Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aaron H. Aziz"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract One major challenge observed for the expression of therapeutic bispecific antibodies (BisAbs) is high product aggregates. Aggregates increase the risk of immune responses in patients and therefore must be removed at the expense of purificati
Externí odkaz:
https://doaj.org/article/8cab4892c86c4270b94b3c96cdbbf671
Publikováno v:
ACS Appl Bio Mater
Osteocytes reside within a heavily mineralized matrix making them difficult to study in vivo and to extract for studies in vitro. IDG-SW3 cells are capable of producing mineralized collagen matrix and transitioning from osteoblasts to mature osteocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba75c114708047526ab0b3c58f92f43
https://doi.org/10.1021/acsabm.9b01227
https://doi.org/10.1021/acsabm.9b01227
Autor:
Stephanie J. Bryant, Aaron H. Aziz
Publikováno v:
Biotechnology and Bioengineering. 116:1523-1536
This study investigated osteogenesis of human mesenchymal stem cells encapsulated in matrix-metalloproteinase (MMP)-sensitive poly(ethylene glycol) (PEG) hydrogels in chemically defined medium (10 ng/ml bone morphogenic factor-2). Thiol-norbornene ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e037771e60e5da5ca2429706187e13
https://doi.org/10.1002/bit.26957
https://doi.org/10.1002/bit.26957
Autor:
Virginia L. Ferguson, Frank W. DelRio, Aaron H. Aziz, Stephanie J. Bryant, Aaron Sollner, Joseph A. Wahlquist
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 65:454-465
Multi-layer hydrogels are promising for tissue engineering due to the ability to control the local properties within each layer. However, the interface that forms between each layer has the potential to affect the performance of the hydrogel. The goa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0f376bb175a144932ba7543777152f
https://doi.org/10.1016/j.jmbbm.2016.09.007
https://doi.org/10.1016/j.jmbbm.2016.09.007
Publikováno v:
J Tissue Eng Regen Med
Bilayer hydrogels with a soft cartilage-like layer and a stiff bone-like layer embedded with human mesenchymal stem cells (hMSCs) are promising for osteochondral tissue engineering. The goals of this work were to evaluate the effects of dynamic compr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fc410409f8e77659e166ee70560032
https://europepmc.org/articles/PMC7408337/
https://europepmc.org/articles/PMC7408337/
Reinforcement of Mono- and Bi-layer Poly(Ethylene Glycol) Hydrogels with a Fibrous Collagen Scaffold
Autor:
Stephanie J. Bryant, A. Nelson, Virginia L. Ferguson, Brendan A.C. Harley, Aaron H. Aziz, Kirsten R. C. Kinneberg, Michael E. Stender, Laura C. Mozdzen
Publikováno v:
Annals of Biomedical Engineering. 43:2618-2629
Biomaterial-based tissue engineering strategies hold great promise for osteochondral tissue repair. Yet significant challenges remain in joining highly dissimilar materials to achieve a biomimetic, mechanically robust design for repairing interfaces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44b347fb750f833d8414660dd7e0c6b
https://doi.org/10.1007/s10439-015-1337-0
https://doi.org/10.1007/s10439-015-1337-0
Autor:
Stephanie J. Bryant, Corey P. Neu, Mark A. Randolph, Aaron H. Aziz, Frank W. DelRio, Chelsea M. Heveran, Joseph A. Wahlquist, Virginia L. Ferguson
Publikováno v:
Acta biomaterialia. 64
Osteoarthrosis is a debilitating disease affecting millions, yet engineering materials for cartilage regeneration has proven difficult because of the complex microstructure of this tissue. Articular cartilage, like many biological tissues, produces a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4814fbe8164b9a2ec61f80628e271a1c
https://pubmed.ncbi.nlm.nih.gov/29037894
https://pubmed.ncbi.nlm.nih.gov/29037894