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pro vyhledávání: '"Aaron Geno"'
Autor:
K. Aaron Geno, Mark A. Cervinski
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 28, Iss , Pp 63-66 (2023)
Background: Our laboratory historically performed immunosuppressant and definitive opioid testing in-house as laboratory developed (LDT) mass spectrometry-based tests. However, staffing constraints and supply chain challenges associated with the COVI
Externí odkaz:
https://doaj.org/article/fc640dc12d2248aa95a96020d7ee321d
Autor:
Grace R Williams, Gregory J Tsongalis, Lionel D Lewis, Rachael E Barney, Leanne J Cook, K Aaron Geno, Robert D Nerenz
Publikováno v:
The Journal of Applied Laboratory Medicine. 8:251-263
Background In the US adverse drug reactions (ADRs) are estimated to cause 100 000 fatalities and cost over $136 billion annually. A patient’s genes play a significant role in their response to a drug. Pharmacogenomics aims to optimize drug choice a
Publikováno v:
American Journal of Clinical Pathology.
Objectives This study examines whether patient outcomes were affected when the hemoglobin (Hb) transfusion threshold was lowered by 1 g/dL during COVID-19–related blood shortages. Methods Outcomes of lowered Hb thresholds (from Results Those in the
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209657 (2018)
Among 98 serotypes of Streptococcus pneumoniae, only a small subset regularly causes invasive pneumococcal diseases (IPD). We previously demonstrated that serotype 11A binds to ficolin-2 and has low invasiveness in children. Epidemiologic data sugges
Externí odkaz:
https://doaj.org/article/6cf17bf27a4b416fa803250582cbec9f
Publikováno v:
The American journal of emergency medicine. 61
Urinary tract infections (UTIs) seen in the emergency department are commonly treated as an outpatient with oral antibiotics. Given that antibiotics are available for over-the-counter purchase in Mexico, there is speculation that potential misuse and
Autor:
K Aaron Geno, Adina Badea, Kara L Lynch, Paul Jannetto, Jacqueline A Hubbard, Robert D Nerenz, Mark A Cervinski
Publikováno v:
The journal of applied laboratory medicine. 7(6)
Background Loperamide (Imodium®), a commonly used anti-diarrheal, is a mu opioid receptor agonist that, like all opioids, reduces gastrointestinal tract peristalsis. Loperamide is considered to have low abuse potential as it does not produce an anal
Autor:
K. Aaron Geno, Robert D. Nerenz
Publikováno v:
Critical reviews in clinical laboratory sciences. 59(7)
Thyroid hormones are primarily responsible for regulating the basal metabolic rate but also make important contributions to reproductive function and fetal development. Both hyper- and hypothyroidism in pregnancy have been associated with increased r
Autor:
Williams, Grace R, Tsongalis, Gregory J, Lewis, Lionel D, Barney, Rachael E, Cook, Leanne J, Aaron Geno, K, Nerenz, Robert D
Publikováno v:
Journal of Applied Laboratory Medicine; Mar2023, Vol. 8 Issue 2, p251-263, 13p
Akademický článek
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Publikováno v:
PeerJ, Vol 4, p e2705 (2016)
Ficolins can activate the lectin pathway of the complement system that provides innate immune protection against pathogens, marks host cellular debris for clearance, and promotes inflammation. Baseline inflammation increases with aging in a phenomeno
Externí odkaz:
https://doaj.org/article/7062ac420f5f484f8c58ec25f9bedc95