Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aaron F. Phillips"'
Autor:
Alexandra M. Pinzaru, Robert A. Hom, Angela Beal, Aaron F. Phillips, Eric Ni, Timothy Cardozo, Nidhi Nair, Jaehyuk Choi, Deborah S. Wuttke, Agnel Sfeir, Eros Lazzerini Denchi
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2170-2184 (2016)
Genome sequencing studies have revealed a number of cancer-associated mutations in the telomere-binding factor POT1. Here, we show that when combined with p53 deficiency, depletion of murine POT1a in common lymphoid progenitor cells fosters genetic i
Externí odkaz:
https://doaj.org/article/41a03a414ad34762bf0a0a0270c0b8f8
Autor:
Aaron F. Phillips, Rumin Zhang, Akanksha Verma, Tamar Feinberg, Mia Jaffe, Marysol Chu Carty, Ryan Schulz, Sarah Bettigole, Celia Andreu, Scott Drutman, Michael Su, Derek Cogan, Christina H. Eng
Publikováno v:
Cancer Research. 83:517-517
Chromosome instability (CIN) is an attribute of cancer cells that has yet to be fully exploited therapeutically, despite its prevalence across many tumor types and lack of occurrence in normal cells. To identify genes uniquely essential to CINhigh ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4319c5a8ec94ce0d51a8db093c358eb8
https://doi.org/10.1158/1538-7445.am2023-517
https://doi.org/10.1158/1538-7445.am2023-517
Autor:
Koen van Besien, Aaron F. Phillips
Publikováno v:
Clinical Manual of Blood and Bone Marrow Transplantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eade383f3aad1d22af76bc76323fad2
https://doi.org/10.1002/9781119095491.ch20
https://doi.org/10.1002/9781119095491.ch20
Autor:
Dandan Shan, Linan Song, Ryan B. Hayman, Sean Sullivan, Brian A. Pink, Melissa Gardel, Lyndsey York, David C. Duffy, Kaitlin A. Minnehan, Mingwei Zhao, Aaron F. Phillips, David R. Walt
Publikováno v:
Analytical Chemistry. 85:1932-1939
We report a method for the sensitive measurement of genomic DNA based on the direct detection of single molecules of DNA in arrays of femtoliter wells. The method begins by generating short fragments of DNA from large, double-stranded molecules of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daff0b0b11f6da7c40b717d1b1b21c9d
https://doi.org/10.1021/ac303426b
https://doi.org/10.1021/ac303426b
Autor:
Hannah Crimmins, Agnel Sfeir, Sonia M. Dubois, Loelia Babin, Armêl R. Millet, Marco Tigano, Erika Brunet, Marion Piganeau, Marine Charpentier, Aaron F. Phillips
Publikováno v:
Molecular cell. 65(3)
Mutations in mtDNA lead to muscular and neurological diseases and are linked to aging. The most frequent aberrancy is the "common deletion" that involves a 4,977-bp region flanked by 13-bp repeats. To investigate the basis of this deletion, we develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19726d832bca946ef933f97f6f0ea1ff
https://pubmed.ncbi.nlm.nih.gov/28111015
https://pubmed.ncbi.nlm.nih.gov/28111015
Publikováno v:
Optics in the Life Sciences.
We have developed a platform using optical tweezers to create dynamic arrays of functionalized microbeads in microfluidic channels. The array is then exposed to analyte signaling molecules and washes, and interrogated using fluorescence microscopy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::299f90f44ac422038c0a315208c617a6
https://doi.org/10.1364/ota.2011.ottuc4
https://doi.org/10.1364/ota.2011.ottuc4
Autor:
Mael Manesse, Christopher N. LaFratta, Ryan B. Hayman, Aaron F. Phillips, David R. Walt, Manuel A. Palacios
Publikováno v:
Lab on a Chip. 13:2153
In this paper we present the development of an optical tweezers platform capable of creating on-demand dynamic microbead arrays for the multiplexed detection of biomolecules. We demonstrate the use of time-shared optical tweezers to dynamically assem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d29541400657075850c8373b8f8acce
https://doi.org/10.1039/c3lc00044c
https://doi.org/10.1039/c3lc00044c
Autor:
Angela Beal, Deborah S. Wuttke, Jaehyuk Choi, Eric Ni, Agnel Sfeir, Timothy Cardozo, Nidhi Nair, Aaron F. Phillips, Eros Lazzerini Denchi, Robert A. Hom, Alexandra M. Pinzaru
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2170-2184 (2016)
SummaryGenome sequencing studies have revealed a number of cancer-associated mutations in the telomere-binding factor POT1. Here, we show that when combined with p53 deficiency, depletion of murine POT1a in common lymphoid progenitor cells fosters ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e5add664860f415ae8092782fe84f4