Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Aaron G, Maule"'
Autor:
Paul McVeigh, Erin McCammick, Emily Robb, Peter Brophy, Russell M Morphew, Nikki J Marks, Aaron G Maule
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 9, p e0011663 (2023)
Long non-coding (lnc)RNAs are a class of eukaryotic RNA that do not code for protein and are linked with transcriptional regulation, amongst a myriad of other functions. Using a custom in silico pipeline we have identified 6,436 putative lncRNA trans
Externí odkaz:
https://doaj.org/article/32c1dce9cf28411a925bd0b75c16be4c
Autor:
Natasha E. McGowan, Nikki J. Marks, Aaron G. Maule, Anne Schmidt-Küntzel, Laurie L. Marker, David M. Scantlebury
Publikováno v:
Movement Ecology, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Extinction is one of the greatest threats to the living world, endangering organisms globally, advancing conservation to the forefront of species research. To maximise the efficacy of conservation efforts, understanding the ecolog
Externí odkaz:
https://doaj.org/article/6749cb5e15484c8e9102f4e8a2a46fa3
Autor:
Francisco deCastro, Sina M. Adl, Stefano Allesina, Richard D. Bardgett, Thomas Bolger, Johnathan J. Dalzell, Mark Emmerson, Thomas Fleming, Diego Garlaschelli, Jacopo Grilli, Silja Emilia Hannula, Franciska deVries, Zoë Lindo, Aaron G. Maule, Maarja Öpik, Matthias C. Rillig, Stavros D. Veresoglou, Diana H. Wall, Tancredi Caruso
Publikováno v:
Ecology and Evolution, Vol 11, Iss 22, Pp 16070-16081 (2021)
Abstract Ecologists have long debated the properties that confer stability to complex, species‐rich ecological networks. Species‐level soil food webs are large and structured networks of central importance to ecosystem functioning. Here, we condu
Externí odkaz:
https://doaj.org/article/763e7ab56b7b44a7a1ff20f1ea2e74be
Autor:
Emily Robb, Erin M McCammick, Duncan Wells, Paul McVeigh, Erica Gardiner, Rebecca Armstrong, Paul McCusker, Angela Mousley, Nathan Clarke, Nikki J Marks, Aaron G Maule
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 11, p e0010854 (2022)
Fasciola spp. liver flukes have significant impacts in veterinary and human medicine. The absence of a vaccine and increasing anthelmintic resistance threaten sustainable control and underscore the need for novel flukicides. Functional genomic approa
Externí odkaz:
https://doaj.org/article/942dd2f73db1407ab6c0e8a48ec46440
Autor:
Bethany A. Crooks, Darrin Mckenzie, Luke C. Cadd, Ciaran J. McCoy, Paul McVeigh, Nikki J. Marks, Aaron G. Maule, Angela Mousley, Louise E. Atkinson
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The endocannabinoid signalling (ECS) system is a complex lipid signalling pathway that modulates diverse physiological processes in both vertebrate and invertebrate systems. In nematodes, knowledge of endocannabinoid (EC) biology is derived primarily
Externí odkaz:
https://doaj.org/article/9c5accc957de4090a4409b0b7fdf9cd0
Autor:
Armelle Buzy, Camille Allain, John Harrington, Dominique Lesuisse, Vincent Mikol, David F. Bruhn, Aaron G. Maule, Jean-Claude Guillemot
Publikováno v:
ACS Omega, Vol 6, Iss 15, Pp 10288-10305 (2021)
Externí odkaz:
https://doaj.org/article/0d3dfcf32203481a995ff60786dae934
Autor:
Paul McCusker, Wasim Hussain, Paul McVeigh, Erin McCammick, Nathan G. Clarke, Emily Robb, Fiona M. McKay, Peter M. Brophy, David J. Timson, Angela Mousley, Nikki J. Marks, Aaron G. Maule
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 46-55 (2020)
For over a decade RNA interference (RNAi) has been an important molecular tool for functional genomics studies in parasitic flatworms. Despite this, our understanding of RNAi dynamics in many flatworm parasites, such as the temperate liver fluke (Fas
Externí odkaz:
https://doaj.org/article/6adc572dca29437098a0058fa1081fd4
Autor:
Caoimhe M. Herron, Anna O’Connor, Emily Robb, Erin McCammick, Claire Hill, Nikki J. Marks, Mark W. Robinson, Aaron G. Maule, Paul McVeigh
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The liver fluke, Fasciola hepatica, is a global burden on the wellbeing and productivity of farmed ruminants, and a zoonotic threat to human health. Despite the clear need for accelerated discovery of new drug and vaccine treatments for this pathogen
Externí odkaz:
https://doaj.org/article/8fed6352ef33460a8b762cb901beaf7b
Autor:
Louise E. Atkinson, Ciaran J. McCoy, Bethany A. Crooks, Fiona M. McKay, Paul McVeigh, Darrin McKenzie, Allister Irvine, John Harrington, Bruce A. Rosa, Makedonka Mitreva, Nikki J. Marks, Aaron G. Maule, Angela Mousley
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Nematode parasites undermine human health and global food security. The frontline anthelmintic portfolio used to treat parasitic nematodes is threatened by the escalation of anthelmintic resistance, resulting in a demand for new drug targets for para
Externí odkaz:
https://doaj.org/article/8a21f17362a64b8da5c79e86ac91e8cd
Autor:
Carolina De Marco Verissimo, Heather L Jewhurst, Irina G Tikhonova, Rolf T Urbanus, Aaron G Maule, John P Dalton, Krystyna Cwiklinski
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008510 (2020)
Serine protease inhibitors (serpins) regulate proteolytic events within diverse biological processes, including digestion, coagulation, inflammation and immune responses. The presence of serpins in Fasciola hepatica excretory-secretory products indic
Externí odkaz:
https://doaj.org/article/889313ea57b844b6a4f283fbc357103b