzej Chruscinski, Ben Wang, Maria Kulikova, Rachel Chen, Vanessa Speers, Alisa Nguyen, Jasmine Lee, Bryan Coburn, Anna Spreafico, Lillian L. Siu
Background Despite more than 2 years having elapsed since the onset of SARS-CoV-2 pandemic, a level of hesitation around increased SARS-CoV-2 vaccine toxicity in cancer patients receiving immunotherapy (IO) remains. Here, we explore serological respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb91ebab9457c43f0022777cbc31a8b
https://doi.org/10.21203/rs.3.rs-2214679/v1
https://doi.org/10.21203/rs.3.rs-2214679/v1
Autor:
Alberto Hernando-Calvo, Eoghan Malone, Daphne Day, Amy Prawira, Ilan Weinreb, Horace Wong, Angela Rodriguez, Sarah Jennings, Anneli Eliason, Lisa Wang, Anna Spreafico, Lillian L. Siu, Aaron Hansen
Background Salivary gland tumors (SGT) are rare with limited systemic treatments. We aimed to evaluate the activity of selinexor, an oral selective inhibitor of nuclear export, in patients with recurrent unresectable or metastatic SGT. Methods GEMS-0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87b9ae0362702b2b68f980da793a56ca
https://doi.org/10.21203/rs.3.rs-2114261/v1
https://doi.org/10.21203/rs.3.rs-2114261/v1
Autor:
Jeffrey Graham, John Connor Wells, Shaan Dudani, Chun L. Gan, Frede Donskov, Jae-lyun Lee, Christian K. Kollmannsberger, Luis Meza, Benoit Beuselinck, Aaron Hansen, Scott A. North, Georg A. Bjarnason, Nicolas Sayegh, Ravindran Kanesvaran, Lori A. Wood, Sebastien J. Hotte, Rana R. McKay, Toni K. Choueiri, Daniel Y.C. Heng
Publikováno v:
Graham, J, Wells, J C, Dudani, S, Gan, C L, Donskov, F, Lee, J L, Kollmannsberger, C K, Meza, L, Beuselinck, B, Hansen, A, North, S A, Bjarnason, G A, Sayegh, N, Kanesvaran, R, Wood, L A, Hotte, S J, McKay, R R, Choueiri, T K & Heng, D Y C 2022, ' Outcomes of patients with advanced non-clear cell renal cell carcinoma treated with first-line immune checkpoint inhibitor therapy ', European Journal of Cancer, vol. 171, pp. 124-132 . https://doi.org/10.1016/j.ejca.2022.05.002
Background: Immune checkpoint inhibitors (ICI) have demonstrated impressive activity in metastatic clear-cell renal cell carcinoma (ccRCC) and have become standard treatment options for patients with advanced disease. Data supporting the effectivenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf7f7a690f1adb77e00dfe925d16923
https://pure.au.dk/portal/da/publications/outcomes-of-patients-with-advanced-nonclear-cell-renal-cell-carcinoma-treated-with-firstline-immune-checkpoint-inhibitor-therapy(815bec8e-eed6-4416-8d49-526e10c3220b).html
https://pure.au.dk/portal/da/publications/outcomes-of-patients-with-advanced-nonclear-cell-renal-cell-carcinoma-treated-with-firstline-immune-checkpoint-inhibitor-therapy(815bec8e-eed6-4416-8d49-526e10c3220b).html